共查询到20条相似文献,搜索用时 31 毫秒
1.
F. A. Swartjes 《人类与生态风险评估》2009,15(1):138-158
Calculations using seven European exposure models were performed for 20 different exposure scenarios. The objective of this article is to understand the variation in the resulting calculated human exposures due to soil contamination. To this purpose, the variation in calculated exposures has been compared with the variation in calculated concentrations in contact media and in the soil compartments and with the variation in the input parameters. This led to the conclusion that most of the variation in Exposure through soil ingestion is explained by differences in the input parameter average daily soil intake. When model-specific input parameters are used the variation in Exposure through crop consumption is explained by differences in the product of total consumption rate and fraction of total consumption rate that is home-grown. When standardized input parameters are used, this variation is comparable with the variation in Concentration in root vegetables and in Concentration in leafy vegetables. The variation in Exposure through indoor air inhalation is comparable with the variation in Concentration in indoor air. This suggests that the parameters that control the variation in Concentration in the indoor air, that is, surface and volume of the building and, to a lesser extent, ventilation frequency of the building, also control the variation in Exposure through indoor air inhalation. 相似文献
2.
Elizabeth Harmon 《Journal of human evolution》2009,56(6):551-559
Aside from use as estimates of body mass dimorphism and fore to hind limb joint size comparisons, postcranial elements have not often contributed to assessments of variation in Australopithecus africanus. Meanwhile, cranial, facial, and dental size variation is interpreted to be high or moderately high. Further, the cranial base and face express patterns of structural (shape) variation, which are interpreted by some as evidence for the presence of multiple species. Here, the proximal femur is used to consider postcranial size and shape variation in A. africanus. Original fossils from Makapansgat and Sterkfontein, and samples from Homo, Pan, Gorilla, and Pongo were measured. Size variation was assessed by comparing the A. africanus coefficient of variation to bootstrapped distributions of coefficient of variation samples for each taxon. Shape variation was assessed from isometrically adjusted shape variables. First, the A. africanus standard deviation of log transformed shape variables was compared to bootstrapped distributions of logged standard deviations in each taxon. Second, shape variable based Euclidean distances between fossil pairs were compared to pairwise Euclidean distance distributions in each reference taxon. The degree of size variation in the A. africanus proximal femur is consistent with that of a single species, and is most comparable to Homo and Pan, lower than A. afarensis, and lower than some estimates of cranial and dental variation. Some, but not all, shape variables show more variation in A. africanus than in extant taxa. The degree of shape difference between some fossils exceeds the majority of pairwise differences in the reference taxa. Proximal femoral shape, but not size, variation is consistent with high estimates of A. africanus cranial variation. 相似文献
3.
It has recently been shown that Daphnia can vary in the phosphorus (P)-content of their body tissues, but the relative importance of genetic versus environmental causes for this variation is unexplored. We measured variation in P-content (as % body mass) of Daphnia from eight lakes and conducted experiments to contrast three sources of variation: interspecific variation, clonal variation and phenotypic plasticity. Daphnia P-content decreased with increasing seston C:P ratio across lakes. This relationship reflected both inter- and intraspecific variation. Daphnia parvula and D. dubia exhibited high P-content and were found in shallow lakes with low C:P seston, whereas D. pulicaria had low P-content and was found in deep, stratified lakes having high C:P seston. Populations of D. dentifera spanned this lake gradient and exhibited P-content that was negatively related to seston C:P. Evidence for phenotypic plasticity came from experiments with D. pulicaria and D. dentifera collected from a lake with P-deficient seston and fed a P-sufficient diet in the laboratory. In addition, populations of D. dentifera differed in P-content even after 7 d of feeding on P-sufficient resources, suggesting within-species clonal variation. However, mesocosm experiments revealed broad and surprisingly continuous variation in the P-content of individual clones of D. pulex (range 1.54–1.05%) and D. mendotae (1.51–1.07%) over a gradient in dietary C:P. The broad range in P-content exhibited by individual clones, acclimated for generations, suggests that variation in Daphnia P-content from laboratory experiments needs to be interpreted with caution. These results also show that phenotypic variation in response to environment can be a larger source of variation in P-content than genetic differences within or among species. 相似文献
4.
Geographic distribution and multilocus organization of isozyme variation of rice (Oryza sativa L.) 总被引:5,自引:0,他引:5
Z. Li J. N. Rutger 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》2000,101(3):379-387
Genetic organization of isozyme variation in rice (Oryza sativa L.) was investigated based on 17 polymorphic isozyme loci using a sample of 511 accessions of worldwide origin. The genetic
diversity within the species was very high (H=0.36 with 4.82 alleles per locus), as compared with most selfing plant species.
Three diversity centers were detected for isozyme variation including South Asia, China and Southeast Asia. The accessions
were classified into three well-differentiated cultivar groups corresponding to the indica and japonica subspecies, and a new unnamed group. Variation within the cultivar groups accounted for 80% of the total isozyme variation.
Within-country variation accounted for 58% of the total variation while among-region and among-country variation within the
cultivar groups accounted for only 14% and 8% of the total variation. Analyses using log-linear models revealed that pronounced
non-random associations between and among alleles at many unlinked isozyme loci were organized in a non-hierarchical pattern,
and subspecific and macro-geographic differentiation was much more pronounced in multilocus phenotype frequencies than in
allelic frequencies at individual loci. These results suggest that selection on multilocus gene complexes was largely responsible
for the maintenance of the extensive isozyme variation within the species and the indica-japonica differentiation. Our results further suggest the independent domestication of indica and japonica, the dual origins of the indica rice from China and South Asia (India), and the differentiation of the ecotypes ’javanica’ and the ’temperate japonica’ within the japonica subspecies.
Received: 5 August 1999 / Accepted: 13 December 1999 相似文献
5.
K. Wolff S. H. Rogstad B. A. Schaal 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》1994,87(6):733-740
Three Plantago species were surveyed for within- and between-population variation at DNA sequences detected with the M13 minisatellite probe. The levels and patterns of variation detected by this probe correspond to those expected from the mating systems of the species. The highly-selfing species P. major has a relatively low variability of minisatellite sequences within populations and considerable differentiation between populations. The outcrossing species P. lanceolata exhibits higher minisatellite variability within populations and moderate differentiation between populations. P. coronopus, with a mixed mating system, has levels of variation intermediate between P. major and P. lanceolata. The levels of variation within and between populations corresponds, in general, to the levels of allozyme variation determined in an earlier study. Mating system and population structure appear to have a major influence on M13-detected fragment variation. 相似文献
6.
Geographical variation and the role of climate in leaf traits of a relict tree species across its distribution in China
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- Intraspecific trait variation and trait–climate relationships are crucial for understanding a species’ response to climate change. However, these phenomena have rarely been studied for tree species. Euptelea pleiospermum is a relict tree species with a wide distribution in China that offers a novel opportunity to examine such relationships.
- Here, we measured 13 leaf traits of E. pleiospermum in 20 sites across its natural distribution in China. We investigated the extent of trait variation at local and regional scales, and developed geographic and climate models to explain trait variation at the regional scale.
- We documented intraspecific trait variation among leaf traits of E. pleiospermum at local and regional scales. Five traits exhibited relatively high trait variation: leaf area, leaf density and three leaf economic traits (leaf dry matter content, specific leaf area [SLA] and leaf phosphorus concentration). Significant trait–geography correlations were mediated by local climate. Most leaf trait variation could be explained (from 24% to 64%) by geographic or climate variables, except leaf width, leaf thickness, leaf dry matter content and leaf length–width ratio. Latitude and temperature were the strongest predictors of trait variation throughout the distribution of E. pleiospermum in China, and temperature explained more leaf trait variation than precipitation. In particular, we showed that leaves had longer petiole lengths, higher SLA and lower densities in northern E. pleiospermum populations. We suggest that northern E. pleiospermum populations are adapting to higher latitudinal environments via high growth rate (higher SLA) and low construction investment strategies (lower leaf densities), benefitting northern migration.
- Overall, we demonstrate that intraspecific trait variation reflects E. pleiospermum response to the local environment. We call for consideration of intraspecific trait variation to examine specific climate response questions. In addition, provenance experiments using widely distributed species are needed to separate trait variation resulting from genetic differentiation and plastic responses to environmental change.
7.
Phenotypic variation can arise from differences in the protein coding sequence and in the regulatory elements. However, little is known about the contribution of regulatory difference to the expression divergence, especially the cis and trans regulatory variation to the expression divergence in intraspecific populations. In this study, we used two different yeast strains, BY4743 and RM11‐1a/α, to study the regulatory variation to the expression divergence between BY and RM under oxidative stress condition. Our results indicated that the expression divergence of BY and RM is mainly due to trans regulatory variations under both normal and oxidative stress conditions. However, cis regulatory variation seems to play a very important role in oxidative stress response in yeast because 36% of genes showed an increase in cis regulatory variation effect compared with 13% of genes that showed an increase in trans regulatory variation effect after oxidative stress. Our data also indicated that genes located on the longer arm of the chromosomes are more susceptible to cis variation effect under oxidative stress than genes on the shorter arm of the chromosomes. 相似文献
8.
C. W. Morden J. Doebley K. F. Schertz 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》1990,80(3):296-304
Summary A survey of allozyme variation among the spontaneous taxa of Sorghum section Sorghum was undertaken. Eight plants each of 90 accessions representing the diploid S. bicolor (ssp. arundinaceum and drummondii) and the tetraploids S. almum and S. halepense were analyzed for 17 enzyme systems encoded by 30 loci. Low levels of variation were found within and among accessions, although there was more variation than is typical of inbreeding species. We found an average of 3.2 alleles per locus in ssp. arundinaceum, with a mean expected heterozygosity for the accessions of 0.034 and total panmictic heterozygosity of 0.154. An analysis of the apportionment of genetic variation among accessions of ssp. arundinaceum indicated that 26% of the variation occurs within accessions and 74% among accessions. Cultivated sorghum contains far less allozymic variation than ssp. arundinaceum, its presumed progenitor. This is consistent with the prediction that cultivated sorghum experienced a loss of genetic variation during domestication. For the most part, cultivated sorghum contains a subset of the allozymes found in ssp. arundinaceum. Principal component analysis revealed continuous variation among the accessions and geographic regions, with accessions failing to segregate into discrete clusters. However, accessions of race virgatum of ssp. arundinaceum occupied one end of the continuum and were, in that sense, distinguished from the other accessions. Similarly, most accessions of S. halepense and S. almum occupied the central portion of the continuum. The allozymic data presented here are consistent with the hypothesized origin of S. halepense via autopolyploidy or segmental allopolyploidy. 相似文献
9.
We report results of karyotype analyses using nine species of Maianthemum from China. The species, except M. atropurpureum (with 2n=72), had 2n=36, and the results support the earlier suggestion that Maianthemum has x=18 with 2n=36 in most species. The species examined, however, showed marked differences in karyotype, particularly in the numbers of metacentric, submetacentric, and acrocentric chromosomes as well as in the number of satellites. In addition, we distinguished three different modes based on the number of clear gaps in chromosome length variation: unimodal, bimodal, and trimodal. The unimodal variation (with no gap) was found in M. dahuricum and M. atropurpureum, the bimodal variation (with one gap) in M. tatsienense, and the trimodal variation (with two gaps) in M. bifolium, M. forrestii, M. japonicum, M. henryi, M. purpureum, and M. lichiangense. In the trimodal variation, the positions of the two gaps may differ from species to species. In addition, the frequency of acrocentric chromosomes per complement was generally higher in the trimodal variation than in the unimodal and bimodal variations. Results of our analyses, which had not been clearly presented prior to this, may provide a better understanding of species evolution in the tribe Polygonatae. 相似文献
10.
An analysis is made of the variation among individuals in finite populations of the proportion of their genes which are identical by descent. There are two causes of this variability: variation in pedigree among individuals, and linkage which causes whole blocks of genes to be identical or nonidentical by descent. The variation between and within populations is analyzed in detail for several mating systems: monoecious populations with and without random selfing, and dioecious populations with and without a hierarchical mating structure. Transition matrices for two-locus descent measures are given for each system. Total variability is obtained by integrating these measures over the distribution of map distances over whole chromosomes. Approximate methods are also developed for unlinked loci. Unless populations have a very small effective size (Ne) there is little variation in inbreeding between populations. For unlinked loci, the coefficient of variation in nonidentity within populations approaches about 1/√3Ne for random selfing, 1/√6Ne for monogamous matings and 1/√12Ne for monoecy with selfing excluded or dioecy with random pairing. If there is no association between map distance and initial heterozygosity or effect on quantitative traits, the coefficient of variation in mean heterozygosity over the genome is related to that in nonidentity, and the additional variation in a quantitative trait due to dominant genes equals the product of the square of the initial inbreeding depression and the squared coefficient of variation of nonidentity. 相似文献
11.
Low levels of intraspecific genetic variation at a rapidly evolving chloroplast dna locus in North American duckweeds (Lemnaceae) 总被引:1,自引:0,他引:1
Although most previous studies on chloroplast (cp) DNA variation in plants have concentrated on systematics and evolution above the species level, intraspecific variation in cpDNA is common and has provided useful insights into population-level evolutionary processes. Polymerase chain reaction methods were used to examine restriction site and sequence variation in the chloroplast rpLI6 gene within and among populations of duckweed species (Spirodela and Lemna) from the southern and eastern United States. To our knowledge, the rpL16 region has not previously been used to investigate cpDNA variation in nature. While considerable restriction site and sequence variation were detected among species, no variation was found within populations of either of the two species (S. punctata and L. minor) selected for sequence analysis, and S. punctata showed no interpopulational variation. Two cpDNA haplotypes were identified in L. minor, with one haplotype restricted to three sites in Louisiana and the other found in all other populations sampled. This paucity of variation cannot be readily explained as the result of a low mutation rate. In general, group II introns appear to be subject to very little functional constraint, and extensive sequence differences have been found between species in the chloroplast rpL16 intron in particular. However, factors such as historical range expansions and contractions, founding effects, fluctuations in local population size, and natural selection may play a role in reducing cpDNA sequence variability in these species. 相似文献
12.
Fimbriae or pili are essential adherence factors usually found in pathogenic bacteria to aid colonization of host cells.
Three major structural pilin genes, fimA, sfaA, and papA, from Escherichia coli natural isolates were examined and nucleotide sequence data revealed elevated levels of both synonymous and nonsynonymous
site variation at these loci. Examination of synonymous site variation shows a fivefold increase in fimA sites, relative to the housekeeping gene mdh; and similarly the sfaA and papA genes have increased synonymous sites variation relative to fimA. Nonsynonymous site variation is also elevated at all three loci but, in particular, at the papA locus (k
N= 0.44). The k
N/k
S ratio for the three genes are among the highest yet reported for E. coli genes. Regional variation in nucleotide polymorphism within each of the genes reveal hypervariable segments where nonsynonymous
substitutions exceed synonymous substitutions. We propose that at the fimA, papA, and sfaA genes, diversifying selection has brought about the increase levels of polymorphism.
Received: 7 August 1997 / Accepted: 8 March 1998 相似文献
13.
1. The stable carbon isotope ratio δ13C is a useful tracer of energy flow in lake food webs, and the zooplankton signature is commonly used to establish a baseline for the pelagic habitat. However, sources of temporal variability in the δ13C of different zooplankton taxa are rarely considered. 2. Here, we investigate to what extent temporal variation in the δ13C of particulate organic matter (POM) (<41 μm) and the C : N of zooplankton can explain the temporal variability in δ13C of freshwater zooplankton. We compare temporal patterns of δ13C and C : N for Daphnia, Hesperodiaptomus franciscanus and Leptodiaptomus tyrelli over a 6‐month period at four sites in two oligotrophic lakes. 3. In all three taxa, seasonal variation in zooplankton C : N explained more of the variation in zooplankton δ13C than did the δ13C of POM. This suggests that variation in the lipid content of zooplankton can strongly influence temporal variation of δ13C in zooplankton. 4. Using these data, we evaluate procedures that estimate the δ13C of only the non‐lipid component of zooplankton. If zooplankton lipids are primarily dietary in origin, than extracting lipids or ‘normalising’δ13C based on C : N will exclude a major dietary source, and therefore may be inappropriate. 5. We conclude that temporal variation in body composition (C : N) of zooplankton can significantly influence the temporal variation of zooplankton δ13C signatures. 相似文献
14.
Three common alleles, ɛ
2
, ɛ
3
, and ɛ
4
, of the gene coding for apolipoprotein E (apoE) have been identified as predictors of interindividual variation in measures
of lipid and lipoprotein metabolism, and ultimately risk of coronary heart disease (CHD), within many populations. Here we
evaluated the utility of the geographic distribution of these alleles for prediction of interpopulation variation in average
level of serum total cholesterol and other traditional risk factors, and CHD mortality rate. We employed published estimates
of the relative frequencies of the three common apoE alleles, average levels of risk factors such as serum total cholesterol, systolic and diastolic blood pressure, body mass
index, smoking prevalence and CHD mortality rate for nine population-based samples of middle-aged males studied by the international
WHO MONICA Project. There was approximately a 10-fold difference between the highest and lowest CHD mortality rate. Of the
traditional risk factors, variation in the average level of serum total cholesterol was the best predictor (approximately
33%) of the observed interpopulation variation in estimates of CHD mortality rate (Pr=0.10). Variation in the relative frequency of the ɛ
4
allele predicted approximately 50% of interpopulation variation in average serum total cholesterol level (Pr=0.02) and 75% of the variation in CHD mortality rate (Pr=0.002) when information about variation in the other risk factors and the ɛ
2
andɛ
3
alleles is ignored. Furthermore, variation in the relative frequency of the ɛ
4
allele predicted approximately 40% of the variation in CHD mortality rate (Pr=0.02) after considering the contribution of variation in average serum total cholesterol level. Average serum total cholesterol
level was estimated to increase by 0.114 mmol/l (4.405 mg/dl), and CHD mortality rate by 24.5/100 000, for an increase of
0.01 in the relative frequency of the ɛ
4
allele. The predictive utility of the ɛ
2
andɛ
3
alleles was considerably less than that of the ɛ
4
allele. For the sample of populations considered, the geographic distribution of the apoE alleles can be a statistically significant predictor of interpopulation variation in both the average serum total cholesterol
level and CHD mortality rate. In particular, the ɛ
4
allele may confer valuable ecological risk information.
Received: 2 December 1997 / Accepted: 28 May 1998 相似文献
15.
《Plant Ecology & Diversity》2013,6(3-4):523-536
Background: Genetic differentiation in phenotypic traits is often observed among forest tree populations, but less is known about patterns of adaptive variation within populations. Such variation is expected to enhance the survival likelihood of extant populations under climate change. Aims: Scots pine (Pinus sylvestris) occurs over a spatially and temporally heterogeneous landscape in Scotland. Our goal was to examine whether populations had differentiated genetically in timing of bud flush in response to spatial heterogeneity and whether variation was also maintained within populations. Methods: Two common-garden studies, involving maternal families of seedlings from 21 native pinewoods, were established and variation in the trait was measured at the beginning of the second growing season. Results: Populations showed genetic differences in the trait correlated with the length of growing season at their site of origin, but the majority of variation was observed within populations. Populations also differed in their levels of variation in the trait; a pattern that may be influenced by spatial variation in the extent of temporal climate variability. Conclusions: Our findings suggest that populations have adapted to their home environments and that they also have substantial ability to adapt in situ to changes in growing season length. 相似文献
16.
为揭示小叶锦鸡儿(Caragana microphylla)天然居群叶形态性状的变异规律及其生态适应性特征,该研究以10个小叶锦鸡儿天然居群为对象,通过多重比较、巢式方差分析、相关性分析、聚类分析和主成分分析等方法,对7个叶形态性状进行分析。结果表明:(1)小叶锦鸡儿叶形态性状在居群内和居群间均存在极显著差异(P < 0.01),平均变异系数为10.13%,不同性状的变异幅度为6.23%~12.78%;平均叶形态性状的表型分化系数为43.62%,居群内变异(30.09%)大于居群间变异(24.91%),说明居群内是其叶形态性状变异的主要来源。(2)相关性分析表明,环境因子对小叶锦鸡儿的叶形态性状变异有很大的影响,在地理空间上主要呈现出沿海拔梯度的变异模式;主成分分析的结果显示,小叶宽、叶柄宽和叶柄长对小叶锦鸡儿叶形态变异起主导作用;利用欧式距离对小叶锦鸡儿居群进行UPGMA聚类分析结果显示,基于叶形态性状和环境因子可分别将小叶锦鸡儿10个居群分为3类和2类,Mantel检验结果表明,小叶锦鸡儿的叶形态性状变异不存在地理连续性。研究结果为小叶锦鸡儿的适应性进化和开发利用提供了理论依据。 相似文献
17.
BJÖRN ROGELL MARTIN EKLUND HANNA THÖRNGREN ANSSI LAURILA JACOB HÖGLUND 《Molecular ecology》2010,19(11):2229-2240
Although loss of genetic variation is frequently assumed to be associated with loss of adaptive potential, only few studies have examined adaptation in populations with little genetic variation. On the Swedish west coast, the northern fringe populations of the natterjack toad Bufo calamita inhabit an atypical habitat consisting of offshore rock islands. There are strong among‐population differences in the amount of neutral genetic variation, making this system suitable for studies on mechanisms of trait divergence along a gradient of within‐population genetic variation. In this study, we examined the mechanisms of population divergence using QST–FST comparisons and correlations between quantitative and neutral genetic variation. Our results suggest drift or weak stabilizing selection across the six populations included in this study, as indicated by low QST–FST values, lack of significant population × temperature interactions and lack of significant differences among the islands in breeding pond size. The six populations included in this study differed in both neutral and quantitative genetic variation. Also, the correlations between neutral and quantitative genetic variation tended to be positive, however, the relatively small number of populations prevents any strong conclusions based on these correlations. Contrary to the majority of QST–FST comparisons, our results suggest drift or weak stabilizing selection across the examined populations. Furthermore, the low heritability of fitness‐related traits may limit evolutionary responses in some of the populations. 相似文献
18.
Ravi Parkash Shamina Minakshi Vashist 《Journal of Zoological Systematics and Evolutionary Research》1994,32(1):64-72
Ten Indian geographical populations of D. melanogaster were assayed electrophoretically for Adh genic variation. The Indian geographical populations of D. melanogaster revealed significant clinal variation (3 % for 1 d? latitude) at Adh locus and AdhF allelic frequency correlated significantly with increase in latitude. It was suggested that the abundance of secondary alcohols in the southern Indian tropical and humid environment might exert selective pressure favouring higher frequency of AdhS allele. Patterns of ethanol utilization as well as ethanol tolerance were analyzed in larval and adult individuals of six geographical populations of D. melanogaster. Latitudinal variation in ethanol tolerance was observed in D. melanogaster populations from India. The parallel occurrence of latitudinal variation it Adh locus as well as ethanol tolerance in Indian geographical populations of D. melanogaster could be maintained by balancing natural selection varying spatially along the north-south axis of the Indian sub-continent. 相似文献
19.
For the purpose of phylogeographic study of lucidophyllous (evergreen broad-leaved) forests in Japan, we surveyed intraspecific chloroplast DNA (cpDNA) variation in 41 component species of such forests. Intraspecific cpDNA variations were detected in 14 species. In 15 species and one species group, 16 non-coding cpDNA regions were examined to find intraspecific sequence variation. The extent of variation in these regions was compared. The largest amount of intraspecific variation was detected in the rps16 region. A relatively large amount of intraspecific variation was detected in the petD-rpoA, rpl16, and trnL-F regions. It is suggested that these regions of cpDNA would be useful for detecting intraspecific variation in plant species, and could provide valuable information for various research purposes. 相似文献
20.
Judith A. Irwin Eleni Soumpourou Clare Lister Jan‐Dick Ligthart Sue Kennedy Caroline Dean 《The Plant journal : for cell and molecular biology》2016,87(6):597-605
Variation in flowering time and response to overwintering has been exploited to breed brassica vegetables that can be harvested year‐round. Our knowledge of flowering time control now enables the investigation of the molecular basis of this important variation. Here, we show that a major determinant of heading date variation in Brassica oleracea is from variation in vernalization response through allelic variation at FLOWERING LOCUS C.C2 (BoFLC4). We characterize two alleles of BoFLC.C2 that are both functional and confer a requirement for vernalization, but they show distinct expression dynamics in response to cold. Complementation experiments in Arabidopsis thaliana revealed that the allelic variation results from cis polymorphism at BoFLC.C2, which quantitatively influences the degree of cold‐induced epigenetic silencing. This results in one allelic variant conferring consistently later heading under both glasshouse and field conditions through reduced environmental sensitivity. Our results suggest that breeding of brassica varieties for commercially valuable variation in heading date has been achieved through the selection of cis polymorphism at FLC, similar to that underpinning natural variation in A. thaliana. This understanding will allow for the selection of alleles with distinct sensitivities to cold and robust heading dates under variable climatic conditions, and will facilitate the breeding of varieties more resistant to climate change. 相似文献