Urban Metabolism of Paris and Its Region

The article presents the results of a research project aimed at (1) examining the feasibility of material flow analysis (MFA) on a regional and urban scale in France, (2) selecting the most appropriate method, (3) identifying the available data, and (4) calculating the material balance for a specific case. Using the Eurostat method, the study was conducted for the year 2003 and for three regional levels: Paris, Paris and its suburbs, and the entire region. Applying the method on a local scale required two local indicators to be defined in order to take into account the impact of exported wastes on MFA: LEPO, local and exported flows to nature, and DMC_corr, a modified domestic material consumption (DMC) that excludes exported wastes (and imported ones if necessary). As the region extracts, produces, and transforms less material than the country as a whole, its direct material input (DMI) is lower than the national DMI. In all the areas, LEPO exceeds 50% of DMI; in contrast, recycling is very low. The multiscale approach reveals that urban metabolism is strongly impacted by density and the distribution of activities: the dense city center (Paris) exports all of its wastes to the other parts of the region and concentrates food consumption, whereas the agricultural and urban sprawl area consumes high levels of construction materials and fuel. This supports the use of MFA on an urban and regional scale as a basis for material flow management and dematerialization strategies and clearly reveals the important interactions between urban and regional planning and development, and material flows.     

基于物质流分析方法的唐山市经济与环境关系的协整检验和分解

利用物质流分析方法(MFA)建立物质流账户,分析唐山市在经济 环境系统运行中物质投入量与产出量的阶段特征及物质投入和产出强度对经济发展的影响程度;使用计量经济学模型,分别对国内生产总值(GDP)、直接物质投入(DMI)和直接废弃物排放(DPO)进行单位根检验、Johansen协整检验、向量误差修正分析、脉冲响应和方差分解分析,探索了各指标之间的双向作用机制和长期关系.结果表明: 1992—2011年,唐山市DMI和DPO 均呈增长趋势,DMI的增幅高于DPO.DMI投入强度呈增长趋势,DPO产出强度呈波动下降趋势.GDP与DMI、DPO之间存在着长期稳定协整关系,指标间的作用关系经历了由波动到逐步平稳的过程.DMI与DPO在短期内会对经济发展起到较强的正向冲击作用,但是经济-环境系统会逐步消化这些影响,并对系统内外指标进行短期的动态调整,最终使系统表现出一种长期的均衡关系;经济发展受到经济规模效应的影响逐步增加.将各指标对GDP的贡献度予以分解,其中,DMI的贡献度上升,GDP的贡献度下降,DPO的贡献度变化不大.总体上,唐山市的经济发展遵循了资源型城市的传统生产轨迹,较大程度上依赖于物质投入,高能源消耗又加剧了环境污染.     

Rationale for and Interpretation of Economy-Wide Materials Flow Analysis and Derived Indicators

Economy-wide material flow analysis (MFA) and derived indicators have been developed to monitor and assess the metabolic performance of economies, that is, with respect to the internal economic flows and the exchange of materials with the environment and with other economies. Indicators such as direct material input (DMI) and direct material consumption (DMC) measure material use related to either production or consumption. Domestic hidden flows (HF) account for unused domestic extraction, and foreign HF represent the upstream primary resource requirements of the imports. DMI and domestic and foreign HF account for the total material requirement (TMR) of an economy. Subtracting the exports and their HF provides the total material consumption (TMC).
DMI and TMR are used to measure the (de-) coupling of resource use and economic growth, providing the basis for resource efficiency indicators. Accounting for TMR allows detection of shifts from domestic to foreign resource requirements. Net addition to stock (NAS) measures the physical growth of an economy. It indicates the distance from flow equilibrium of inputs and outputs that may be regarded as a necessary condition of a sustainable mature metabolism.
We discuss the extent to which MFA-based indicators can also be used to assess the environmental performance. For that purpose we consider different impacts of material flows, and different scales and perspectives of the analysis, and distinguish between turnover-based indicators of generic environmental pressure and impact-based indicators of specific environmental pressure. Indicators such as TMR and TMC are regarded as generic pressure indicators that may not be used to indicate specific environmental impacts. The TMR of industrial countries is discussed with respect to the question of whether volume and composition may be regarded as unsustainable.     

Uncertainties of Domestic Road Freight Statistics: Insights for Regional Material Flow Studies

Freight statistics are at the core of many studies in the field of industrial ecology because they depict the physical interdependencies of territories and allow links to be made worldwide between production and consumption. Recent studies have focused increasingly on subnational scales, often relying on domestic freight data. In this perspective, this article analyses the uncertainties of the French domestic road freight survey, road being by far the most common mode of transport in the country. Based on a statistical analysis of the survey, we propose a model to estimate the uncertainty of any given domestic road transport flow. We also assess uncertainty reduction when averaging the flows over several years, and obtain for instance a 30% reduction for a three‐year average. We then study the impact of the uncertainties on regional material flow studies such as the economy‐wide material flow analysis of the Bourgogne region. Overall the case studies advocate for a systematic assessment of freight uncertainties, as neither the disaggregation level nor the quantities traded are good enough predictors. This justifies the need for an easy‐to‐implement estimation model. Finally, basic comparison with the German and Swedish surveys tends to indicate that the main conclusions presented in this article are likely to be valid in other European countries.     

Transport proteins of Plasmodium falciparum: defining the limits of metabolism

In this review we give an account of transport processes occurring at the membrane interface that separates the asexual stage of Plasmodium falciparum from its host, the infected erythrocyte, and also describe proteins whose activities may be important at this location. We explain the potential clinical value of such studies in the light of the current spread of parasite resistance to conventional antimalarial strategies. We discuss the uptake of substrates critical to the survival of the intracellular malaria parasite, and also the parasite's homeostatic and disposal mechanisms. The use of the Xenopus laevis expression system in the characterisation of a hexose transporter ("PfHT1") and a Ca(2+) ATPase ("PfATP4") of the parasite plasma membrane are described in detail.     

物质流分析研究述评

物质流分析方法近年来在循环经济和可持续发展研究领域发展迅速。阐述了物质流分析的定义及其与自然生态系统物质流的区别,着重回顾了该研究方法的发展历程,阐明了物质流分析的主要观点、理论基础、研究思路及研究框架,详细阐译和对比分析了物质流分析的六大类指标及分析方法,并在物质流分析框架的基础上,建立循环经济及可持续发展的评价指标体系,并对物质流分析指标体系和方法学的研究意义及其在环境经济学中的地位进行了客观的评价,进而指出了物质流分析方法的不足之处。对物质流分析在不同层次的应用研究也进行了充分的阐述和分析。对物质流分析今后相关领域的进一步研究予以了讨论和展望。     

Resource Use in Small Island States

Iceland and Trinidad and Tobago are small open, high‐income island economies with very specific resource‐use patterns. This article presents a material flow analysis (MFA) for the two countries covering a time period of nearly five decades. Both countries have a narrow domestic resource base, their economy being largely based on the exploitation of one or two key resources for export production. In the case of Trinidad and Tobago, the physical economy is dominated by oil and natural gas extraction and petrochemical industries, whereas Iceland's economy for centuries has been based on fisheries. More recently, abundant hydropower and geothermal heat were the basis for the establishment of large export‐oriented metal processing industries, which fully depend on imported raw materials and make use of domestic renewable electricity. Both countries are highly dependent on these natural resources and vulnerable to overexploitation and price developments. We show how the export‐oriented industries lead to high and growing levels of per capita material and energy use and carbon dioxide emissions resulting from large amounts of processing wastes and energy consumption in production processes. The example of small open economies with an industrial production system focused on few, but abundant, key resources and of comparatively low complexity provides interesting insights of how resource endowment paired with availability or absence of infrastructure and specific institutional arrangements drives domestic resource‐use patterns. This also contributes to a better understanding and interpretation of MFA indicators, such as domestic material consumption.     

Intermodal network design: a three-mode bi-objective model applied to the case of Belgium

Freight transport planning is nowadays encouraged to align with environmental objectives. Among those, climate change is of particular interest for many countries. In its White Paper on Transport, the European Commission considers intermodal transport as a potential solution for reducing environmental impacts. In order to make good strategic transport decisions, realistic decision support models for freight transport networks must be developed, so that insights can be derived for the different stakeholders of the transportation chain. This research proposes a bi-objective mathematical formulation which takes into account economic and environmental objectives, on a road and intermodal network with three modes of transport (road, intermodal rail, and intermodal inland waterways), and in which economies of scale of intermodal transport can be considered. With this model better fitting reality, an application to the Belgian case study provides practical information on how flows, terminal types and locations vary depending on the chosen policy, on the integration or not of economies of scale, on costs or emissions modifications and on the number of terminals to locate. Results show that the chosen policy influences the terminal type and the intermodal market share. The study also highlights the interest of intermodal transport on short distances, and the risk of flow exchanges inside the intermodal market share, rather than between road and intermodal transport.     

Stand and shuffle: When does it make energetic sense?

Many reasons for the emergence of bipedalism have been proposed, including postural arguments which highlight that a sub-optimal form of bipedalism ("shuffling") might have been used by protohominids to cover short distances between resources that require bipedal standing. Bipedal shuffling may have been employed because it avoids the cost of raising the trunk from the quadrupedal orientation, which we assume is the habitual locomotor stance of protohominids. To date, these postural proposals have not been analytically assessed, a lack we rectify herein. Our model seeks to specify a threshold distance, below which bipedal shuffling uses less energy than quadrupedalism. Parameters for the model include the mechanical cost of transport, the ratio of bipedal to quadrupedal cost, and the cost associated with raising the trunk. We found that, using reasonable model parameters, open distances of approximately 9-16 m support the use of bipedal shuffling. Protohominids may have used shuffling as an energetically effective way to traverse between resource patches.     

Trade, Materials Flows, and Economic Development in the South: The Example of Chile

Materials flow analysis (MFA) is internationally recognized as a key tool to assess the biophysical metabolism of societies and to provide aggregated indicators for environmental pressures of human activities. Economy-wide MFAs have been compiled for a number of Organisation for Economic Cooperation and Development (OECD) countries, but so far very few studies exist for countries in the South. In this article, the first materials-flow-based indicators for Chile are presented. The article analyzes the restructuring of the Chilean economy toward an active integration in the world markets from the perspective of natural resource use in a time series from 1973 to 2000. Special emphasis is placed on the assessment of materials flows related to Chile's international trade relations. Results show that material inputs to the Chilean economy increased by a factor of 6, mainly as a result of the promotion of resource-intensive exports from the mining, fruit growing, forestry, and fishery sectors. At more than 40 tons, Chile's resource use per capita at present is one of the highest in the world. The article addresses the main shortcomings of the MFA approach, such as weightbased aggregation and the missing links between environmental pressures and impacts, and gives suggestions for methodological improvements and possible extensions of the MFA framework, with the intent of developing MFA into a more powerful tool for policy use.     

Material flow analysis and material use efficiency of Brazil's mortar and concrete supply chain

Cementitious materials, mostly concrete and mortar, account for about one‐third of all materials extraction worldwide. Material flow data in this industry are still unsatisfactory, especially related to unused extraction materials, quarry wastes, and water consumption, aspects which usually are not included in environmental analysis studies. The aim of this study is to conduct a material flow analysis (MFA) of the Brazilian concrete and mortar supply chain to quantify material use efficiency (ME) and dematerialization potential. The MFA includes extraction, production, and construction stages for the following indicators: i) unused extraction; ii) quarry waste; iii) water consumption; iv) material wastage; v) raw material consumption; vi) energy carriers; and vii) atmospheric emissions. The results demonstrated that the primary raw material footprint is about 456 million metric tons (Mt) corresponding to a metabolic rate of 2.2 metric tons/capita (t/capita). After including unused extraction, quarry wastes, water consumption, and secondary materials this value increases to 4.1 t/capita corresponding to a total material consumption of 840 Mt. Concrete and mortar can be produced using two routes—mixing on site or industrial mixing. We conclude that the industrial scenario allows for dematerialization by about 8% for concrete and 24% for mortar, by mass; and the average material use efficiency is low, at about 53% for concrete and 34% for mortar.     

Transport of 6-deoxyglucose in Saccharomyces cerevisiae.

The uptake of 6-deoxyglucose was measured in wild-type Saccharomyces cerevisiae, in a double mutant strain lacking activity for hexokinases A and B (hxkl hxk2), in a triple mutant strain lacking activity for both hexokinases and glucokinase (hxkl hxk2 glk), and in the triple mutant with high levels of activity of single kinases restored by introduction of the cloned genes. In the wild-type strain, uptake of the glucose analog showed two components, with Km values of ca. 20 mM ("high affinity") and 250 mM ("low affinity"), respectively. The double mutant also had high- and low-affinity components, but the triple mutant showed only low-affinity uptake. Reintroduction of the single kinases to the triple mutant restored high-affinity uptake. (Other experiments on 6-deoxyglucose uptake are also presented, including the apparent use of the galactose transport system when induced.) These results show that the recent implication of the kinases in transport of glucose (L.F. Bisson and D.G. Fraenkel, Proc. Natl. Acad. Sci. U.S.A. 80:1730-1734, 1983) applies equally to the nonmetabolized analog 6-deoxyglucose and suggests that the role of the kinases in transport is not merely a consequence of metabolism of the transported compound.     

Materials Flow Accounting in Sweden Material Use for National Consumption and for Export

This article presents Swedish economy‐wide material flow accounts for the period 1987‐1998. It also shows possibilities for enhancing the international comparability of aggregated data on material use, by distinguishing between materials used for consumption and export purposes. The direct material input (DMI) is used as an aggregate measure to estimate the amounts of natural resources (except water and air) that are taken from nature into the economy within a year, including imports to and production within the region in question. The division of materials used for consumption and export purposes avoids double counting trade flows when DMI is applied to a group of countries. The annual DMI in Sweden for 1997‐1998, including production and imports, amounts to 24 to 27 metric tons per capita (t/c). The fossil fuel input varies only slightly over the period, from 3.2 t/c in 1991 to 3.6 t/c in 1996, a level deemed unsustainable by the Swedish Environmental Protection Agency. The input of renewable raw materials varies between 8 and 9 t/c. Ores and minerals vary between 11 and 15 t/c. The DMI puts Sweden above estimates made for Germany, the United States, and Japan and in the same range as the Netherlands. The differences in these values can mainly be explained by the relative importance of exports as compared to the size of the economy and by the variation in system boundaries for the data on natural resources. The system boundaries and data sources for natural resources need to be further defined to make the measures fully comparable. Around 5 t/c is exported, whereas the rest, around 20 t/c, is national consumption. The aggregate direct material consumption (DMC), which is the DMI minus exports, communicates the magnitude of resource use. Comparisons of the input with solid waste statistics indicate that quantity of waste (excluding mining waste) in Sweden is equal to about 10% relative of the total resource use. Material collected for recycling by the waste management system is equal to about 5% of the amount of virgin resources brought into society each year.     

Material Flows and Economic Growth in Developing China

The concept of sustainable development concerns not only the natural environment but also human societies and economies. The method of economy‐wide materials flow accounting and analysis (EW‐MFA) is internationally recognized as a valuable tool for studying the physical dimensions of economies. EW‐MFA has been carried out in many industrialized countries, but very little work has been done for developing China; this article can be regarded as one of the first attempts to study China's economy in terms of materials flows. In this article we have compiled materials flow accounts for China during the time series 1990 to 2002 and derived indicators associated with international comparison. Results show that the annual material consumption of China's economy continuously increased except for a slump around 1998, whereas the material efficiency exhibited a three‐phase trend reflecting different macropolicies of the Eighth, Ninth, and Tenth Five‐Year Plans implemented by the central government. Based on this experience with EW‐MFA for China, suggestions for methodology development and further research are given for improving EW‐MFA as a more effective tool for environmental management.     

Transport of thyroxine across the blood-brain barrier is directed primarily from brain to blood in the mouse

The role of the blood-brain barrier (BBB) in the transport of thyroxine was examined in mice. Radioiodinated ("hot") thyroxine (hT4) administered icv had a half-time disappearance from the brain of 30 min. This increased to 60 min (p less than 0.001) when administered with 211 pmole/mouse of unlabeled ("cold") thyroxine (cT4). The Km for this inhibition of hT4 transport out of the brain by cT4 was 9.66 pmole/brain. Unlabeled 3,3',5 triiodothyronine (cT3) was unable to inhibit transport of hT4 out of the brain, although both cT3 (p less than 0.05) and cT4 (p less than 0.05) did inhibit transport of radioiodinated 3,3',5 triiodothyronine (hT3) to a small degree. Entry of hT4 into the brain after peripheral administration was negligible and was not affected by either cT4 nor cT3. By contrast, the entry of hT3 into the brain after peripheral administration was inhibited by cT3 (p less than 0.001) and was increased by cT4 (p less than 0.01). The levels of the unlabeled thyroid hormones administered centrally in these studies did not affect bulk flow, as assessed by labeled red blood cells (99mTc-RBC), or the carrier-mediated transport of iodide out of the brain. Likewise, the vascular space of the brain and body, as assessed by 99mTc-RBC, was unchanged by the levels of peripherally administered unlabeled thyroid hormones. Therefore, the results of these studies are not due to generalized effects of thyroid hormones on BBB transport. The results indicate that in the mouse the major carrier-mediated system for thyroxine in the BBB transports thyroxine out of the brain, while the major system for triiodothyronine transports hormone into the brain.     

Life Cycle Inventories of Transport Services: Background Data for Freight Transport (10 pp)

Background, Goal and Scope The ecoinvent database is a reference work for life cycle inventory data covering the areas of energy, building materials, metals, chemicals, paper and cardboard, forestry, agriculture, detergents, transport services and waste treatment. Generic inventories are available for freight and passenger transport including air, rail, road, and water transport. The goal of freight transport modelling is to provide background data for transport services, which occur between nearly any two process steps of a product system. This paper presents and discusses the model structure, basic assumptions and results for selected freight transport services.Main Features Transport services are divided into several datasets referred to as transport components. In addition to vehicle operation (comprising vehicle travel and pre-combustion), infrastructure processes such as vehicle maintenance, manufacturing and disposal, as well as transport infrastructure construction, operation and disposal, are also modelled. In order to link the various transport components to the functional unit of one tonne kilometre (tkm), so-called demand factors are determined. In the case of transport infrastructure that is not exclusively used by freight transport, allocation is essential. The respective allocation parameters employed for line infrastructure construction/disposal and operation datasets (including land use) are yearly Gross-tonne kilometre performance (Gtkm) and kilometric vehicle/train performance. Results are presented for selected environmental exchanges related to gaseous emissions (climate change gases, nitrogen oxides, and hydrocarbons), heavy metal (zinc and cadmium) emissions to soil and air, as well as BOD (Biological Oxygen Demand), and land use. Particle emissions are further distinguished into fine (PM2.5) and coarse (diameter between 2.5 and 10 µm) particles. The results presented comprise both an intra- and inter-modal comparison.Results and Discussions A comparison of Swiss and European rail transport reveals considerably lower emissions from Swiss rail transport due to the almost exclusive use of hydropower as traction energy. For gaseous emissions, freight transport by water or rail exhibits considerably better performance than road transport (65-92% less gaseous emissions). As far as zinc and cadmium emissions to soil are concerned, water and rail transport produce less than 1% of the emissions resulting from road transport for either pollutant. For zinc and cadmium emissions to air, road transport has the highest emissions; however, the emissions due to water and rail transport range from 2 to 18% of the emission levels arising from road transport. Particle emissions show a more diverse pattern. Whilst fine particle emissions due to water and rail transport are considerably lower than road transport, rail transport with respect to coarse particles performs worse than road transport. Dominance analysis reveals the importance of infrastructure processes. For instance, the NMHC-emissions of infrastructure processes account for 40%, 30% and 50% of emissions for road, rail and barge transport, respectively. For the demand factor of infrastructure operation, a sensitivity analysis of the employed allocation factor was performed, revealing no sensitivity for gaseous emissions and particles. On the other hand, considerable changes in both emission levels and in the ranking of transport modes is observed for land occupation. Finally, we varied selected operation parameters for road transport, resulting in considerable reductions of CO2 and NOX emissions of up to 60%. In one extreme case (load factor: 100%), NOx emissions for vehicle operation of a lorry are lower than for inland water transport. Only as a result of the considerably higher NOx emissions occurring in infrastructure processes does road transport score worse than water transport, with the ranking remaining the same as for the generic data presented in ecoinvent 2000.Conclusions and Perspectives The provided datasets allow for a preliminary screening of the importance of transport processes within a product life cycle. In the cases for which transport processes are identified as sensitive for the overall outcome of certain product life cycle or for transport specific comparisons, the modular structure and transparent documentation of demand factors allows for an easy and transparent integration of more case-specific data for selected transport components.     

Materials Metabolism Analysis of China's Highway Traffic System (HTS) for Promoting Circular Economy

With the rapid growth of highway mileage and vehicles, the Chinese highway traffic system (HTS) has become one of the great resource consumers. This article attempts to evaluate the material metabolism of China's HTS during 2001–2005 using the approach of material flow analysis (MFA) and to explore possible measures to promote circular economy throughout HTS. We measured a set of indicators to illustrate the whole material metabolism of China's HTS. The results indicated that the direct material input (DMI) of China's HTS increased from 1181.26 million tonnes (Mt) in 2001 to 1,874.57 Mt in 2005, and about 80% of DMI was accumulated in the system as infrastructure and vehicles. The domestic processed output (DPO) increased by 59.0% from 2001 to 2005. Carbon dioxide and solid waste accounted for 80.5% and 10.4% of DPO, respectively. The increase of resource consumption and pollutant emissions kept pace with the growth of transportation turnover. All these suggest that China's HTS still followed an extensive linear developing pattern with large resource consumption and heavy pollution emissions during the study period, which brought great challenges to the resources and the environment. Therefore, it's high time for China to implement a circular economy throughout the HTS by instituting resource and energy savings, by reducing emissions in the field of infrastructure construction and maintenance, by reducing vehicles’ energy and materials consumption, and by recycling waste materials.     

Decomposition Analysis of Finnish Material Flows: 1960–1996

To the extent that environmental impacts are the consequence of the magnitude of total material input into production in an economy, they can be lessened by reducing the use of materials—by concentrating on what has been called qualitative growth. This article presents a summary of Finnish resource use over the period 1960–1996 as a means of evaluating the trends in material use and providing a basis for assessments of sustainability. It adapts the technique of decomposition analysis developed in the field of energy studies to distinguish the effects of changes in aggregate economic activity ("activity effect"), composition of industrial activity ("structural effect") and materials intensity of use ("intensity effect") on a sectoral basis.p
According to the analysis presented here, materials consumption in Finland has grown substantially between 1960 and 1996 in the electricity, gas and water supply, pulp and paper production, civil engineering, and mining and quarrying sectors. In the same period, the ratio of GDP/mass of material mobilized has improved by 175 percent. Economic growth has caused the largest increases in materials use in the building of infrastructures; for example roads, waterways, means of supplying electricity, gas, and water, and in the production of paper and paper products. The least growth took place in the transport, basic metals production, and mining and quarrying sectors.     

产业生态系统资源代谢分析方法

产业生态系统是由企业群、资源及环境组成的社会-经济-环境复合生态系统。资源代谢是其功能运行的重要保障。资源代谢在时间和空间尺度上的耗竭及阻滞是造成严重生态环境问题的主要原因。根据生态学原理,运用物质流分析手段解析了产业生态系统的物质流、能流及资金流结构,构建了产业生态系统资源代谢分析模型,提出了资源输入-使用-输出-循环共生四方面的资源代谢分析指标体系和基于模糊综合分析的资源代谢问题树分析方法。在此基础上提出了基于循环共生网络结构模型的生态管理模式。以期为产业资源的生态管理提供方法支撑。     

Transport kinetics of uncoupling proteins. Analysis of UCP1 reconstituted in planar lipid bilayers

According to alternative hypotheses, mitochondrial uncoupling protein 1 (UCP1) is either a proton channel ("buffering model") or a fatty acid anion carrier ("fatty acid cycling"). Transport across the proton channel along a chain of hydrogen bonds (Grotthus mechanism) may include fatty acid carboxyl groups or occur in the absence of fatty acids. In this work, we demonstrate that planar bilayers reconstituted with UCP1 exhibit an increase in membrane conductivity exclusively in the presence of fatty acids. Hence, we can exclude the hypothesis considering a preexisting H+ channel in UCP1, which does not require fatty acid for function. The augmented conductivity is nearly completely blocked by ATP. Direct application of transmembrane voltage and precise current measurements allowed determination of ATP-sensitive conductances at 0 and 150 mV as 11.5 and 54.3 pS, respectively, by reconstituting nearly 3 x 10(5) copies of UCP1. The proton conductivity measurements carried out in presence of a pH gradient (0.4 units) allowed estimation of proton turnover numbers per UCP1 molecule. The observed transport rate of 14 s-1 is compatible both with carrier and channel nature of UCP1.