Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism

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Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle Analysis

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FGF1 and insulin control lipolysis by convergent pathways

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FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance

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A local insulin reservoir in Drosophila alpha cell homologs ensures developmental progression under nutrient shortage

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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation

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Cardiometabolic health improvements upon dietary intervention are driven by tissue-specific insulin resistance phenotype: A precision nutrition trial

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Worksite-based intensive lifestyle therapy has profound cardiometabolic benefits in people with obesity and type 2 diabetes

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The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine

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CDK2 limits the highly energetic secretory program of mature β cells by restricting PEP cycle-dependent KATP channel closure

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The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice

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The cephalic phase of insulin release is modulated by IL-1β

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MiR-690, an exosomal-derived miRNA from M2-polarized macrophages,improves insulin sensitivity in obese mice

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KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis

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Behavioral state-dependent modulation of insulin-producing cells in Drosophila

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Postprandial Hypoglycemia in Patients after Gastric Bypass Surgery Is Mediated by Glucose-Induced IL-1β

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Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention

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Serotonergic neurons translate taste detection into internal nutrient regulation

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Insulin Treatment Is Associated with Increased Mortality in Patients with COVID-19 and Type 2 Diabetes

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Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis

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