共查询到20条相似文献,搜索用时 31 毫秒
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Florian MC Dörr K Niebel A Daria D Schrezenmeier H Rojewski M Filippi MD Hasenberg A Gunzer M Scharffetter-Kochanek K Zheng Y Geiger H 《Cell Stem Cell》2012,10(5):520-530
Highlights? Constitutively increasing Cdc42 activity causes aging of young HSCs ? Elevated Cdc42 activity correlates with a loss of cell polarity in aged HSCs ? Inhibition of Cdc42 activity rejuvenates aged LT-HSC function ? Cdc42 inhibition restores the level and spatial distribution of AcH4K16 相似文献
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Highlights? Self-organization is a property of developmental systems and pluripotent stem cells. ? Tissue engineering approaches can be applied to control self-organization in vitro. ? Maturation of pluripotent stem cells in vitro may be promoted by self-organization. ? Subtle, dynamic signals are provided to pluripotent cells through self-organization. 相似文献
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《Current opinion in biotechnology》2013,24(6):1108-1115
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Reconstructing stem cell niches via droplet microfluidic technology.