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To determine the prevalence of hepatitis A in a Canadian Inuit population, serum from 85% of the 850 inhabitants of Baker Lake, Northwest Territories, was tested by radioimmunoassay for antibody to the hepatitis A virus (anti-HAV). The overall prevalence of anti-HAV in the community was 71%. Exposure to the virus occurred early in life, such that by the age of 6 years 53% of the children had anti-HAV in their serum. The rate approached 100% by the age of 50 years. These findings document the ubiquitous nature of the hepatitis A virus in this northern Inuit settlement and suggest that immunoprophylaxis be considered for individuals taking short-term employment in such places.  相似文献   

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Paraoxonase phenotype distribution in Canadian Indian and Inuit populations   总被引:1,自引:0,他引:1  
Test objects were the sera of 57 North American Indian and 67 Inuit subjects. The paraoxon-hydrolyzing activity, a, was determined, as well as the paraoxonase-phenotyping ratio, c/b, a ratio designating enzyme activation by Na+ in the presence of Ca2+. The values of c/b were clearly bimodally distributed. Location of the modes and of the antimodal gap were in perfect agreement with the results previously obtained on Caucasian sera. This allowed us to retain the criterion which had been already established in the study of Caucasians, i.e., c/b less than 1.5 = "low-activity" phenotype, and c/b greater than 1.5 = "high-activity" phenotype. The proportions of individuals in each mode differed, however. In Caucasians, the frequency of the "low-activity" phenotype had been estimated as 51.2%. In Indians and Inuits, it was 7.0% and 6.0%, respectively. Independent of phenotype, Indian and Inuit sera displayed lower paraoxon-hydrolyzing activity than did Caucasian sera.  相似文献   

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Spondylolysis of the lower back, particularly that involving the isthmus between the superior and inferior articular processes (pars inter-articularis), is generally attributed to stress fracturing caused by movement of the affected vertebra relative to the vertebra below. The finding of isthmic spondylolysis in the first vertebra of a fused sacrum is thus unusual and requires explanation. Although unrepresented in the clinical literature, sacral spondylolysis has been reported for archaeological specimens and appears to be especially prevalent in North American Inuit. A study of 373 Inuit sacra from Alaska and Canada produced 16 examples of spondylolysis (eight from each area). All but one of the affected individuals were male, and nearly all were young adults, many between 18 and 20 years of age. All cases of sacral spondylolysis observed in this study were judged to have resulted from stress fracturing that occurred while S1 was still unfused, and most appear to have been in the process of healing, following fusion of S1 with S2, when death occurred. The high frequency observed in these people is attributed to unusual stresses becoming concentrated in the lower back of adolescent males due to such activities as weight lifting, wrestling, kayak paddling, and harpooning, combined with, and perhaps even contributing to, delayed maturation (S1-S2 fusion) of the sacrum. © 1996 Wiley-Liss, Inc.  相似文献   

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Data from the medical records of 113 patients living in Manitoba who had contracted respiratory poliomyelitis between 1952 and 1959 were compared with information obtained from interviews with these patients in 1980. The study was designed to determine whether the patients'' respiratory function, mobility, ability to perform daily tasks, and employment, residential and marital status had changed between 1 year after the onset of polio and 1980. The patients'' dependence on mechanical aids and other people was also studied. More than half (56%) of the patients perceived their respiratory impairment to be the same as it was 1 year after the onset of polio, 27% perceived the impairment to be increased, and 17% perceived it to be decreased. There was an association between level of respiratory function, mobility and ability to perform daily tasks. The 69 patients who lived at home had better respiratory function, mobility and ability to perform daily tasks than the 24 patients who were assisted by a home care program and the 20 who lived in hospital. The latter group had the lowest levels of respiratory and functional ability.  相似文献   

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The understanding of intelligence and cognitive functioning of culturally diverse peoples has long been an interest of social scientists. It has also long been recognized that environmental factors and cultural values affect both perceptual abilities and the display of cognitive functioning. While some scholars have proposed the existence of multiple forms of intelligence, others have argued that the assessment of intelligence requires the application of local definitions of intelligence and intelligent behavior. In the present paper I explore the concept of intelligence in the small Copper Inuit community of Holman. Data collected between 1978 and 1995 are used to examine the manner in which community members define, assess, and develop intelligence. Modernity has created new conditions in which intelligence is nurtured and assessed.
Particular attention is paid to informant efforts to encourage the author to behave intelligently. [Inuit, theories of intelligence, participant-observation]  相似文献   

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The provisioning and administration of social housing has been a continuous problem in the Canadian North since the 1960s, when the Canadian government began taking an active role in the welfare of Inuit. Some of these problems are quite basic and include high costs for construction and maintenance of units. An examination of the development and evolution of Canadian housing policy in the North demonstrates that changes to the administration of social housing programs and, since the mid-1980s, development of formal privatization schemes have steadily shifted housing costs onto local residents. These shifting costs, however, are borne unequally, with Inuit born and raised in the context of permanent communities (the Settlement Generation) facing the greatest burdens.  相似文献   

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K. M. Douglas  G. Fisher  D. Reeleder 《CMAJ》1982,126(8):923-926
In recent years modifications and refinements in treating varicose veins by injecting a sclerosant have given this method an important place in the practitioner''s armamentarium. Specific indications and precise technique are essential. Compression-sclerotherapy has been used since 1975 in the vein clinic of Belleville General Hospital, Belleville, Ont. Some patients have also required limited ligation of veins that were deeper or more proximal, or both. A follow-up study of patients 2 or more years after treatment revealed no major complications and a high rate of patient acceptance and satisfaction. The costs of treatment were about one tenth those of conventional inpatient surgery.  相似文献   

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B. D. Postl  N. Nelson  J. Carson 《CMAJ》1982,126(7):811-813
A prospective study was undertaken to determine if Inuit and Caucasian neonates have different patterns of physiologic jaundice. Daily blood samples obtained by heel pricks of Inuit and Caucasian neonates born at the Churchill (Man.) Health Centre were assayed for the total serum bilirubin concentration. The mean peak bilirubin level in the Inuit group was significantly higher than that in the Caucasian group (8.76 v. 6.04 mg/dl [150 v. 103 mumol/l]) and occurred later (on day 3 rather than day 2). Of the Caucasian neonates, those who were breast-fed in hospital had a significantly higher (P less than 0.05) mean peak bilirubin level than those who were not, and among all the neonates who were not breast-fed in hospital the Inuit had a significantly higher mean peak bilirubin level than the Caucasians (7.98 v. 3.64 mg/dl [136 v. 62 mumol/l]). These findings indicate that factors other than breastfeeding, some of which may be genetic, are responsible for the higher and later peak in the serum bilirubin concentration in Inuit neonates.  相似文献   

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Electric stimulation of the diaphragm via the phrenic nerve to induce ventilation has recently been used for the long-term management of chronic ventilatory insufficiency. Since 1973 three patients with inadequate alveolar ventilation have been treated with diaphragm pacing at the Toronto Western Hospital. Two, who had quadriplegia due to lesions of the spinal cord in the upper cervical region and a severe restrictive ventilatory defect, were treated with continuous diaphragm pacing. The third patient required assisted nocturnal ventilation because of primary alveolar hypoventilation. All three patients tolerated the diaphragm pacing well, and pulmonary function tests showed satisfactory gas exchange with the patients breathing room air. This form of therapy seems to be a practical clinical method of managing chronic ventilatory failure in patients with lesions of the upper cervical cord or primary alveolar hypoventilation.  相似文献   

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Forty-three patients, 38 women and 5 men, with self-inflicted skin lesions were studied. Thirty-three were followed up for up to 22 years. In most cases dermatitis artefacta was only one incident in a long history of psychogenic illness. Of the 43 patients, 13 (30%), 12 women and one man, continued to produce lesions or were disabled with other psychiatric disorders more than 12 years after the onset of symptoms. Prognosis was difficult but recovery seemed to occur when the patient''s life circumstances changed rather than as a result of treatment.  相似文献   

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Beluga whale hunting is one of the most social subsistence hunting activities to take place in the Canadian Arctic. Through the harvest, distribution and consumption of beluga whales, Inuit identity and social relationships are affirmed. The whale-hunting complex is influenced by beliefs that beluga whales are sentient beings who inhabit a shared social space with humans. Yet, across the region beluga whales are perceived by wildlife managers as scarce resources and as such require protection through the imposition of management plans. There is currently no management of whales on the west coast of Hudson Bay, in Nunavut. In 2002, Inuit there were requested to sell part of their whale harvest to Inuit in Nunavik, northern Quebec, where hunting quotas exist. The outcome of this event was concern in Nunavut for the future of the whale hunt, and a deepening sense of powerlessness in Nunavik due to the management of the whale harvest.
Martina TyrrellEmail:
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Surveys in 1969/1970, 1979/1980, and 1989/ 1990 assessed physical fitness among adult Inuit living in Igloolik, Northwest Territories, Canada, during a period of rapid acculturation to a sedentary lifestyle. MANOVA for age, cohort, and age-cohort effects indicated significant trends to greater skinfold readings [male (M) and female (F)] and body mass (F only), a lower handgrip and knee extension force (M and F), and lower step test predictions of aerobic power (M and F) in the more recent cohorts, with no change of forced vital capacity, 1-s forced expiratory volume, or hemoglobin level. By 1989/1990, continuing hunters tended to have thicker skinfolds than other villagers, and showed no advantage of aerobic power. The average fitness of the sample when tested in 1989/1990 was comparable with that of sedentary populations in Southern Canada, but a minority of villagers who now practiced regular sport had conserved the high levels of fitness that were observed in 1969/1970. We conclude that the fitness of this community appears to have deteriorated markedly as it has become more sedentary, and we thus recommend that health authorities develop methods of promoting an active lifestyle that are culturally appropriate to the populations of circumpolar settlements.  相似文献   

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