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1.
Tohno Y Tohno S Mahakkanukrauh P Vaidhayakarn P Somsarp V Minami T Moriwake Y Azuma C 《Biological trace element research》2001,84(1-3):19-35
To elucidate compositional changes of arteries with aging, the authors previously investigated age-related changes of mineral
contents in the various arteries of Japanese and Japanese monkey. To examine whether there were differences between races
in regard to age-related changes of mineral contents and the relationships among element contents in the arteries, the authors
investigated the arteries of Thai. The subjects consisted of 13 men and 3 women, ranging in age from 39 to 84 yr. After the
ordinary dissection at Chiang Mai University was finished, abdominal aortas, common iliac, internal iliac, and external iliac
arteries were resected and the element contents were determined by inductively coupled plasma-atomic emission spectrometry.
The contents of calcium, phosphorus, and magnesium became the highest in the fifties in the abdominal aorta, common iliac,
and external iliac arteries, whereas the contents of calcium and magnesium became the highest in the sixties in the internal
iliac artery, and decreased thereafter. In regard to relationships among element contents, it was found that there were high
correlations between calcium and phosphorus contents, between calcium and magnesium contents, and between phosphorus and magnesium
in all of the abdominal aortas and three iliac arteries. The mass ratios of magnesium to calcium and phosphorus were each
similar in the abdominal aorta, common iliac, and internal iliac arteries, except for the external iliac artery, in which
it was slightly high. These revealed that as calcium and phosphorus increased in the arteries with aging, magnesium increased
in the arteries as well. The differences between the arteries of Thai and Japanese were discussed in the present article. 相似文献
2.
Tohno S Tohno Y Moriwake Y Azuma C Ohnishi Y Minami T 《Biological trace element research》2001,84(1-3):57-66
To elucidate the mechanism of element accumulations in the arteries with aging, the authors investigated the mass ratios among
calcium, phosphorus, and magnesium in the common iliac arteries by inductively coupled plasma-atomic emission spectrometry.
The subjects consisted of 16 men and 8 women, ranging in age from 65 to 93 yr.
It was found that there were extremely significant correlations between calcium and phosphorus contents, between calcium and
magnesium contents, and between phosphorus and magnesium contents in the common iliac arteries. In regard to the mass ratio,
although the mass ratio of calcium to phosphorus was almost constant, the mass ratios of magnesium to calcium and phosphorus
were different at early and advanced stages of the accumulation of calcium and phosphorus. It was found that both the mass
ratios of magnesium to calcium and phosphorus were higher at an early stage of the accumulation of calcium and phosphorus
in the arteries than at an advanced stage of the accumulation. 相似文献
3.
To examine whether an accumulation of elements in the arteries with aging differs between human and animal, the authors investigated
the relationships among element contents in the arteries of the Japanese monkeys. The Japanese monkeys consisted of five males
and four females, ranging in age from 2 to 29 yr. The aorta, common and external iliac, femoral, common carotid, subclavian,
and axillary arteries were resected from the monkeys and element contents were determined by inductively coupled plasma-atomic
emission spectrometry. It was found that there were very high correlations between calcium and phosphorus contents, between
calcium and magnesium contents, and between phosphorus and magnesium contents in all of the monkey arteries. In addition,
significant correlations were found among the other element contents in some, but not all of the arteries. These results were
consistent with the foregoing findings of the human arteries. It is likely that magnesium forms compounds with phosphorus
or calcium in the monkey arteries. 相似文献
4.
Mahakkanukrauh P Tohno S Sinthubau A Tohno Y Azuma C Minami T 《Biological trace element research》2006,112(1):43-56
To elucidate compositional changes of the cerebral arteries with aging, the authors investigated age-related changes of elements
in the cerebral arteries by inductively coupled plasma-atomic emission spectrometry (ICP-AES). After an ordinary dissection
by medical students at Chiang Mai University was finished, the anterior, middle, and posterior cerebral arteries and the anterior
and posterior communicating arteries were resected from the subjects. The subjects consisted of six men and seven women, ranging
in age from 34 to 86 yr. The element content was determined by ICP-AES. It was found that the Mg content increased progressively
with aging in all of the anterior, middle, and posterior cerebral arteries, but the Ca and P content did not increase significantly
with aging in the anterior, middle, and posterior cerebral arteries, with the one exception being that the P content increased
significantly in the posterior cerebral arteries with aging. The average content of Ca was higher in the order of the anterior
communicating, anterior cerebral, posterior communicating, posterior cerebral, and middle cerebral arteries. 相似文献
5.
Yoshiyuki Tohno Setsuko Tohno Yumi Moriwake Cho Azuma Yoshiaki Ohnishi Takeshi Minami 《Biological trace element research》2001,82(1-3):21-28
To elucidate compositional changes of the arteries with aging, the authors investigated the relationships among average contents
of calcium, phosphorus, sulfur, and magnesium in the arteries by inductively coupled plasma-atomic emission spectrometry.
The arteries used were the thoracic and abdominal aortas, coronary, common carotid, anterior, middle and posterior cerebral,
vertebral, basilar, internal thoracic, axillary, radial, truncus celiacus, common, internal and external iliac, femoral, popliteal,
and umbilical arteries. It was found that high correlations were found between the average contents of calcium and phosphorus,
between the average contents of calcium and magnesium, and between the average contents of phosphorus and magnesium in the
arteries, but not between the average contents of sulfur and the other elements. These correlations revealed that as the content
of calcium and phosphorus increased in the arteries, the magnesium content increased simultaneously in the arteries, but the
sulfur content did not. It is likely that magnesium forms compounds with phosphorus in the arteries. 相似文献
6.
Mahakkanukrauh P Tohno S Tohno Y Chomsung R Azuma C Moriwake Y Minami T 《Biological trace element research》2004,100(3):205-214
To examine whether there were differences between races in regard to the relationships among element contents in the arteries,
the authors investigated the relationships among the average contents of calcium, phosphorus, sulfur, and magnesium in the
18 kinds of the Thai artery. After ordinary dissection by medical students at Chiang Mai University was finished, the thoracic
and abdominal aortas, ramifying site of the abdominal aorta into the common iliac arteries, coronary, common carotid, internal
thoracic, subclavian, axillary, brachial, radial, superior and inferior mesenteric, renal, common iliac, internal iliac, and
external iliac arteries were resected from the subjects who consisted of 12 men and 3 women, ranging in age from 39 to 84
yr. The femoral and posterior tibial arteries were resected from the subjects, consisting of 15 men and 5 women, ranging in
age from 25 to 88 yr. The element content of the arteries was analyzed by inductively coupled plasma-atomic emission spectrometry.
It was found that there were extremely significant direct correlations among the average contents of calcium, phosphorus,
and magnesium in the 18 kinds of the Thai artery, but no significant correlations were found between the average contents
of sulfur and elements, such as calcium, phosphorus, and magnesium. These results were in agreement with those of the Japanese
arteries. Therefore, it was suggested that there was no significant difference between the arteries of the Thai and the Japanese
in the relationships among calcium, phosphorus, sulfur, and magnesium. 相似文献
7.
Tohno S Mahakkanukrauh P Tohno Y Vaidhayakarn P Minami T Somsarp V Moriwake Y Chomsung R Azuma C 《Biological trace element research》2002,87(1-3):69-82
To examine whether there were differences between races in regard to age-related changes of mineral contents and the relationships
among element contents in the arteries, the authors investigated the coronary arteries of Thai and Japanese. The Thai subjects
consisted of 13 men and 3 women, ranging in age from 39 to 84 yr, whereas the Japanese subjects consisted of 17 men and 9
women, ranging in age from 55 to 92 yr. After the ordinary dissections at Chiang Mai University and Nara Medical University
were finished, the coronary arteries were resected and the element contents were determined by inductively coupled plasma-atomic
emission spectrometry. In the Thai, an accumulation of calcium and phosphorus began to occur in the forties and increased
markedly in the fifties, whereas in the Japanese, an accumulation of calcium and phosphorus began to occur in the seventies
and increased markedly in the nineties. The result revealed that an accumulation of calcium and phosphorus occurred earlier
in the Thai than in the Japanese. Regarding the relationships among element contents, extremely significant correlations were
found between calcium and phosphorus contents, between calcium and magnesium contents, and between phosphorus and magnesium
contents in both the coronary arteries of the Thai and the Japanese. As far as the coronary arteries with a very high accumulation
of calcium and phosphorus, the mass ratios of magnesium to calcium and phosphorus were lower in the coronary arteries of the
Thai in comparison with the Japanese. 相似文献
8.
Yoshiyuki Tohno Setsuko Tohno Yumi Moriwake Cho Azuma Yoshiaki Ohnishi Takeshi Minami 《Biological trace element research》2001,82(1-3):9-19
To elucidate the accumulation of elements in the arteries with aging, the authors investigated age-related changes of elements
in human arteries, such as the thoracic aorta, femoral, basilar, coronary, radial, and common iliac arteries by inductively
coupled plasma-atomic emission spectrometry. The subjects consisted of 17 men and 9 women, ranging in age from 55 to 92 yr
in the cases of the five arteries, except for the common iliac arteries, in which the subjects consisted of 16 men and 8 women,
ranging in age from 65 to 93 yr.
It was found that there were significantly direct correlations between calcium and phosphorus contents and between calcium
and magnesium contents in all of the six arteries: thoracic aorta, femoral, basilar, coronary, radial, and common iliac arteries.
Significantly direct correlations were also found between phosphorus and magnesium contents in the five arteries, except for
the basilar artery. In contrast, significantly inverse correlations were found between calcium and sulfur contents and between
phosphorus and sulfur contents in the four arteries, except for the coronary and radial arteries. These revealed that the
accumulation of calcium and phosphorus in the arteries was accompanied by an increase of magnesium in the arteries and by
a decrease of sulfur in the arteries. 相似文献
9.
Tohno S Naganuma T Ongkana N Mahakkanukrauh P Tohno Y Azuma C Moriwake Y Minami T Maruyama H 《Biological trace element research》2007,116(2):111-118
To elucidate compositional changes of the uterine artery with aging, the authors investigated age-related changes of elements
in the uterine arteries. After ordinary dissection by medical students at Nara Medical University was finished, the uterine
arteries were resected from the subjects. The element content of the uterine arteries was analyzed by inductively coupled
plasma-atomic emission spectrometry. The subjects ranged in age from 58 to 99 yr (average age=82.7±10.1 yr). It was found
that the Ca, P, and Na contents increased progressively in the uterine arteries with aging. A significant accumulation of
Ca and P in the uterine arteries was found in the sixties and increased markedly in the eighties. It should be noted that
as far as the arteries in those over 70 yr of age, the extent of accumulation of Ca and P was the highest in the uterine arteries
within the limits of the arteries analyzed by us. Regarding the relationships among elements, significant direct correlations
were found among the contents of Ca, P, Mg, Zn, and Na. As Ca increased in the uterine arteries, P, Mg, Zn, and Na increased
simultaneously in the arteries. 相似文献
10.
Mahakkanukrauh P Tohno S Tohno Y Azuma C Ongkana N Moriwake Y Minami T 《Biological trace element research》2005,106(3):219-229
To examine whether there were differences between reces in regard to age-related changes of elements and the relationships
among elements in the arteries, the authors investigated both the renal arteries of Thai and Japanese. The Thai subjects consisted
of 27 men and 11 women, ranging in age from 27 to 88 yr, whereas the Japanese subjects consisted of 19 men and 26 women, ranging
in age from 61 to 99 yr. After the ordinary dissections at Chiang Mai University and Nara Medical University were completed,
the bilateral renal arteries were resected and the element contents were determined by inductively coupled plasma-atomic emission
spectrometry. In the Thai, a slight accumulation of calcium and phosphorus occurred in the fifties, but thereafter headly
increased. In contrast, in the Japanese, an accumulation of calcium and phosphorus began to occur in the seventies and increased
markedly in the eighties. The result reveraled that a higher accumulation of calcium and phosphorus occurred in the renal
arteries of the Japanese in old age compared with those of the Thai. Regarding the relationships among elements, extremely
or very significant direct correlations were found among the contents of calcium, phosphorus, magnesium, and sodium in both
the renal arteries of the Thai and Japanese, except for magnesium and sodium contents in the renal arteries of the Thai. 相似文献
11.
Azuma C Tohno S Mahakkanukrauh P Tohno Y Satoh H Chomsung R Minami T Moriwake Y Utsumi M Vaidhayakarn P 《Biological trace element research》2003,95(3):211-218
To analyze the accumulation of elements in the rami of the coronary arteries, the authors determined element contents in both
the coronary arteries and their rami of the Thai by inductively coupled plasma-atomic emission spectrometry. The subjects
consisted of 13 men and 6 women, ranging in age from 34 to 83 yr. It was found that a higher accumulation of calcium and phosphorus
occurred in the proximal sites of coronary arteries such as the anterior descending, right coronary, left coronary, and circumflex
arteries than the distal sites such as the diagonal, lateral, conus, acute marginal, and posterior descending arteries. The
accumulation of calcium and phosphorus in the anterior descending and right coronary arteries of the Thai increased remarkably
in the fifties, thereafter decreased, and increased again in the eighties. It should be noted that a very high accumulation
of calcium and phosphorus in the coronary arteries occurred in the fifties. In regard to relationships among the average contents
of elements in the coronary arteries and their rami, it was found that there were very significant direct correlations between
calcium and phosphorus contents, between calcium and magnesium contents, and between phosphorus and magnesium contents. These
results suggested that as calcium and phosphorus increased in the coronary arteries and their rami, magnesium increased simultaneously
in all of the coronary arteries and their rami. 相似文献
12.
Tohno S Tohno Y Hayashi M Minami T Moriwake Y Azuma C Ohnishi Y 《Biological trace element research》2003,95(2):173-184
To examine whether the calcium accumulation in aged arteries is related to the way of walking, the mineral contents were determined
in the arteries of Japanese monkeys of quadrupedal walk by inductively coupled plasma-atomic emission spectrometry. Sixteen
Japanese monkeys consisting of 7 males and 9 females ranging in age from 2 to 33 yr were studied.
The accumulation of calcium, phosphorus, and magnesium occurred progressively in most, but not all, of the arteries with aging.
It was found that independent of the upper and lower limbs, a higher accumulation of calcium, phosphorus, and magnesium occurred
in the arteries of the proximal regions with aging, compared with the arteries of the distal regions.
In a comparison between the arteries of anatomically corresponding regions of the upper and lower limbs, the accumulation
of calcium and magnesium was 20–60% higher in the external iliac and femoral arteries of the lower limb than in the axillary
and brachial arteries of the upper limb. Regarding phosphorus, the accumulation was 20–120% higher in the external iliac and
femoral arteries than in the axillary and brachial arteries. It was known that in humans, the accumulation of calcium, phosphorus,
and magnesium was three to seven times higher in the arteries of the lower limb than in the arteries of the upper limb. It
is clear that there is a very significant difference in the accumulation of calcium and magnesium in the arteries of the lower
limbs between Japanese monkeys and humans. The present study suggests that the accumulation of calcium and magnesium in the
arteries of the lower limb with aging is affected by the way of walking. 相似文献
13.
Tohno Y Tohno S Mahakkanukrauh P Azuma C Moriwake Y Ongkana N Kumai T Minami T Maruyama H 《Biological trace element research》2006,112(1):31-42
To explore reasons for a high accumulation of Ca and P occurring in the coronary artery of Thai with aging, the authors investigated
age-related changes of elements in the coronary artery, ascending aorta near the heart, and cardiac valves in single individuals,
and the relationships in the elements between the coronary artery and either the ascending aorta or cardiac valves. After
an ordinary dissection by medical students at Chiang Mai University was finished, the anterior descending arteries of the
left coronary artery, ascending aortas, mitral valves, and aortic valves were resected from the subjects. The subjects consisted
of 17 men and 9 women, ranging in age from 46 to 76 yr. The element content was analyzed by inductively coupled plasma-atomic
emission spectrometry. The average content of Ca and P was the highest in the coronary artery and decreased in the order aortic
valve, ascending aorta, and mitral valve. The Ca, P, and Mg content increased in the coronary artery in the fifties and in
the ascending aorta, aortic valve, and mitral valve in the sixties. It should be noted that the accumulation of Ca, P, and
Mg occurred earlier in the coronary artery than in the ascending aorta, aortic valve, and mitral valve. It was found that
with respect to the Ca, P, Mg, and Na contents, the coronary artery correlated well with both the aortic valve and ascending
aorta, especially with the aortic valve, but it did not correlate with the mitral valves. This finding suggests that the accumulation
of Ca, P, Mg, and Na occurs in the coronary artery together with the aortic valve and ascending aorta, but not together with
the mitral valve. Because regarding the accumulation of Ca, P, and Mg, the ascending aorta and aortic valve are preceded by
the coronary artery, it is unlikely that the accumulation of Ca, P, and Mg spreads from the ascending aorta or aortic valve
to the coronary artery. 相似文献
14.
At the heads of two river reservoirs, the Ishitegawa Dam and the Nomura Dam Reservoirs in Japan, the concentrations of phytoplanktonic particulate phosphorus (PP) were compared with those of dissolved calcium (Ca) and magnesium (Mg), using multiple regression analyses on the data taken from samples which registered more than 6.0 µg l–1 in chlorophyll a concentration. Of the 27 monthly samples, 16 from the Ishitegawa Reservoir and 17 from the Nomura Reservoir were used. A significant regression line, logPP = k
1F + k
2, was obtained, where k
1 (> 0) and k
2 were constants and F (named the Ca-Mg index) consisted of log(Ca/Mg) – 0.5 log(ca + Mg) in mol concentration in Ca and Mg, in common with the two reservoirs (r
2 = 0.730 & 0.913). 相似文献
15.
Setsuko Tohno Yoshiyuki Tohno Motoharu Hayashi Yumi Moriwake Takeshi Minami Fumio Nishiwaki Tsutomu Araki 《Biological trace element research》2001,82(1-3):77-86
To examine whether the calcium accumulation in the arteries is related to the way of walk or not, the calcium contents were
determined in various arteries of Japanese monkeys of quadrupedal walk by inductively coupled plasma-atomic emission spectrometry.
Japanese monkeys consisted of five males and four females, ranging in age from 2 to 29 yr.
Age-related changes of the calcium content were examined in various monkey arteries. Significant relationships between age
and calcium content were found in the arteries, such as the axillary, brachial, radial, subclavian, common carotid, common
iliac, and femoral arteries, but not statistically in the thoracic and abdominal aortas, ulnar, external iliac, internal iliac,
popliteal, and tibial arteries.
The average contents of calcium were compared between the two groups of the monkeys below 14 yr and over 24 yr of age. Below
14 yr, the calcium content was a little higher in the arteries, such as the common, external and internal iliac, and femoral
arteries than that of the other ones. Over 24 yr, the calcium content increased remarkably in the arteries, such as the thoracic
aorta, common, internal and external iliac, common carotid, and subclavian arteries. The calcium contents of the thoracic
aorta, common, internal and external iliac, common carotid, and subclavian arteries increased by more than two times over
24 yr compared with those below 14 yr.
In a comparison between the calcium contents of the arteries in the anatomically corresponding regions of the upper and lower
limbs, no statistically significant differences were found in the subjects over 24 yr as well as the subjects 2–29 yr of age.
The calcium accumulation in the arteries of monkeys with aging was different from those in the arteries of humans, because
in the case of human, a very high accumulation of calcium occurred in the arteries of the lower limb with aging in comparison
with those in the upper limbs.
Therefore, it is likely that different ways of walk or different species are partly affected in the calcium accumulation in
the arteries with aging. 相似文献
16.
Ongkana N Tohno S Payo IM Azuma C Moriwake Y Minami T Tohno Y 《Biological trace element research》2007,117(1-3):23-38
To elucidate whether the accumulation of elements occurred simultaneously in the various arteries with aging, the authors
investigated age-related changes of elements in the eight arteries, such as the thoracic and abdominal aortas and the coronary,
common carotid, pulmonary, splenic, common iliac, and uterine arteries, and the relationships in the element contents among
their arteries. After ordinary dissection by medical students was finished, the thoracic and abdominal aortas and the coronary,
common carotid, pulmonary, splenic, common iliac, and uterine arteries were resected from the subjects, who ranged in age
from 58 to 94 yr. The element contents were analyzed by inductively coupled plasma-atomic emission spectrometry. It was found
that the accumulation of Ca was the highest in the common iliac artery and decreased in the order of the uterine artery, abdominal
aorta, coronary artery, thoracic aorta, splenic artery, common carotid artery, and pulmonary artery. Regarding the relationships
in the element contents among the eight arteries, it was found that there were significant direct correlations in the contents
of Ca, P, Mg, Zn, Fe, and Na between the coronary and splenic arteries, and there were significant correlations in the contents
of Ca, P, and Mg between the abdominal aorta and pulmonary artery. 相似文献
17.
《Animal : an international journal of animal bioscience》2014,8(7):1080-1088
A total of 600 Ross 308-day-old male broiler chicks were used in a 28 day digestibility study to investigate the interaction between dietary calcium (Ca) and non-phytate phosphorus (nPP) on the digestibility of minerals and amino acids. Diets were formulated to be nutritionally adequate except for Ca and nPP. Fifteen mash diets based on corn and soya bean meal with varying concentrations of Ca (6.4 to 12.0 g/kg) and nPP (2.4 to 7.0 g/kg) were used. Diets were clustered around total densities of Ca and nPP of 12, 13.5 or 15.0 (g/kg) and within each density, a range of five Ca : nPP ratios (1.14 : 1, 1.5 : 1, 2.0 : 1, 2.75 : 1 and 4.0 : 1) were fed. Birds had free access to feed and water throughout the study. At day 28, birds were euthanised for the determination of apparent ileal mineral and amino acid digestibility. Data were modelled in R version 2.15 using a linear mixed-effects model and interrogation of the data was performed by fitting a low order polynomial function. At high Ca concentrations, increasing nPP led to an increase in the apparent digestibility of minerals. Apparent ileal digestibility of phosphorus (P) was enhanced with increasing dietary nPP up to 5.5 g/kg beyond which no improvements were found. Maximal Ca digestibility was found in diets with >8.0 g/kg Ca with concomitant low concentrations of nPP. Diets with a broader Ca : nPP ratio improved the digestibility of Ca but were deleterious to the digestibility of P. In this study, apparent digestibility of amino acids was broadly unaffected by dietary Ca and nPP concentrations. However, interactions between Ca and nPP were observed for the digestibility of glutamine, tyrosine and methionine (all P<0.001). Nitrogen digestibility showed discrete optima around 10.0 and 5.0 g/kg nPP and Na digestibility was maximised around 8 to 9.0 g/kg Ca and 4.5 to 5.4 g/kg nPP. These data show that the ratio of Ca : nPP is more influential to mineral digestibility than the absolute dietary concentration of each macro mineral. 相似文献
18.
Gonzalez-Reimers E Rodriguez-Moreno F Martinez-Riera A Mas-Pascual A Delgado-Ureta E Galindo-Martin L Arnay-de la Rosa M Santolaria-Fernandez F 《Biological trace element research》1999,68(1):41-49
To elucidate accumulation of minerals in human iliac arteries with aging, the content of minerals was analyzed by inductively
coupled plasma atomic emission spectrometry. Bilateral common, internal, and external iliac arteries of 16 men and 8 women,
ranging ages from 65 to 93 yr, were examined. It was found that an extremely high accumulation of calcium and phosphorus occurred
in the common iliac artery at old age, being higher than that of the internal and external iliac arteries. It should be noted
that the accumulation of calcium and phosphorus is the highest in the common iliac artery among the human arteries examined
to date.
Regarding sexual differences, the content of calcium and phosphorus in the common and internal iliac arteries was higher in
women than in men, whereas their content in the external iliac artery was lower in women than in men. 相似文献
19.
Minami T Tohno S Utsumi M Moriwake Y Yamada MO Tohno Y 《Biological trace element research》2001,79(1):29-38
The aim of the present study was to determine variability of aluminum (Al) accumulation in human arteries and to observe the
relationship between Al and five other elements (Ca, Fe, Mg, P, and Si) in the arteries. The Al contents in the thoracic aorta,
basilar, coronary, femoral, and radial arteries of 26 human subjects were estimated by an inductively coupled plasma-atomic
emission spectrometer and compared quantitatively to five elements. Al was detected in 88% of the cases in both the femoral
and radial arteries, 73% in the coronary artery, 58% in the aorta, and 31% in the basilar artery. The average Al content was
highest in the femoral artery (48.3 ± 15.0 μg/g dry weight) and lowest in the basilar artery (8.1 ± 3.6 μg/g). The Al had
positive correlations with P, Ca, or Mg in both the aorta and femoral artery, and with Ca or P in the basilar artery. In the
coronary artery, a correlation was found between Al and Si. No relationships were found between Al and each of the five elements
in the radial artery. From these results, Al varied widely among the five arteries and accumulated more in the femoral and
radial arteries but less in the basilar artery. These accumulations of Al were positively correlated with Ca or P in several
arteries, but not sufficiently to explain the accumulation of Al. Further investigations are required to understand the mechanism
of the variability of Al accumulation in the arteries. 相似文献
20.
Tohno S Tohno Y Minami T Moriwake Y Azuma C Ohnishi Y 《Biological trace element research》2002,86(1):23-30
To elucidate the manner of element accumulation in the arteries with aging, the authors investigated the element contents
in the calcified and surrounding sites of the thoracic aortas by inductively coupled plasma-atomic emission spectrometry.
The subjects consisted of three men and five women, ranging in age from 45 to 99 yr. The calcified, calcification-surrounding,
and control (which appeared normal) sites were removed from the thoracic aortas and the element contents were determined.
It was found that the contents of calcium, phosphorus, magnesium, zinc, and aluminum were higher in the calcified site than
in the control site, whereas the contents of sulfur, iron, and lead were lower in the calcified site than in the control site.
The contents of the elements in the surrounding site were intermediate between those of the calcified and control sites, except
for the magnesium and lead contents, which were the lowest.
The mass ratios of magnesium to calcium and phosphorus were lower in the calcified site compared with the surrounding and
control sites, and as calcium and phosphorus increased in the aorta, the mass ratios lowered gradually in the aorta. 相似文献