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1.
Purpose
The purpose of this work is to identify and select safeguard subjects and state indicators that are suitable for sustainability assessment in product and production development, using an interpretation of the Brundtland definition of sustainable development. The purpose is also to investigate how indicators selected in this way differ from other selections in the literature.Methods
We use a top-down approach, which starts with reviewing the Brundtland definition of sustainability and identifying the corresponding human basic needs to be satisfied. For each basic need, we identify relevant satisfiers, and for each satisfier, a number of safeguard subjects. The safeguard subjects represent critical resources for making satisfiers available. For each safeguard subject, a number of state indicators (=endpoint category indicators) are selected that are relevant for describing impacts from product life cycles on the safeguard subject.Results and discussion
Ecosystem services, access to water, and abiotic resources are identified as environmental safeguard subjects. Technology for transports, environment, textiles, housing, food, information, and energy, together with income, are identified as economical safeguard subjects. Human health, land availability, peace, social security, continuity, knowledge, jobs/occupation, and culture are identified as social safeguard subjects. In comparison with the other selections of safeguard subjects in literature, our safeguard subjects are structured differently and delimited in scope, but there are also many similarities. The best agreement is on environmental issues, but we classify human health as a social issue. For social issues, we identify fewer safeguard subjects and state indicators than recommendations from UNEP/SETAC. For economic issues, we diverse from current LCC and approach UNECE measures of sustainability.Conclusions
Identification and selection of safeguard subjects and state indicators benefit from a clear definition of sustainability, needs to be satisfied, and satisfiers. The interpretation of the sustainability concept has a large influence on which safeguard subjects that are included and which indicators that are needed to describe their state. Capacity building is an important sustainability indicator, which should be developed further for use in life cycle sustainability assessment. The top-down approach offers a good arena for a further research and discussions on how to structure and focus LCSA. Our results shall be seen as one example of which safeguard subject that may be identified with the top-down approach presented here.2.
João Fontes Peter Tarne Marzia Traverso Paula Bernstein 《The International Journal of Life Cycle Assessment》2018,23(3):547-555
Purpose
Whereas the business evolution of environmental sustainability metrics has advanced significantly over the past decade, social sustainability at product level is still relatively immature. Research continues to support the front runners on organisational sustainability, while workable solutions at product level have not yet been addressed sufficiently. Triggered by this imbalance, a group of experts from large companies decided to join forces, initiating the Roundtable for Product Social Metrics.Methods
Starting in early 2013, this group of companies aimed to (i) consolidate principles for product social sustainability assessment and harmonise approaches, (ii) align with other global initiatives and share with other companies and (iii) develop solutions for cross-cutting implementation issues. In order to be able to produce a comprehensive method for social impact assessment that provides enough flexibility for individual requirements, the Roundtable developed a method based on the approaches of the participant companies and external references such as the UNEP/SETAC Guidelines for Social Life-Cycle Assessment of Products and corporate level standards. Guiding principles were defined for the development of the method.Results and discussion
The results of the first two phases of the Roundtable for Product Social Metrics are documented in a handbook, which proposes a practical method for organisations to assess the social impacts of a product or a service along its life cycle. The handbook outlines an aligned method for social impact assessment at a product level offering two approaches: quantitative and scale based. The method was developed to allow reasoned assessment of overall performance by including social topics and performance indicators that reflect positive and negative impacts of the product on three stakeholder groups: workers, consumers and local communities. Nineteen social topics are proposed, together with their individual performance indicators, including detailed definitions. Application examples and recommendations for the communication of results are also included in the handbook.Conclusions
The method can be applied in numerous scenarios, from understanding improvement opportunities and steering product development in different stages, to providing support for decision making and external communications. However, the method still has further potential for improvement, inter alia that the proposed indicators are not fully applicable to small farmers, SMEs and the self-employed, as well as that the indicators are mainly at inventory level. Furthermore, the proposed method is strongly dependent on the availability of data.3.
Ann-Kristin Nyman Ann Lindberg Charlotte Hallén Sandgren 《Acta veterinaria Scandinavica》2011,53(Z1):S8
Background
Pre-recorded register data from dairy herds are available in almost all Nordic countries. These databases can be used for research purposes, and one of the research areas is animal welfare. The aim of this study was to investigate if pre-recorded register data could be used to identify herds with good welfare, and to investigate if a combination of register data sets could be used to be able to more correctly distinguish between herds with good welfare and herds with welfare deficiencies.Methods
As a first step, nine animal-based measurements on calves, young stock and cows in 55 randomly selected herds were performed on-farm as the basis for a classification of welfare at the herd level. The definition for being a case herd with “good welfare” was no score lying among the 10% worst in any of the nine welfare measurements. Twenty-eight of the 55 herds were cases according to this definition. As a second step, 65 potential welfare indicators, based on register data in a national dairy database, were identified by expert opinion. In the final step, the extent to which the suggested welfare indicators predicted farms’ as having good welfare according to the stated definition was assessed. Moreover, the effect of combining in sequence a previously developed model that identified herds with poor welfare with the present model identifying herds with good welfare was investigated.Results
The final set of welfare indicators used to identify herds with good animal welfare included two fertility measures, cow mortality, stillbirth rate, mastitis incidence and incidence of feed-related diseases (including gastrointestinal disturbances but excluding paralyses and cramps). This set had a test sensitivity of correctly classifying herds with no score lying among the 10% worst of the nine welfare measurements of 96 %. However, the specificity of the test was only 56% indicating difficulties for the test to correctly classifying herds with one or more scores lying among the 10% worst. Combining the previously developed model with the present model, improved the welfare classification.Conclusions
This study shows that pre-collected register data may be used to give approval to dairy farms with “good welfare” and that combining different sets of register data can improve the classification of herd welfare.4.
Massimo Pizzol Marco Scotti 《The International Journal of Life Cycle Assessment》2017,22(7):1146-1158
Purpose
The consequential inventory modeling approach for life cycle assessment implies that an increase in the demand for a specific product is met by the marginal suppliers within the market. The identification of marginal suppliers is however complicated by difficulties in defining appropriate geographical market delimitations. In this study, an advanced system thinking approach is proposed to address this challenge in the identification of marginal supplying countries of wood products.Methods
Groups of countries which represent geographical markets are identified from trade data by using a network analysis-based clustering technique. Within these markets, marginal supplying countries are selected based on positive historical increments. The analysis covers 12 different products and all countries in the world using trade data for the period 1998–2013.Results and discussion
Global indices allow differentiating how product-specific trade networks are separated into communities and how interconnected these networks are. Large differences between products and minor differences between trade years are observed. Communities identified for each product tend to overlap with existing geographical regions and seem thus realistic. By combining this information with product-specific production increment rankings, marginal supplying countries of wood products were identified.Conclusions
The identified geographical market delimitation is a key for proper consequential life cycle assessment (LCA) inventory modeling in areas such as timber-based construction and biomass-based energy production. The method can in principle be applied to any product for which trade network data are available and ideally should be accompanied by a detailed analysis of technological constrains within the identified supplying country.5.
N. Cesbron A.-L. Royer Y. Guitton A. Sydor B. Le Bizec G. Dervilly-Pinel 《Metabolomics : Official journal of the Metabolomic Society》2017,13(8):99
Introduction
Collecting feces is easy. It offers direct outcome to endogenous and microbial metabolites.Objectives
In a context of lack of consensus about fecal sample preparation, especially in animal species, we developed a robust protocol allowing untargeted LC-HRMS fingerprinting.Methods
The conditions of extraction (quantity, preparation, solvents, dilutions) were investigated in bovine feces.Results
A rapid and simple protocol involving feces extraction with methanol (1/3, M/V) followed by centrifugation and a step filtration (10 kDa) was developed.Conclusion
The workflow generated repeatable and informative fingerprints for robust metabolome characterization.6.
Seppo Junnila 《The International Journal of Life Cycle Assessment》2008,13(5):432-439
Background, aim, and scope
Today, the effective integration of life cycle thinking into existing business routines is argued to be the most critical step for more sustainable business models. The study tests the suitability of an input–output life cycle assessment (IO-LCA) approach in screening life cycle impacts of energy-using products in companies. It estimates the life cycle impacts of three products and assesses the suitability of such approach in a company environment.Materials and methods
The multiple case studies evaluate the suitability of an IO-LCA method in a company environment. A comprehensive life cycle cost and impact study of three product systems (building ventilation system, information and communication technology (ICT) network product, and welding machine) is conducted and the life cycle phases with highest economical and environmental contribution are determined. Scenario analysis is performed in order to assess the sensitivity of the results to major changes in the studied systems. Finally, the usability of the IO-LCA approach for environmental evaluations in companies is assessed by collecting data on workload and interviewing the participating workers and managers.Results
The results showed that the use phase with operating energy was environmentally important in all evaluated energy-using products. However, only in one case (ICT network product) the use was the single most significant life cycle phase. In two other cases, the sourcing was equally important. The results also indicated that the IO-LCA approach is much easier to adapt by current management of companies because it automatically links life cycle costs to environmental indicators and, by order of magnitude, reduces the workload in companies.Discussion
It appears that the IO-LCA approach can be used to screen environmentally significant life cycle phases of energy-using products in companies by utilizing readily available accounting or other documented data. The IO-LCA approach produced comparable results with the ones published in traditional process-based LCA literature. In addition to the main results, some practical benefits of using the IO-LCA could also be suggested: the approach was very fast to use and would thus allow an easier adoption of environmental evaluations in companies as well as wider environmental testing of products in early conceptual design phase.Conclusions
The results indicated that the IO-LCA approach could clearly offer added value to the environmental management of companies. The IO-LCA was found to provide a very fast access to the key life cycle characteristics of products. Similarly, it offered practical means to integrate life cycle thinking into existing business routines and to activate the decision makers in companies by giving them easily comprehendible results.Recommendations and perspectives
The results would suggest that similar environmental IO tables, besides the US ones used here, would have value and should be collected for other major geographical and economical regions. The tables would enable a much larger share of companies to manage their environmental issues. It also seems that, because the user profile is so dominant in the case of energy-using products, more studies, both theoretical (How to valuate the future behavior in environmental studies?) and empirical (What really creates value for users?), should focus on the behavior of users.7.
Breno Barros Telles do Carmo Manuele Margni Pierre Baptiste 《The International Journal of Life Cycle Assessment》2017,22(12):2007-2017
Purpose
In social life cycle assessment (SLCA), to measure the social performance, it is necessary to consider the subcategory indicators related to each stakeholder dimension, such as workers, local community, society, consumers and value chain participants. Current methods in SLCA scientific literature consider a standard arbitrary linear score set to translate qualitative performances into a quantitative assessment for all subcategory indicators, i.e., it translate a A, B, C, D scoring into a 4, 3, 2, 1 ordinal scale. This assumption does not cover the complexity of the subcategory indicators in the social life cycle assessment phase. The aim of this paper is to set out a customized scoring and weighting approach for impact assessment in SLCA beyond the assumption of arbitrary linearity and equal weighting.Methods
This method overcomes the linearity assumption and develops specific value functions for each subcategory indicator and an approach to establish the weighting factors between the indicators for each social dimension (workers, local community, and society). The value function and weighting factors are based on the considered opinions of SLCA experts in Québec.Results and discussion
The results show that value functions with different shapes used to score the performance of the product within each subcategory indicator influence SLCA results and have the potential to reverse the conclusions. The customized score is more realistic than the linear score because it can better capture the complexity of the subcategory indicators based on SLCA expert judgment.Conclusions
Our approach addresses a methodological weakness of the impact assessment phase of SLCA through a more representative performance of the potential social impacts based on the judgment of the SLCA expert rather than a simplified assumption of linearity and equal weighting among indicators. This approach may be applied to all types of product systems.Recommendations
The value functions and weighting factors cannot be generalized for all cases and the proposed approach must be adapted for each study. We stopped at the aggregation of the subcategory indicators based on expert judgment at the stakeholder level. If a complete aggregation in a single score is required, we recommend developing a framework that accounts for the value judgment of the decision-maker rather than the SLCA expert.8.
Caroline Ivanne Le Roy Luke John Mappley Roberto Marcello La Ragione Martin John Woodward Sandrine Paule Claus 《Metabolomics : Official journal of the Metabolomic Society》2016,12(10):157
Introduction
Poultry is one of the most consumed meat in the world and its related industry is always looking for ways to improve animal welfare and productivity. It is therefore essential to understand the metabolic response of the chicken to new feed formulas, various supplements, infections and treatments.Objectives
As a basis for future research investigating the impact of diet and infections on chicken’s metabolism, we established a high-resolution proton nuclear magnetic resonance (NMR)-based metabolic atlas of the healthy chicken (Gallus gallus).Methods
Metabolic extractions were performed prior to 1H-NMR and 2D NMR spectra acquisition on twelve biological matrices: liver, kidney, spleen, plasma, egg yolk and white, colon, caecum, faecal water, ileum, pectoral muscle and brain of 6 chickens. Metabolic profiles were then exhaustively characterized.Results
Nearly 80 metabolites were identified. A cross-comparison of these matrices was performed to determine metabolic variations between and within each section and highlighted that only eight core metabolites were systematically found in every matrice.Conclusion
This work constitutes a database for future NMR-based metabolomic investigations in relation to avian production and health.9.
Renato de Souza Pinto Lemgruber Kaspar Valgepea Mark P. Hodson Ryan Tappel Sean D. Simpson Michael Köpke Lars K. Nielsen Esteban Marcellin 《Metabolomics : Official journal of the Metabolomic Society》2018,14(3):35
Introduction
Quantification of tetrahydrofolates (THFs), important metabolites in the Wood–Ljungdahl pathway (WLP) of acetogens, is challenging given their sensitivity to oxygen.Objective
To develop a simple anaerobic protocol to enable reliable THFs quantification from bioreactors.Methods
Anaerobic cultures were mixed with anaerobic acetonitrile for extraction. Targeted LC–MS/MS was used for quantification.Results
Tetrahydrofolates can only be quantified if sampled anaerobically. THF levels showed a strong correlation to acetyl-CoA, the end product of the WLP.Conclusion
Our method is useful for relative quantification of THFs across different growth conditions. Absolute quantification of THFs requires the use of labelled standards.10.
Amanda Marie Lubold 《International breastfeeding journal》2017,12(1):34
Background
The objective of this study is to examine the effects of macro-level factors – welfare state policies and public health initiatives – on breastfeeding initiation among eighteen high-income countries.Methods
This study utilizes fuzzy-set Qualitative Comparative Analysis methods to examine the combinations of conditions leading to both high and low national breastfeeding initiation rates among eighteen high-income countries.Results
The most common pathway leading to high breastfeeding initiation is the combination of conditions including a high percentage of women in parliament, a low national cesarean section rate, and either low family spending, high rates of maternity leave, or high rates of women working part-time. The most common pathway leading to low breastfeeding initiation includes the necessary condition of low national adherence to the Baby-Friendly Hospital Initiative.Conclusion
This research suggests that there is a connection between broad level welfare state polices, public health initiatives, and breastfeeding initiation. Compliance with the WHO/UNICEF initiatives depends on welfare regime policies and overall support for women in both productive and reproductive labor.11.
Seung Jin Kim Sami Kara Michael Hauschild 《The International Journal of Life Cycle Assessment》2017,22(8):1257-1265
Purpose
The static functional unit definition in the current LCA framework has limitations in addressing the changing product functionality and associated environmental impact of constantly evolving product technologies. As a result, it overlooks the changes in consumer behaviour of increased consumption of products in provided services as well as in growing volumes. This article aims to present a new framework in defining a dynamic functional unit of product technologies that caters for changes in consumer behaviour and growing market.Methods
A new approach to defining the functional unit is proposed that caters for changes in consumer behaviour and the use of technology from a technical performance perspective. A dynamic approach to definition of the functional unit is proposed that is based on Kano’s model of product function and satisfaction.Results and discussion
The new approach is demonstrated on a case study in which the analysis of historical data for two TV product technologies—CRT and LCD—is used to show how the total environmental impact is increasing due to the increased functionality which triggers an increase in the volume of the market. Despite the efforts of improving product life cycle design, the society is still faced with increasing environmental impact from the product type overall.Conclusions
This article presents the challenges of using a static, single functional unit definition in an industrial culture with constant evolution of products that influences usage behaviour and demonstrates the vicious circle of improving product efficiency that leads to further consumption and environmental impact. To address this problem, a new framework of dynamic functional unit definition is put forward for performing comparative LCA to manage the development of product life cycle design that helps keep the total environmental impact of the company’s product portfolio within absolute boundaries.12.
John S. Woods Mattia Damiani Peter Fantke Andrew D. Henderson John M. Johnston Jane Bare Serenella Sala Danielle Maia de Souza Stephan Pfister Leo Posthuma Ralph K. Rosenbaum Francesca Verones 《The International Journal of Life Cycle Assessment》2018,23(10):1995-2006
Purpose
Life cycle impact assessment (LCIA) results are used to assess potential environmental impacts of different products and services. As part of the UNEP-SETAC life cycle initiative flagship project that aims to harmonize indicators of potential environmental impacts, we provide a consensus viewpoint and recommendations for future developments in LCIA related to the ecosystem quality area of protection (AoP). Through our recommendations, we aim to encourage LCIA developments that improve the usefulness and global acceptability of LCIA results.Methods
We analyze current ecosystem quality metrics and provide recommendations to the LCIA research community for achieving further developments towards comparable and more ecologically relevant metrics addressing ecosystem quality.Results and discussion
We recommend that LCIA development for ecosystem quality should tend towards species-richness-related metrics, with efforts made towards improved inclusion of ecosystem complexity. Impact indicators—which result from a range of modeling approaches that differ, for example, according to spatial and temporal scale, taxonomic coverage, and whether the indicator produces a relative or absolute measure of loss—should be framed to facilitate their final expression in a single, aggregated metric. This would also improve comparability with other LCIA damage-level indicators. Furthermore, to allow for a broader inclusion of ecosystem quality perspectives, the development of an additional indicator related to ecosystem function is recommended. Having two complementary metrics would give a broader coverage of ecosystem attributes while remaining simple enough to enable an intuitive interpretation of the results.Conclusions
We call for the LCIA research community to make progress towards enabling harmonization of damage-level indicators within the ecosystem quality AoP and, further, to improve the ecological relevance of impact indicators.13.
Luigia Petti Monica Serreli Silvia Di Cesare 《The International Journal of Life Cycle Assessment》2018,23(3):422-431
Purpose
The main purpose of this review is to investigate the methodology of social life cycle assessment (SLCA) through its application to case studies. In addition, the following research aims to define the trends related to the SLCA by researchers and consultants. This study will help to map the current situation and to highlight the hot spots and weaknesses of the application of the SLCA theory.Methods
The SLCA could be considered as a useful methodology to provide decision support in order to compare products and/or improve the social effects of the life cycle of a product. Furthermore, the results of the case studies analyzed may influence decision makers significantly. For this reason, a systematic literature review of case studies was carried out in which SLCA was applied in order to analyze closely the application of the stages of this methodology. In this study, the major phases of the technical framework for a SLCA were analyzed. Specific attention was paid to detect the positive impacts that emerged in the case studies, which were also studied by administering a questionnaire to the authors of the analyzed case studies and to a number of experts in the field of SLCA.Results and discussion
The 35 case studies examined in this paper, even though they do not deviate from the 40 identified by the previous processing, are still significantly different in terms of outcome produced. It is important to clarify that the authors who developed the case studies considered the steps defined in the SETAC/SETAC guidelines, borrowed from the ISO 14044 standard.Conclusions
The data resulting from this analysis could help both practitioners and researchers to understand what the issues are, on which it is still necessary to investigate and work, in order to solidify the SLCA methodology and define its role in the context of life cycle sustainability assessment (LCSA).14.
Background
Tail biting is a common welfare problem in pig production and in addition to being a sign of underlying welfare problems, tail biting reduces welfare in itself. The aim of this study was to evaluate the effects of tail biting on different pre and post mortem indicators of stress in slaughter pigs and on carcass and meat characteristics. A total of 12 tail bitten (TB) and 13 control (C) pigs from a farm with a long-term tail biting problem were selected for salivary cortisol analyses before and after transport to the slaughterhouse. After stunning, samples were taken for the analysis of serum cortisol, blood lactate, intestinal heat shock protein 70 (HSP70), and meat quality characteristics. In addition, body temperature immediately after and muscle temperature 35 min after stunning were measured, as well as lean meat percentage and carcass weight.Results
TB pigs showed a lower cortisol response to the transport-induced stress than C pigs and also had a lower serum cortisol concentration after stunning. HSP70 content in the small intestine was higher in the TB pigs than in C pigs. TB pigs had a considerably lower carcass weight therefore produced a lower total amount of lean meat per carcass than C pigs.Conclusions
This study suggests that prolonged or repeated stress in the form of tail biting causes a blunted stress response, possibly a sign of hypocortisolism. In addition, it underlines the importance of reducing tail biting, both from an animal welfare and an economic point-of-view.15.
Tiago G. Morais Ricardo F. M. Teixeira Tiago Domingos 《The International Journal of Life Cycle Assessment》2016,21(6):875-884
Purpose
One of the main trends in life cycle assessment (LCA) today is towards increased regionalization in inventories and impact assessment methods. LCA studies require the collection of activity data but also of increasingly region-specific background data to accurately depict supply chain processes and enable the application of an increasing number of geographically explicit impact assessment models. This is particularly important for agri-food products. In this review, we assess progress in Portugal towards this goal and provide recommendations for future developments.Methods
We perform a comprehensive review of available LCA studies conducted for Portuguese agri-food products, in order to evaluate the current state of Portuguese agri-food LCA. Among other issues, we assess availability of data, methods used, level of regionalization, impact assessment model relevance and coherence for inter-product comparability. We also provide conclusions and recommendations based on recent developments in the field.Results and discussion
We found 22 LCA studies, covering 22 different products. The analysis of these studies reveals limitations in inter-study comparability. The main challenges have to do with a lack of country-specific foreground data sources applied consistently in the studies found, with discrepancies in impact assessment categories, and with the use of simple functional units that may misrepresent the product analyzed.Conclusions
We conclude that Portuguese agri-food LCA studies do not have a systematic and country-scale approach in order to guarantee regional accuracy and comparability. We propose a research strategy to engage the Portuguese agri-food LCA community in devising a consistent framework before practical application studies are conducted.16.
Christian R. Vogl Brigitte Vogl-Lukasser Michael Walkenhorst 《Journal of ethnobiology and ethnomedicine》2016,12(1):40
Background
The sustainable management of animal health and welfare is of increasing importance to consumers and a key topic in the organic farming movement. Few systematic studies have been undertaken investigating farmers’ local knowledge related to this issue. Ethnoveterinary medicine (EVM) is a discipline focusing on local knowledge and folk methods in veterinary medicine, however most ethnoveterinarian studies primarily address the treatment of animal diseases. Very few studies have explored prophylactic methods.Methods
An ethnoveterinary research project in Eastern Tyrol (Austria) was conducted in 2004 and 2005 to gather information about local knowledge of animal husbandry from 144 informants, with the emphasis on plants that maintain livestock health and welfare.Results
Informants mentioned a total of 87 plants and 22 plant-based generic terms in the context of maintaining and improving livestock health and welfare. The most important preventive measures for maintaining and improving animal health and welfare were practices related to “fodder” and “feeding”. In this category the plants mentioned could be grouped according to three different perceptions about their effect on animals: “Good or bad fodder”, “Functional fodder” and “Fodder medicine”. In addition to fodder, environmental management, the human-animal relationship, household remedies and cultural/religious activities were also mentioned. When asked about practices in the past that maintained animal health and well-being, interviewees mentioned, for example, the importance of the diversity of sources that used to be available to obtain feed and fodder.Conclusions
The informants’ approach that feeding is central to livestock welfare is in line with the standard scientific literature on animal health, including in organic farming. Various scientific studies into common fodder evaluate the nutritive and dietary value, efficiency and safety of fodder. Future studies also have to consider the evaluation of traditional, local fodder resources. In fact, the value of ‘food as medicine’ for humans in the context of local knowledge has been widely assessed, but the potential health benefits of fodder and nutraceuticals in local and traditional ethnoveterinary methods require further attention.17.
Marzia Traverso Lynn Bell Peter Saling João Fontes 《The International Journal of Life Cycle Assessment》2018,23(3):597-606
Purpose
The main goal of this paper is to present the feasibility of the quantitative method presented in the Product Social Impact Assessment (PSIA) handbook throughout a case study. The case study was developed to assess the social impacts of a tire throughout its entire life cycle. We carried out this case study in the context of the Roundtable for the Product Social Metrics project in which 13 companies develop two methodologies, a qualitative and a quantitative one, for assessing the social impact of product life cycle.Methods
The quantitative methodology implemented for assessing the social impact of a Run On Flat tire mounted in a BMW 3 series consists of 26 indicators split in three groups. Each group represents a stakeholder group. Primary data of the quantitative indicators were collected along the product life cycle of the Run On Flat by involving the companies, which owned the main steps of the product life cycle. Throughout this case study, an ideal/worst-case scenario was defined for the distance-to-target approach to compare the social performances of more products when they are available.Results and discussion
The implementation of the PSIA quantitative method to a Run On Flat illustrated the necessity to have a referencing step in order to interpret the results. This is particularly important when the results are used to support decision-making process in which no experts are involved. It frequently happens in a big company where the management level has to take often decisions on different topics. Reference values were defined using ideal or worst-case-target scenarios (Fontes et al. 2014). For those topics where it was possible, an ideal/ethical scenario was defined, e.g., 0 h of child labor per product. In other cases, we defined a worst-case scenario, e.g., 0 training hours per product. It was then possible to interpret the results using a distance-to-target approach. A matrix was developed in the case study for identifying in which step of the product life cycle data is not available; that means we need more transparency in the supply chain.Conclusions
Each value of the matrix can be compared to the ideal/worst scenario to compare the step to each other and to identify along the product life cycle which step and the relative supplier that needs further measures to improve the product performance. Furthermore, a quantitative value for each indicator related to the product life cycle is calculated and compared with the ideal/worst scenario. The case study on Run On Flat represents the first implementation of the quantitative method of PSIA.18.
Alexandre Souza Marcos Djun Barbosa Watanabe Otavio Cavalett Cassia Maria Lie Ugaya Antonio Bonomi 《The International Journal of Life Cycle Assessment》2018,23(3):617-628
Purpose
The main goal of this study is to suggest quantitative social metrics to evaluate different sugarcane biorefinery systems in Brazil by exploring a novel hybrid approach integrating social life cycle assessment and input-output analysis.Methods
Social life cycle assessment is the main methodology for evaluating social aspects based on a life-cycle approach. Using this framework, a hybrid model integrating social life cycle assessment and input-output analysis was introduced to evaluate different social effects of biorefinery scenarios considering workers as the stakeholder category. Job creation, occupational accidents, wage profile, education profile, and gender profile were selected as the main inventory indicators. A case study of three scenarios considering variations in agricultural and industrial technologies (including sugarcane straw recovery and second-generation ethanol production, for instance) was carried out for evaluating present first-generation (1G-basic, 1G-optimized) and future first- and second-generation ethanol production (1G2G).Results and discussion
The 1G-basic scenario leads to higher job creation levels over the supply chain mainly because of the influence of agricultural stage whose workers are mostly employed in sugarcane manual operations. On the other hand, 1G-optimized and 1G2G present supply chains are more reliant on the manufacturing, trade, and services sectors whose workers are associated with a lower level of occupational accidents, higher average wages, higher education level, and more participation of women in the work force.Conclusions
The use of a novel hybrid approach integrating social life cycle assessment (SLCA) and input-output analysis (IOA) was useful to quantitatively distinguish the social effects over different present and future sugarcane biorefinery supply chains. As a consequence, this approach is very useful to support decision-making processes aiming to improve the sustainability of sugarcane biorefineries taking social aspects into account.19.
Zichen?Yang Jian?Sun Xiaofeng?Yang Zhiyuan?Zhang Bangwei?Lou Jian?Xiong Hermann?J?Schluesener Zhiren?Zhang
Background
Experimental autoimmune neuritis (EAN) is a well-known animal model of human demyelinating polyneuropathies and is characterized by inflammation and demyelination in the peripheral nervous system. Fascin is an evolutionarily highly conserved cytoskeletal protein of 55 kDa containing two actin binding domains that cross-link filamentous actin to hexagonal bundles.Methods
Here we have studied by immunohistochemistry the spatiotemporal accumulation of Fascin?+?cells in sciatic nerves of EAN rats.Results
A robust accumulation of Fascin?+?cell was observed in the peripheral nervous system of EAN which was correlated with the severity of neurological signs in EAN.Conclusion
Our results suggest a pathological role of Fascin in EAN.Virtual slides
The virtual slides for this article can be found here: http://www.diagnosticphatology.diagnomx.eu/vs/673459345111481120.
Wenhao Chen Nicholas M. Holden 《The International Journal of Life Cycle Assessment》2017,22(9):1459-1472