Structure of the type V-C CRISPR-Cas effector enzyme

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Structure of the miniature type V-F CRISPR-Cas effector enzyme

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Structural basis of target DNA recognition by CRISPR-Cas12k for RNA-guided DNA transposition

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Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells

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Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates

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Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4

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Structural basis for the initiation of COPII vesicle biogenesis

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Cas12n nucleases,early evolutionary intermediates of type V CRISPR,comprise a distinct family of miniature genome editors

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Vitamin B12 Regulates Glial Migration and Synapse Formation through Isoform-Specific Control of PTP-3/LAR PRTP Expression

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CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury

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A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression

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SALSA,a genetically encoded biosensor for spatiotemporal quantification of Notch signal transduction in vivo

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TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways

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Calcium Wave Promotes Cell Extrusion

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PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model

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Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade

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Sterile liver injury induces a protective tissue-resident cDC1-ILC1 circuit through cDC1-intrinsic cGAS-STING-dependent IL-12 production

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Co-adaptor driven assembly of a CUL3 E3 ligase complex

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Sequential oncogenic mutations influence cell competition

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The miniature CRISPR-Cas12m effector binds DNA to block transcription

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