共查询到20条相似文献,搜索用时 15 毫秒
1.
Thanatip Ruksilp Jirapast Sichaem Suttira Khumkratok Pongpan Siripong Santi Tip-pyang 《Biochemical Systematics and Ecology》2011,39(4-6):888-892
Highlights? This is the first report on the phytochemical investigation of Morinda pandurifolia. ? A new natural anthraquinone (8) has been isolated from M. pandurifolia. ? Ten anthraquinones and iridoid glycoside have never been reported in this plant. ? Compounds 2, 3 and 4 showed moderate cytotoxicity against KB cells. 相似文献
2.
Senegenic acid (1) and senegenin (2) were transformed by Mucor polymorphosporus AS 3.3443. Four previously unreported metabolites were obtained. 相似文献
3.
Hu-Qiang Li Xiao-Jun Li You-Lin Wang Qiang Zhang An-Ling Zhang Jin-Ming Gao Xing-Chang Zhang 《Biochemical Systematics and Ecology》2011,39(4-6):876-879
From the culture of an endophyte Chaetomium globosum found in Ginkgo biloba, twelve metabolites, including three diketopiperazines, two cytochalasins, two sterols, two simple phenolic compounds, one complex aromatic compound, a nonprotein amino acid and a linear triterpene were isolated. Of them, eight compounds are first reported for the genus Chaetomium. Gliotoxin (8) has good antifungal activity against plant pathogenic fungi.Highlights? Twelve compounds were isolated from an endophyte C. globosum harboring inside G. biloba leaves. ? Eight compounds are new for the genus Chaetomium. ? Gliotoxin (8) possessed good antifungal activity against some phytopathogenic fungi. 相似文献
4.
Katharina Schiessl Swathi Kausika Paul Southam Max Bush Robert Sablowski 《Current biology : CB》2012,22(19):1739-1746
Highlights? JAGGED (JAG) is required for growth of initiating floral organs in Arabidopsis ? JAG decouples cell cycle from cell growth during organ emergence ? JAG promotes fast, anisotropic growth when floral organs emerge from the meristem ? JAG directly represses meristem identity genes 相似文献
5.
Aaron Ehlinger Soyeon Park Amr Fahmy Jeffrey W. Lary James L. Cole Daniel Finley Kylie J. Walters 《Structure (London, England : 1993)》2013,21(5):753-765
Highlights? Proteasome ATPase Rpt6 undergoes helix-coil exchange in its C-terminal domain ? Rpt6 G360,387A has a stabilized four-helix bundle and raised melting temperature ? Assembly chaperone Rpn14 binds selectively to the four-helix bundle Rpt6 conformer ? Rpt6 G360,387A (rpt6AA) is synthetically defective with an rpn14 null mutation 相似文献
6.
Highlights? Bacteriophytochrome structure containing photosensory and output transducing domain ? RpBphP1 binds to the cognate repressor RpPpsR2 on illumination with far-red light ? HOS domain is distantly related to Dhp and is essential for binding to the repressor ? Light-induced protomer swapping mechanism between dimers 相似文献
7.
Kirchdoerfer RN Herrin BR Han BW Turnbough CL Cooper MD Wilson IA 《Structure (London, England : 1993)》2012,20(3):479-486
Highlights? VLRBs use their C-terminal LRRs and the LRRCT-loop to interact with antigen ? Sequence-related VLRBs exhibit differential recognition of their BclA epitopes ? VLR4 binds a conserved protein epitope, yet is specific for B. anthracis spores 相似文献
8.
Caiyong Chen Daniel Garcia-Santos Yuichi Ishikawa Alexandra Seguin Liangtao Li Katherine H. Fegan Gordon J. Hildick-Smith Dhvanit I. Shah Jeffrey D. Cooney Wen Chen Matthew J. King Yvette Y. Yien Iman J. Schultz Heidi Anderson Arthur J. Dalton Matthew L. Freedman Paul D. Kingsley James Palis Barry H. Paw 《Cell metabolism》2013,17(3):343-352
Highlights? Snx3 is highly expressed in vertebrate hematopoietic tissues ? Silencing of Snx3 results in anemia and hemoglobin defects in vertebrates ? Snx3 and Vps35 physically interact with Tfrc ? Snx3 is required for endosomal recycling of Tf-Tfrc complex 相似文献
9.
Xiao-Qi Zhang Ye-Cai Lai Lei Wang Fang-Fang Xu Mei-Hua Gao Hua Li Yao-Lan Li Wen-Cai Ye 《Biochemical Systematics and Ecology》2011,39(4-6):861-863
Highlights? Acanthopanax senticosus yielded a wide array of phenylpropanoids. ? The first report to isolate tetrahydrofuran and bibenztetrahydronaphthalene type lignans from the genus Acanthopanax. ? The absolute configurations of these compounds were identified by a CD measurement for the first time. ? The composition of the lignans suggests a close relationship between genera Acanthopanax and Oplopanax. 相似文献
10.
Kelly L. Shea Wanyi Xiang Vincent S. LaPorta Jonathan D. Licht Charles Keller M. Albert Basson Andrew S. Brack 《Cell Stem Cell》2010,6(2):117-129
Highlights? Pax7+ skeletal satellite cells regenerate muscle in their endogenous environment ? Quiescent satellite cells express the RTK inhibitor Spry1 ? Spry1 is needed for satellite cells to return to quiescence after muscle injury ? Deletion of Spry1 in satellite cells depletes the muscle stem cell pool 相似文献
11.
Highlights? Trachea-derived Dpp/Bmp is required for midgut homeostasis ? Dpp expressed in tracheal cells reach intestinal cells through visceral muscles ? Dpp signaling is activated in enterocytes (ECs) in the Drosophila adult midgut ? Dpp signaling stabilizes ECs to restrict intestinal stem cell proliferation 相似文献
12.
Sophie Herszterg Andrea Leibfried Floris Bosveld Charlotte Martin Yohanns Bellaiche 《Developmental cell》2013,24(3):256-270
Highlights? During cytokinesis, neighboring cells accumulate MyoII at the edges of the furrow ? MyoII nonautonomously sets the initial geometry of the daughter cell interface ? Neighboring membranes impede adherens junction (AJ) formation until a midbody forms ? Arp2/3-dependent actin accumulation in the dividing cell maintains AJ geometry 相似文献
13.
Ying Tian Lijun Yuan Ashley M. Goss Tao Wang Jifu Yang John J. Lepore Diane Zhou Robert J. Schwartz Vickas Patel Ethan David Cohen Edward E. Morrisey 《Developmental cell》2010,18(2):275-287
Highlights? Wnt2 is required for atrial and inflow tract morphogenesis ? Wnt2 regulates expansion of secondary heart field progenitors ? Defects in Wnt2?/? mutants can be rescued using Wnt signaling agonists ? Wnt2 cooperates with Gata6 to regulate cardiac inflow tract development 相似文献
14.
Yuneva MO Fan TW Allen TD Higashi RM Ferraris DV Tsukamoto T Matés JM Alonso FJ Wang C Seo Y Chen X Bishop JM 《Cell metabolism》2012,15(2):157-170
Highlights? MYC and MET affect glucose and glutamine metabolism differently in the liver ? Tissue context affects the outcome of metabolic reprogramming by MYC ? MYC overexpression sensitizes cells to inhibition of Gls1 glutaminase 相似文献
15.
De Rybel B Vassileva V Parizot B Demeulenaere M Grunewald W Audenaert D Van Campenhout J Overvoorde P Jansen L Vanneste S Möller B Wilson M Holman T Van Isterdael G Brunoud G Vuylsteke M Vernoux T De Veylder L Inzé D Weijers D Bennett MJ Beeckman T 《Current biology : CB》2010,20(19):1697-1706
Highlights? GATA23 is involved in lateral root founder cell specification ? A coordinated migration of pericycle nuclei precedes the first asymmetric division ? An Aux/IAA28-dependent auxin signaling cascade controls GATA23 expression 相似文献
16.
Stelter M Gutsche I Kapp U Bazin A Bajic G Goret G Jamin M Timmins J Terradot L 《Structure (London, England : 1993)》2012,20(3):554-564
Highlights? Crystal structure of the ATPase domain of DnaB from Helicobacter pylori ? MALLS analysis shows that HpDnaB forms dodecamers ? EM reconstruction shows that HpDnaB forms head-to-head double hexamers 相似文献
17.
Klf15 orchestrates circadian nitrogen homeostasis 总被引:1,自引:0,他引:1
Jeyaraj D Scheer FA Ripperger JA Haldar SM Lu Y Prosdocimo DA Eapen SJ Eapen BL Cui Y Mahabeleshwar GH Lee HG Smith MA Casadesus G Mintz EM Sun H Wang Y Ramsey KM Bass J Shea SA Albrecht U Jain MK 《Cell metabolism》2012,15(3):311-323
Highlights? Nitrogen homeostasis exhibits circadian rhythmicity in mammals ? Klf 15 regulates rhythmic amino acid utilization and ammonia detoxification ? Krüppel-like factor 15 is regulated by the circadian clock ? Feeding is a major external cue regulating Klf15 rhythmicity and nitrogen homeostasis 相似文献
18.
Shang-Hua Zhai Ya-Nan Lu Cheng-Qi Fan Sheng-Nan Shao 《Biochemical Systematics and Ecology》2011,39(2):161-162
Highlights? Ascidia longistriata was collected for secondary metabolites investigation. ? This is the first report of compounds 1-3 from ascidians of the genus Ascidia. ? Compound 2 might be derived from an associated organism. 相似文献
19.
20.
Andersson CS Lundgren CA Magnúsdóttir A Ge C Wieslander A Martinez Molina D Högbom M 《Structure (London, England : 1993)》2012,20(6):1062-1070
Highlights? M. tuberculosis FadD13 is a peripheral membrane protein ? Mutagenesis reveals an arginine-rich patch as the site for membrane interaction ? A hydrophobic tunnel extends from the active site to the positively charged patch ? The architecture lets substrates reside partly in the membrane during catalysis 相似文献