Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells

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A Chemical Probe that Labels Human Pluripotent Stem Cells

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Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells

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Nanog Is Dispensable for the Generation of Induced Pluripotent Stem Cells

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A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

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Histone Variants Enriched in Oocytes Enhance Reprogramming to Induced Pluripotent Stem Cells

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Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells

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Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

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Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution

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Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells

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Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition

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NPTX1 Regulates Neural Lineage Specification from Human Pluripotent Stem Cells

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SIP1 Mediates Cell-Fate Decisions between Neuroectoderm and Mesendoderm in Human Pluripotent Stem Cells

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Highlights? Smad-interacting protein 1 (SIP1) regulates hESC differentiation ? SIP1 upregulation promotes neuroectodermal differentiation ? SIP1 inhibits mesendodermal and endodermal differentiation ? SMAD2/3 and NANOG/OCT4/SOX2 cooperatively regulate SIP1 expression     

High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping

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Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination

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Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells

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The let-7/LIN-41 Pathway Regulates Reprogramming to Human Induced Pluripotent Stem Cells by Controlling Expression of Prodifferentiation Genes

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Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells

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Tcf15 Primes Pluripotent Cells for Differentiation

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Highlights? Tcf15 marks a subpopulation of pluripotent cells primed for somatic lineages ? Tcf15 expression is regulated by FGF signaling ? Tcf15 activity is repressed by Id proteins ? Tcf15 represses Nanog and drives differentiation once released from Id inhibition