Ectogenesis and the case against the right to the death of the foetus

Ectogenesis, or the use of an artificial womb to allow a foetus to develop, will likely become a reality within a few decades, and could significantly affect the abortion debate. We first examine the implications for Judith Jarvis Thomson’s violinist analogy, which argues for a woman’s right to withdraw life support from the foetus and so terminate her pregnancy, even if the foetus is granted full moral status. We show that on Thomson’s reasoning, there is no right to the death of the foetus, and abortion is not permissible if ectogenesis is available, provided it is safe and inexpensive. This raises the question of whether there are persuasive reasons for the right to the death of the foetus that could be exercised in the context of ectogenesis. Eric Mathison and Jeremy Davis have examined several arguments for this right, doubting that it exists, while Joona Räsänen has recently criticized their reasoning. We respond to Räsänen’s analysis, concluding that his arguments are unsuccessful, and that there is no right to the death of the foetus in these circumstances.     

Reexamining the Prohibition of Gestational Surrogacy in Sunni Islam

Advances in reproductive medicine have provided new, and much needed, hope for millions of people struggling with infertility. Gestational surrogacy is one such development that has been gaining popularity with infertile couples, especially those unable to benefit from other reproductive procedures such as In Vitro Fertilization. For many Muslim couples, however, surrogacy remains a nonviable option. Islamic scholars have deemed the procedure incompatible with Islam and have prohibited its use. This paper examines the arguments presented for proscribing surrogacy arrangements in Sunni Islam in particular. These include preservation of lineage, exclusion of third parties in reproduction, upholding the rights of the child, and protection from the negative effects of surrogacy arrangements. The rationales for banning surrogacy are subsequently refuted utilizing Islamic law “Sharia”, bioethics, and medical evidence. The paper also presents reasons for why surrogacy is not only consistent with Sunni Islamic teachings, but is also both ethically justified and medically necessary. Lastly, Islamic scholars are urged to take into account the arguments presented in this paper and reconsider their rulings on the permissibility of surrogacy.     

Ectogenesis,abortion and a right to the death of the fetus

Many people believe that the abortion debate will end when at some point in the future it will be possible for fetuses to develop outside the womb. Ectogenesis, as this technology is called, would make possible to reconcile pro‐life and pro‐choice positions. That is because it is commonly believed that there is no right to the death of the fetus if it can be detached alive and gestated in an artificial womb. Recently Eric Mathison and Jeremy Davis defended this position, by arguing against three common arguments for a right to the death of the fetus. I claim that their arguments are mistaken. I argue that there is a right to the death of the fetus because gestating a fetus in an artificial womb when genetic parents refuse it violates their rights not to become a biological parent, their rights to genetic privacy and their property rights. The right to the death of the fetus, however, is not a woman's right but genetic parents’ collective right which only can be used together.     

Language oppression and resistance: the case of middle class latinos in the United States

The growth of the US latino population is a source of concern for many white Americans, who assert this means the death of the US way of life and the English language. This racialized rhetoric masks an attempt to maintain the pre-eminence of the language of the dominant group over latinos and thus helps whites to sustain their political-economic domination. Using interviews with seventy-two middle-class latinos in seven US states, we document five strategies employed by the whites in everyday interaction to discourage latinos’ heritage language use and resistance to such discrimination. Finally, we discuss ideological elements in US culture that hide the racism in these language struggles.     

Gestational surrogacy and the role of routine embryo screening: Current challenges and future directions for preimplantation genetic testing

Preimplantation genetic screening (PGS) is a component of IVF entailing selection of an embryo for transfer on the basis of chromosomal normalcy. If PGS were integrated with single embryo transfer (SET) in a surrogacy setting, this approach could improve pregnancy rates, minimize miscarriage risk, and limit multiple gestations. Even without PGS, pregnancy rates for IVF surrogacy cases are generally satisfactory, especially when treatment utilizes embryos derived from young oocytes and transferred to a healthy surrogate. However, there could be a more general role for PGS in surrogacy, since background aneuploidy in embryos remains a major factor driving implantation failure and miscarriage for all infertility patients. At present, the proportion of IVF cases involving GS is limited, while the number of IVF patients requesting PGS appears to be increasing. In this report, the relevance of PGS for surrogacy in the rapidly changing field of assisted fertility medicine is discussed. Birth Defects Research (Part C) 108:98–102, 2016. © 2015 Wiley Periodicals, Inc.     

Experimental Sociality and Gestational Surrogacy in the Indian ART Clinic

Abstract

This article marks experimental modes of sociality in a transnational Indian assisted reproductive technology (ART) clinic as a contact zone between elite doctors, gestational surrogates, and transnational commissioning parents. It examines efforts within one ART clinic to separate social relationships from reproductive bodies in its surrogacy arrangements as well as novel social formations occurring both because of and despite these efforts. Draft regulative legislation in India marks a shift in the distribution of risk among actors in the clinic that parallels a shift in medical practice away from a technique of caring for the body to producing bodies as instruments of contracted service. The clinic provides an opportunity to observe forms of sociality that emerge as experiments with modernities, with different relationships to the body and the social meaning of medicalized biological reproduction, and with understanding the role of the market and altruism in the practice of gestational surrogacy.     

Gender-based disparities East/West: rethinking the burden of care in the United States and Taiwan

When feminist bioethicists express concerns about health-related gender disparities, they raise considerations about justice and gender that traditional bioethicists have either not raised or raised somewhat weakly. In this article, I first provide a feminist analysis of long-term healthcare by and for women in the United States and women in Taiwan. Next, I make the case that, on average, elderly US and Taiwanese women fare less well in long-term care contexts than do elderly US and Taiwanese men. Finally, I explore some suggested practical remedies to reduce gender disparities in long-term care contexts.     

Ethical issues raised by uterus transplantation: A report from the People's Republic of China

The recent advances in assisted reproductive technology, such as hormonal stimulation, IVF, and intracytoplasmic sperm injection (ICSI), have made it possible to circumvent many causes of male and female factor infertility. However, uterine infertility is still considered an ‘‘unconditionally infertile’’ condition. Owing to the continued advances in organ transplantation, microvascular anastomosis techniques, and immunosuppressive medicine, the transplantation of organs is no longer restricted to the ones necessary for continued life. Quality-of-life enhancing types of transplantation, such as uterine transplantation, in recent years, have also entered the clinical arena. This undoubtedly brings new hope to such women, but also creates ethical challenges. Selection of the donor, the impact on the recipient and offspring, as well as challenges to moral and social norms are issues that cannot be ignored. In the present review, the ethical issues of transplantation of the uterus will be discussed in light of recent progress in the procedure.     

Assisted reproduction technologies and reproductive justice in the production of parenthood and origin: Uses and meanings of the co-produced gestation and the surrogacy in Brazil

This article examines the construction of parenthood, drawing on Brazilian cisgender, heterosexual, and homosexual couples' experiences in using assisted reproduction technologies (ART), particularly the surrogacy. For that purpose, we interviewed: 1) a lesbian woman who had her daughter through her partner's pregnancy, using ART with anonymous donor semen; 2) a gay man who, together with his partner, used a surrogacy service under contract via a specialised offshore agency; 3) a woman who was a surrogate, in Brazil, for her sister-in-law and brother who lived abroad and, from abroad, sent an embryo fertilised for surrogacy; 4) a woman who resorted to her sister-in-law in order to be a mother by surrogacy, with ovules from the woman herself fertilised with semen from her husband; and 5) the sister-in-law mentioned in 4), who acted as surrogate for her brother and his wife. These interviews made it possible to think about the discursive construction of the legitimacy of such parenthoods, as it is produced by access to, and manipulation and circulation of, reproductive technologies and persons. This biomedical management of bodies sets up a material and discursive circuit that, in turn, produces a complex web of personal, normative, legal, professional and market relationships, particularly with a view to construction of a parenthood anchored in a notion of biologically-constituted origin. In this respect, biological, affective and social bonds merge to produce a precise placement of who is the father and/or who is the mother, as well as who are the important others and how they are linked to the child in a broader web of parenthood.     

Taxonomic surrogacy in biodiversity assessments,and the meaning of Linnaean ranks

The majority of biodiversity assessments use species as the base unit. Recently, a series of studies have suggested replacing numbers of species with higher ranked taxa (genera, families, etc.); a method known as taxonomic surrogacy that has an important potential to save time and resources in assesments of biological diversity. We examine the relationships between taxa and ranks, and suggest that species/higher taxon exchanges are founded on misconceptions about the properties of Linnaean classification. Rank allocations in current classifications constitute a heterogeneous mixture of various historical and contemporary views. Even if all taxa were monophyletic, those referred to the same rank would simply denote separate clades without further equivalence. We conclude that they are no more comparable than any other, non‐nested taxa, such as, for example, the genus Rattus and the phylum Arthropoda, and that taxonomic surrogacy lacks justification. These problems are also illustrated with data of polychaetous annelid worms from a broad‐scale study of benthic biodiversity and species distributions in the Irish Sea. A recent consensus phylogeny for polychaetes is used to provide three different family‐level classifications of polychaetes. We use families as a surrogate for species, and present Shannon‐Wiener diversity indices for the different sites and the three different classifications, showing how the diversity measures rely on subjective rank allocations.     

Ectogestation ethics: The implications of artificially extending gestation for viability,newborn resuscitation and abortion

Recent animal research suggests that it may soon be possible to support the human fetus in an artificial uterine environment for part of a pregnancy. A technique of extending gestation in this way (“ectogestation”) could be offered to parents of extremely premature infants (EPIs) to improve outcomes for their child. The use of artificial uteruses for ectogestation could generate ethical questions because of the technology’s potential impact on the point of “viability”—loosely defined as the stage of pregnancy beyond which the fetus may survive external to the womb. Several medical decisions during the perinatal period are based on the gestation at which infants are considered viable, for example decisions about newborn resuscitation and abortion, and ectogestation has the potential to impact on these. Despite these possible implications, there is little existing evidence or analysis of how this technology would affect medical practice. In this paper, we combine empirical data with ethical analysis. We report a survey of 91 practicing Australian obstetricians and neonatologists; we aimed to assess their conceptual understanding of “viability,” and what ethical consequences they envisage arising from improved survival of EPIs. We also assess what the ethical implications of extending gestation should be for newborn and obstetric care. We analyze the concept of viability and argue that while ectogestation might have implications for the permissibility of neonatal life-prolonging treatment at extremely early gestation, it should not necessarily have implications for abortion policy. We compare our ethical findings with the results of the survey.     

Interference and the ideal free distribution: models and tests

We review the assumptions and predictions of five competitivedistribution models that predict how optimal foragers will bedistributed across resource patches when gains are reduced byinterference. This review revealed a number of previously ignoredpredictions and assumptions: in particular, there should beno change in relative patch use as competitor density changes.A new model is proposed in which interference results from thecosts of encounters with other foragers and where the gainson a patch are independent of the costs of interference. Thismodel predicts that as density increases, there will be increasedproportional use of lower-quality patches. Past empirical studiesof interference distributions are reanalyzed; none of the studiesprovides strong support for any of the existing ideal free-distributionmodels. We suggest that previous results are more consistentwith the predictions of our new model.     

Cytomegalovirus Infection of the Cervix Detected By Cytology and Histology: A Report of Five Cases

We present four cases of cytomegalovirus (CMV) infection detected by cervical cytology of asymptomatic young women. One patient who had undergone bone marrow transplantation was immunosuppressed, but no factors predisposing to CMV infection were identified in the other three patients. A cervical biopsy specimen from a fifth patient, who was also asymptomatic, demonstrated the locus of CMV infection to be in endocervical gland cells. Immunocytochemical and polymerase chain reaction studies on this biopsy specimen confirmed that the histological changes were caused by CMV. the finding of CMV-infected cells in cervical cytological or biopsy specimens is a rarity. Our observations in asymptomatic, non-immunocompromised women suggest their presence is an incidental finding, unlikely to have any clinical significance.     

The ideal and the feasible: physical constraints on evolution

The laws of physics and the properties of the physical environment impose constraints on evolution. Structures and processes that may be imagined cannot in some cases be evolved, because they are physically impossible. This paper explores the consequences of the particulate nature of matter and of light; of the wave nature of light and sound; of the laws of diffusion and heat exchange; of the mechanical properties of materials; of limits to aerodynamic and hydrodynamic performance; and of the behaviour of electricity.     

How to address the ethics of reproductive travel to developing countries: a comparison of national self-sufficiency and regulated market approaches

One of the areas of concern raised by cross-border reproductive travel regards the treatment of women who are solicited to provide their ova or surrogacy services to foreign consumers. This is particularly troublesome in the context of developing countries where endemic poverty and low standards for both medical care and informed consent may place these women at risk of exploitation and harm. We explore two contrasting proposals for policy development regarding the industry, both of which seek to promote ethical outcomes and social justice: While one proposal advocates efforts to minimize cross-border demand for female reproductive resources through the pursuit of national self-sufficiency, the other defends cross-border trade as a means for meeting the needs of vulnerable groups. Despite the conflicting objectives of the proposed strategies, the paper identifies common values and points of agreement between the two, including the importance of regulations to safeguard those providing ova or surrogacy services.     

Unravelling the drivers of aquatic communities using disparate organismal groups and different taxonomic levels

Bioassessment and monitoring methods should be as cost-efficient as possible. Limiting the number of sites is not a practical solution to face the financial challenges related to bioassessment. Hence, it is highly important to find inexpensive ways to assess and monitor human-impacted environments. Suggestions have been made to use coarser taxonomic levels because they require less expertise and time, or to use single surrogate taxonomic groups that indicate the overall state of ecosystems. In this study, we examined the level of within-taxon and cross-taxon congruence of aquatic bacterial, diatom and macroinvertebrate communities, while simultaneously assessing the chemical, physical and spatial drivers of community structure in these organismal groups. Our study area was an extensively sampled large lake system with high connectivity between sites. Thus, we ensured that spatial processes, if they existed, were well portrayed in our data. Our aim was to find out the taxonomic levels sufficient for the purposes of bioassessment and to detect possible surrogate taxonomic groups. We found that bacterial communities were best associated with pure effects of water chemistry, whereas diatom and macroinvertebrate communities were varyingly related to chemical, physical and spatial variables. Macroinvertebrates were the only group related to small-scale spatial variables, while bacteria and diatoms were associated with variables illustrating spatial relations among sites at large and intermediate scales. Overall, the three organismal groups were mainly related to different chemical parameters. Also, the three organismal groups showed only weak, if any, congruent patterns in their community structure. Thus, we do not recommend the use of only one biological group as a surrogate in bioassessment. However, we found that higher taxonomic levels of all three studied organismal groups could be used as surrogates for finer-level taxonomic assignments. Our findings are promising for the possible use of bacteria in future bioassessment and monitoring. Owing to the characteristics of very large lake systems, our findings may be applied to similarly highly connected ecosystems, such as marine coastal systems.     

Towards the ideal GMP: homologous recombination and marker gene excision

A mayor aim of biotechnology is the establishment of techniques for the precise manipulation of plant genomes. Two major efforts have been undertaken over the last dozen years, one to set up techniques for site-specific alteration of the plant genome via homologous recombination ("gene targeting") and the other for the removal of selectable marker genes from transgenic plants. Unfortunately, despite multiple promising approaches that will be shortly described in this review no feasible gene targeting technique has been developed till now for crop plants. In contrast, several alternative procedures have been established successfully to remove selectable markers from plant genomes. Intriguingly besides techniques relying on transposons and site-specific recombinases, recent results indicate that homologous recombination might be a valuable alternative for the excision of marker genes.     

Constructing difference and sameness: the politics of assimilation in London's Arab communities

Contemporary migration has spurred reconsideration of the theoretical concepts used to explain immigrant-host society relationships. Traditional conceptions of assimilation have been an important topic of debate. Some urban sociologists question whether timeworn assimilation models 'fit' contemporary circumstances. Others challenge assimilation theories on a more fundamental level, abandoning notions of 'group adaptation' and focusing instead on social difference and cultural identity. Thus far, there has been very little dialogue between different theoretical perspectives. I attempt to bridge this gap by conceptualizing assimilation as observable, material processes of accommodation of and conformity to dominant norms. Assimilation, in this respect, is profoundly political rather than ecological or 'natural', and is relevant across geographical and historical contexts. Drawing on interviews with Arab immigrants in London, I shall illustrate the ways in which the construction of sameness (as well as difference) is central to immigrant experiences.