Neural mechanisms underlying amblyopia.

The nature of the neural basis of amblyopia is a matter of some debate. Recent neurophysiological data show correlates of amblyopia in the spatial properties of neurons in primary visual cortex. These neuronal deficits are probably the initial manifestation of the visual loss, but there are almost certainly additional deficits at higher levels of the visual pathways.     

The foveal reflex in amblyopia

The relative brightness of the foveal reflex between amblyopic eyes and their fellows was examined. Differences in reflex appearances were found in some patients but not in others. Equal appearance of the foveal reflexes does not eliminate the possibility of amblyopia, nor is there a difference in appearance related to the degree of amblyopia.