Behavioral Indexes of Poor Welfare in Laboratory Rats

A study compared the behavior of rats kept under standard conditions with the behavior of those from enriched, semi-enriched, and single-housed conditions to determine whether standard conditions have detrimental effects on nonhuman animal welfare. The subjects were 35 female Hooded Norway rats. Using an emergence box, open field, and Hebb-Williams maze, the study measured the subjects' behaviors. Housing conditions significantly affected the behavior of the rats as measured by all 3 procedures. The results of the rats from standard conditions were intermediate between those of the single-housed and the more enriched groups. Thus, enrichng the standard environment would ameliorate behavioral deficits in rats kept under standard conditions.     

Detection of Hepatitis E Virus Antibodies in Dogs in the United Kingdom

Hepatitis E virus (HEV) genotypes 3 and 4 are zoonotic pathogens, with pigs predominantly implicated in disease transmission. The rapid rise in human cases in developed countries over the past decade indicates a change in epidemiology of HEV, and it has been suggested that additional animal species may be involved in transmission of infection. Multiple studies have identified contact with dogs as a risk factor for HEV infection in industrialised nations, and a low seroprevalence to HEV has previously been reported in dogs in low-income countries. In this study we aimed to evaluate the possibility that dogs are susceptible to HEV, and determine the frequency with which this occurs. Serum samples from UK dogs with and without hepatitis were screened for HEV-specific antibodies, and canine liver and stool samples were analysed by qPCR for the presence of HEV RNA. We describe evidence to show HEV infection occurs at low levels in dogs in the UK, but the strain of origin is undetermined. The low seroprevalence level of HEV in dogs implies the risk of zoonotic disease transmission is likely to be limited, but further investigations will be required to determine if HEV-infected dogs can transmit HEV to man.     

Ability of the Public to Recognize Dogs Considered to Be Dangerous under the Dangerous Dogs Act in the United Kingdom

Canine aggression came into the public eye in the United Kingdom in the late 1980s prompting enactment of the UK Dangerous Dogs Act , which prohibits four breeds or “types” of dogs. The act faced strong opposition surrounding correct identification of prohibited dogs. A questionnaire was distributed to the public via an online platform, especially targetting those who have worked with dogs. The questionnaire assessed respondents’ abilities to identify the four banned types of dogs from other breeds and their capability to identify Pit Bull Terrier types from other similar dog types. Identification of both banned breeds, F(1, 20) = 57.746, p < .001, and bull breeds, F(1, 20) = 9.293, p = .006, was significantly lower than identification of other breeds. Recognition of Pit Bull Terrier types from similar types of dogs was generally poor, although people in a dog-related profession, as opposed to those in other professions, could correctly distinguish more pit bull-type dogs (U = 46,164.0, n₁ = 187, n₂ = 575, p = .003). Findings suggest public understanding of dangerous dogs is poor, and it may impact societal perceptions of dogs more widely.     

The Effect of Familiarity on Behavior of Kenneled Dogs During Interactions With Conspecifics

Kenneled environments often prevent direct physical contact between dogs, potentially causing stress, and so it has been recommended that such contact should be provided. This study examined the effect of familiarity on the behavior of dogs during off-lead interaction. Kenneled dogs (3 breeds) were given 15-min off-lead interactions with a familiar dog and an unfamiliar dog; the behavior of the focal dog and the distance between the dogs were recorded. More time in contact and interaction behaviors were recorded at 0 to 3 min with unfamiliar dogs than with familiar dogs. At 9 to 12 min, familiar pairs spent more time within 5 body lengths and more time being followed than unfamiliar pairs, who spent more time at more than 5 body lengths apart. This suggests that the initial interaction is more important when dogs are unfamiliar, but once this “greeting” has occurred, unfamiliar pairs are more likely to investigate their surroundings independently rather than together. Breed differences were observed only at 0 to 3 min. The study suggests that familiarity should be taken into account when assessing the effectiveness of conspecific contact as a potential enrichment for kennel-housed dogs.     

Poor prognosis of acute lymphoblastic leukaemia in Asian children living in the United Kingdom.

A study of the results of treatment of acute lymphoblastic leukaemia in Asian (Indian and Pakistani) children living in the United Kingdom showed that they had a poorer prognosis than native white children due mainly to deaths during remission. Similar proportions of Asian and white children suffered relapse. Lower socioeconomic status, poor nutrition, and difficulties in communication may have contributed to the worse outcome in the Asian children.     

Audit of prenatal diagnosis for haemoglobin disorders in the United Kingdom: the first 20 years.

OBJECTIVES: To audit services for prenatal diagnosis for haemoglobin disorders in the United Kingdom. DESIGN: Comparison of the annual number of cases recorded in a United Kingdom register of prenatal diagnoses for haemoglobin disorders, with the annual number of pregnancies at risk of these disorders, by ethnic group and regional health authority. The number of pregnancies at risk was estimated using data on ethnic group from the 1991 census and data from the United Kingdom thalassaemia register, which records the number of babies born with thalassaemia. SETTING: The three national prenatal diagnosis centres for haemoglobin disorders. SUBJECTS: 2068 cases of prenatal diagnosis for haemoglobin disorders in the United Kingdom from 1974 to 1994. MAIN OUTCOME MEASURES: Utilisation of prenatal diagnosis by risk, ethnic group, and regional health authority. Proportion of referrals in the first trimester and before the birth of any affected child. RESULTS: National utilisation of prenatal diagnosis for haemoglobin disorders was around 20%. During the past 10 years it has remained steady at about 50% for thalassaemias and risen from 7% to 13% for sickle cell disorders. Utilisation for sickle cell disorders varies regionally from 2% to 20%. Utilisation for thalassaemias varies by ethnic group. It is almost 90% for Cypriots and ranges regionally for British Pakistanis from 0% to over 60%. About 60% of first prenatal diagnoses are done for couples without an affected child. Less than 50% of first referrals are in the first trimester. CONCLUSIONS: National utilisation of prenatal diagnosis for haemoglobin disorders is far lower than expected, and there are wide regional variations. A high proportion of referrals are still in the second trimester and after the birth of an affected child. The findings point to serious shortcomings in present antenatal screening practice and in local screening policies and to inadequate counselling resources, especially for British Pakistanis.     

Malaria in the United Kingdom

Over the past decade the United Kingdom had the second highest number of cases of imported malaria among European countries. There has been a substantial rise in recorded cases of malaria during the past three years though some of it may be due to improved notification. Fatal cases of malaria in visitors to Africa have averaged 6.5% of reported infections due to Plasmodium falciparum. Attacks of vivax malaria may occur several months after travellers return from a malarious country.     

Imported Malaria in the United Kingdom

Over 2,000 cases of imported malaria have been confirmed by blood examination. Ninety percent. of cases from tropical Africa were infected with P. falciparum. Most of the patients were Caucasians and had primary infections. All developed fever within a month after arrival and most of them within two weeks of arrival. In some patients malaria parasites were seen in routine blood films.Developing forms of P. falciparum were always present in the peripheral blood of patients suffering from a primary attack which was not diagnosed or treated until a week or more after the onset of fever.All deaths investigated were caused by P. falciparum and were primary infections.In not one of the P. falciparum infections did the victim continue taking prophylactic drugs for more than a few days after leaving the endemic area. Had drugs been continued for one month probably not a single overt case of P. falciparum would have occurred.A primary attack of P. falciparum malaria is seldom, if ever, classical in that the fever is never tertian and may resemble clinically many other diseases.Children in boarding-schools returning from the tropics should be supplied with prophylactic tablets and instructions to the matron. If there is an epidemic of a fever any students who have recently returned from the tropics should have a blood film examined for malaria.The risk of contracting malaria among drug addicts is considerable, especially with P. falciparum.     

An Analysis of the Photosynthesis and Productivity of Vegetative Crops in the United Kingdom

The rate of total dry matter production of a vegetative crop,under optimal water and nutrient regimens is related to someleaf and canopy photosynthetic characteristics. Three leaf photosyntheticcharacteristics are examined in detail: the light utilizationefficiency at normal ambient CO₂ and O₂ concentrations, a, therate of light saturated photosynthesis per unit leaf area, F_max,and the ratio of the rates of photorespira tion and gross photosynthesis.The genetic variability in each of these characteristics issought from published data on a wide range of C₃ and C₄ planttypes. Within C₃ and C₄ plant types there are significant genetic differencesonly in F_max,, although differences exist between C₃ and C₄plants in the other two characteristics. The effects of thesedifferences on the rate total dry matter production are estimated,and it is concluded that there is no compelling evidence toindicate that improvements in total dry matter production rates,in the U.K., are likely to result from genetic manipulationof these characteristics in the existing range of plant material.