共查询到20条相似文献,搜索用时 0 毫秒
1.
2.
3.
Huson DH Dezulian T Klöpper T Steel MA 《IEEE/ACM transactions on computational biology and bioinformatics / IEEE, ACM》2004,1(4):151-158
In practice, one is often faced with incomplete phylogenetic data, such as a collection of partial trees or partial splits. This paper poses the problem of inferring a phylogenetic super-network from such data and provides an efficient algorithm for doing so, called the Z-closure method. Additionally, the questions of assigning lengths to the edges of the network and how to restrict the "dimensionality" of the network are addressed. Applications to a set of five published partial gene trees relating different fungal species and to six published partial gene trees relating different grasses illustrate the usefulness of the method and an experimental study confirms its potential. The method is implemented as a plug-in for the program SplitsTree4 相似文献
4.
It is now quite well accepted that the evolutionary past of certain species is better represented by phylogenetic networks
as opposed to trees. For example, polyploids are typically thought to have resulted through hybridization and duplication,
processes that are probably not best represented as bifurcating speciation events. Based on the knowledge of a multi-labelled
tree relating collection of polyploids, we present a canonical construction of a phylogenetic network that exhibits the tree.
In addition, we prove that the resulting network is in some well-defined sense a minimal network having this property. 相似文献
5.
Phylogenetic test of the molecular clock and linearized trees 总被引:30,自引:7,他引:23
To estimate approximate divergence times of species or species groups with
molecular data, we have developed a method of constructing a linearized
tree under the assumption of a molecular clock. We present two tests of the
molecular clock for a given topology: two-cluster test and branch-length
test. The two-cluster test examines the hypothesis of the molecular clock
for the two lineages created by an interior node of the tree, whereas the
branch-length test examines the deviation of the branch length between the
tree root and a tip from the average length. Sequences evolving excessively
fast or slow at a high significance level may be eliminated. A linearized
tree will then be constructed for a given topology for the remaining
sequences under the assumption of rate constancy. We have used these
methods to analyze hominoid mitochondrial DNA and drosophilid Adh gene
sequences.
相似文献
6.
Pavlinov IIa 《Zhurnal obshche? biologii》2007,68(1):19-34
Any research activity is conducted within the framework of a cognitive situation which is defined by certain basic assumptions about ontology of the portion of the objective world under investigation. From the standpoint of the non-classical scientific epistemology, a part of that situation is constituted by personal knowledge which is formed by a set of thinking (cognitive) styles. The scholastic thinking existing in taxonomy and phylogenetics is considered as an example showing unavoidability of such styles in the natural history knowledge. It is initially rooted in the antic, mythological by its essence, persuasion of isomorphism between movements of the objective reality and of the mind. The instrumentalism entailed by scholastic thinking is based on the mythologeme according to which the "right method" par excellence can lead to the "right knowledge". That is why any disputes between different numerical methods of phylogenetic reconstructions are vain: their validity could be assessed not formally but within particular cognitive situations formed by particular basic models of the phylogenesis. Phylogenetic thinking is of the key importance in evolutionary biology and has great impact on various fields of biology based on it. It is pretty mythological because of non-observability of the phylogenesis: the latter is rather "thinked-in" in the objective world then is induced from the observed facts. It constitutes a part of the evolutionary thinking considering mainly macroevolutionary trends and stressing the initial causes in the structure of causal relations in the analyses of the diversity of organisms. The "tree thinking" of O'Hara is its rough operational equivalent. Relation between phylogenetic thinking and some other styles are considered, which are population, phenetic, typological, and epigenetic ("developmental" of O'Hara). Phylogenetic thinking makes it obliged inclusion of the initial causes in the explanatory models which underlie adaptive and functional peculiarities of organisms, as well as of the entire structure of the biodiversity. It manifests itself in such kind of models through uncovering the phylogenetic signal. This thinking style has great effect on understanding of the ontology of taxa and acknowledges the objective status of the phylogenetic pattern. It is intrinsically included in the argumentation schemes of constructional morphology, comparative phylogenetics. The central metaphor of the phylogenetics is the Tree of Life. Emagination of its unity and uniquiness is of naturphilosophical nature. From the contemporary epistemological standpoint, it should be considered as a generalization upon partial hypotheses of evolution of particular structures each corresponding to certain consideration aspect of the global phylogenesis. Acknowledging of multi-aspectness of the phylogenesis constitutes one of the important points of modern phylogenetic thinking. As different semogeneses are incompletely congruent, the Tree of Life is less certain than each of the initial hypotheses. Any attempt to make it more resolved would lead to its reduction to any of the particular semogenetic scheme (i.e. to a "gene tree") or to its "decay" into several trees each corresponding to a particular consideration aspect of the global Tree. 相似文献
7.
Systematists and comparative biologists commonly want to make statements about relationships among taxa that have never been collectively included in any single phylogenetic analysis. Construction of phylogenetic 'supertrees' provides one solution. Supertrees are estimates of phylogeny assembled from sets of smaller estimates (source trees) sharing some but not necessarily all their taxa in common. If certain conditions are met, supertrees can retain all or most of the information from the source trees and also make novel statements about relationships of taxa that do not co-occur on any one source tree. Supertrees have commonly been constructed using subjective and informal approaches, but several explicit approaches have recently been proposed. 相似文献
8.
Phylogenetic trees based on gene content 总被引:2,自引:0,他引:2
Comparing gene content between species can be a useful approach for reconstructing phylogenetic trees. In this paper, we derive a maximum-likelihood estimation of evolutionary distance between species under a simple model of gene genesis and gene loss. Using simulated data on a biological tree with 107 taxa (and on a number of randomly generated trees), we compare the accuracy of tree reconstruction using this ML distance measure to an earlier ad hoc distance. We then compare these distance-based approaches to a character-based tree reconstruction method (Dollo parsimony) which seems well suited to the analysis of gene content data. To simplify simulations, we give a formal proof of the well-known 'fact' that the Dollo parsimony score is independent of the choice of root. Our results show a consistent trend, with the character-based method and ML distance measure outperforming the earlier ad hoc distance method. AVAILABILITY: http://www.ab.informatik.uni-tuebingen.de/software/genecontent/welcome_en.html 相似文献
9.
Recent studies have detected phylogenetic signals in pathogen–host networks for both soil‐borne and leaf‐infecting fungi, suggesting that pathogenic fungi may track or coevolve with their preferred hosts. However, a phylogenetically concordant relationship between multiple hosts and multiple fungi in has rarely been investigated. Using next‐generation high‐throughput DNA sequencing techniques, we analyzed fungal taxa associated with diseased leaves, rotten seeds, and infected seedlings of subtropical trees. We compared the topologies of the phylogenetic trees of the soil and foliar fungi based on the internal transcribed spacer (ITS) region with the phylogeny of host tree species based on matK, rbcL, atpB, and 5.8S genes. We identified 37 foliar and 103 soil pathogenic fungi belonging to the Ascomycota and Basidiomycota phyla and detected significantly nonrandom host–fungus combinations, which clustered on both the fungus phylogeny and the host phylogeny. The explicit evidence of congruent phylogenies between tree hosts and their potential fungal pathogens suggests either diffuse coevolution among the plant–fungal interaction networks or that the distribution of fungal species tracked spatially associated hosts with phylogenetically conserved traits and habitat preferences. Phylogenetic conservatism in plant–fungal interactions within a local community promotes host and parasite specificity, which is integral to the important role of fungi in promoting species coexistence and maintaining biodiversity of forest communities. 相似文献
10.
Trooskens G De Beule D Decouttere F Van Criekinge W 《Bioinformatics (Oxford, England)》2005,21(19):3801-3802
Summary: TreeIllustrator is a user-friendly application to visualizeand customize phylogenetic trees. It has a broad range of functionsand capabilities, such as dragging of nodes, different treeshapes, zooming and searching capabilities, and support forlarge trees. It acts as a solution that integrates the specificityof visualizing phylogenetic trees and the customization optionsof a drawing program. It also contains a simple and effectivemethod that compares a custom tree with the Tree of Life, bydetecting incongruence. Availability: A free version is available online at http://nexus.ugent.be/geert/ Contact: wim.vancriekinge{at}ugent.be 相似文献
11.
Rusk N 《Nature methods》2010,7(11):869
The integration of quantitative proteomics and analysis by machine learning yields a refined list of proteins involved in chromosome function. 相似文献
12.
13.
We review the resources available to systematic biologists who wish to use computers to build classifications. Algorithm development is in an early stage, and only a few examples of integrated applications for systematic biology are available. The availability of data is crucial if systematic biology is to enter the computer age. 相似文献
14.
Information about conformational properties of a protein is contained in the hydrophobicity values of the amino acids in its primary sequence. We have investigated the possibility of extracting meaningful evolutionary information from the comparison of the hydrophobicity values of the corresponding amino acids in the sequences of homologous proteins. Distance matrices for six families of homologous proteins were made on the basis of the differences in hydrophobicity values of the amino acids. The phylogenetic trees constructed from such matrices were at least as good (as judged from their faithful reflection of evolutionary relationships), as trees constructed from the usual minimum mutation distance matrix. 相似文献
15.
Phylogenetic inference based on matrix representation of trees. 总被引:14,自引:0,他引:14
M A Ragan 《Molecular phylogenetics and evolution》1992,1(1):53-58
Rooted phylogenetic trees can be represented as matrices in which the rows correspond to termini, and columns correspond to internal nodes (elements of the n-tree). Parsimony analysis of such a matrix will fully recover the topology of the original tree. The maximum size of the represented matrix depends only on the number of termini in the tree; for a tree derived from molecular sequences, the represented matrix may be orders of magnitude smaller than the original data matrix. Representations of multiple trees (which may or may not have identical termini) can readily be combined into a single matrix; columns of discrete-character-state data can be added and, if desired, weighted differentially. Parsimony analysis of the resulting composite matrix yields a hybrid supertree which typically provides greater resolution than conventional consensus trees. Use of this method is illustrated with examples involving multiple tRNA genes in organelles and multiple protein-coding genes in eukaryotes. 相似文献
16.
The biology of fig trees and their associated animals 总被引:1,自引:0,他引:1
17.
Many questions in comparative biology require that new data be collected, either to build a comparative database for the first time or to augment existing data. Given resource limitations in collecting data, the question arises as to which species should be studied to increase the size of comparative data sets. By taking hypotheses, existing data relevant to the hypotheses, and a phylogeny, we show that a method of “phylogenetic targeting” can systematically guide data collection while taking into account potentially confounding variables and competing hypotheses. Phylogenetic targeting selects potential candidates for future data collection, using a flexible scoring system based on differences in pairwise comparisons. We used simulations to assess the performance of phylogenetic targeting, as compared with the less systematic approach of randomly selecting species (as might occur when data have been collected without regard to phylogeny and variation in the traits of interest). The simulations revealed that phylogenetic targeting increased the statistical power to detect correlations and that power increased with the number of species in the tree, even when the number of species studied was held constant. We also developed a Web‐based computer program called PhyloTargeting to implement the approach ( http://phylotargeting.fas.harvard.edu ). 相似文献
18.
微生物系统发育多样性及其保护生物学意义 总被引:13,自引:2,他引:11
近年来,分子系统发育分析方法,特别是rBNA基因同源性分析方法,在微生物多样性的研究中发挥着越来越重要的作用.它克服了传统的微生物分离培养方法的限制,极大地促进了人们对微生物多样性的理解.在遗传信息同源性分析基础上得出的微生物系统发育多样性为多样性的保护提供了新的视点.它不但可以作为微生物多样性评价的手段,而且为多样性保护中优先秩序的确定提供了依据.同时也为生物多样性保护确定了目标,即最大程度地保护系统发育关系中所包含的信息.本文对微生物系统发育多样性的特点及其保护生物学意义进行了简要评述. 相似文献
19.