Inhibition of the succinic oxidase system by some structural analogs of succinic and malonic acids

The desoxyribonucleic acid and the ribonucleic acid have been prepared from pneumococcus type VI organism by a new method which has excluded deproteinization and treatment with enzymes. The yields are not high.     

On the role of K+ on succinic dehydrogenase activity

The effect of potassium ions on succinic dehydrogenase activity of mitochondria was studied. The results showed that in these organelles K⁺ induces inhibition of the respiratory control; moreover, in submitochondrial particles potassium inhibits the rate of oxidation of succinate. The results showed also that K⁺ does not changes theK _m for succinate but diminishes theV _max. In addition, the data provide evidence that mitochondria oxidizing glutamatemalate in a sucrose medium show a higher activity of succinate dehydrogenase than mitrochondria incubated in KCl.