Symposium on J.-L. Dessalles’s Why we Talk (OUP, 2007): Precis by J.-L. Dessalles,commentaries by E. Machery,F. Cowie,and J. Alexander,Replies by J.-L. Dessalles

This symposium discusses J.-L. Dessalles's account of the evolution of language, which was presented in Why we Talk (OUP 2007).     

Plant collectors in Ecuador: Camp,Prieto, JØrgensen and Giler

The itinerary of W. H. Camp and his assistants in Ecuador has been reconstructed from fieldbooks deposited in the archives of the library at The New York Botanical Garden. The visited localities are listed according to collection numbers, an alphabetical list of the localities with geographical coordinates or best approximation is provided, and a map is presented showing the area where most numbers were collected.     

Genetic,epigenetic, and gene-by-diet interaction effects underlie variation in serum lipids in a LG/J×SM/J murine model

Variation in serum cholesterol, free-fatty acids, and triglycerides is associated with cardiovascular disease (CVD) risk factors. There is great interest in characterizing the underlying genetic architecture of these risk factors, because they vary greatly within and among human populations and between the sexes. We present results of a genome-wide scan for quantitative trait loci (QTL) affecting serum cholesterol, free-fatty acids, and triglycerides in an F₁₆ advanced intercross line of LG/J and SM/J (Wustl:LG,SM-G16). Half of the population was fed a high-fat diet and half was fed a relatively low-fat diet. Context-dependent genetic (additive and dominance) and epigenetic (imprinting) effects were characterized by partitioning animals into sex, diet, and sex-by-diet cohorts. Here we examine genetic, environmental, and genetic-by-environmental interactions of QTL overlapping previously identified loci associated with CVD risk factors, and we add to the serum lipid QTL landscape by identifying new loci.