Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis

1. Download : Download high-res image (170KB)
2. Download : Download full-size image

     

Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension

1. Download : Download high-res image (147KB)
2. Download : Download full-size image

     

Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation

1. Download : Download high-res image (367KB)
2. Download : Download full-size image

     

Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry

1. Download : Download high-res image (205KB)
2. Download : Download full-size image

     

Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

1. Download : Download high-res image (176KB)
2. Download : Download full-size image

     

Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity

1. Download : Download high-res image (245KB)
2. Download : Download full-size image

     

Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations

1. Download : Download high-res image (165KB)
2. Download : Download full-size image

     

TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease

1. Download : Download high-res image (255KB)
2. Download : Download full-size image

     

Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception

1. Download : Download high-res image (312KB)
2. Download : Download full-size image

     

Conformational change of α-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson’s disease

1. Download : Download high-res image (198KB)
2. Download : Download full-size image

     

ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance

1. Download : Download high-res image (163KB)
2. Download : Download full-size image

     

A general chemical principle for creating closure-stabilizing integrin inhibitors

1. Download : Download high-res image (116KB)
2. Download : Download full-size image

     

Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α

1. Download : Download high-res image (156KB)
2. Download : Download full-size image

     

The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages

1. Download : Download high-res image (209KB)
2. Download : Download full-size image

     

The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds

1. Download : Download high-res image (81KB)
2. Download : Download full-size image

     

Activity- and sleep-dependent regulation of tonic inhibition by Shisa7

1. Download : Download high-res image (227KB)
2. Download : Download full-size image

     

Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function

1. Download : Download high-res image (193KB)
2. Download : Download full-size image

     

Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues

1. Download : Download high-res image (231KB)
2. Download : Download full-size image

     

Structure and gating mechanism of the α7 nicotinic acetylcholine receptor

1. Download : Download high-res image (358KB)
2. Download : Download full-size image

     

FOXD3 Regulates VISTA Expression in Melanoma

1. Download : Download high-res image (139KB)
2. Download : Download full-size image