Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion

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Functional interpretation,cataloging, and analysis of 1,341 glucose-6-phosphate dehydrogenase variants

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Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention

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Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes

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3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells

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3D ECM-rich environment sustains the identity of naive human iPSCs

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Widespread,human-associated redondoviruses infect the commensal protozoan Entamoeba gingivalis

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Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids

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Translocation of shorebird siblings shows intraspecific variation in migration routines to arise after fledging

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A plant immune protein enables broad antitumor response by rescuing microRNA deficiency

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Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease

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Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia

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Toward a fine-scale population health monitoring system

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Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy

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3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels

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A route to de novo domestication of wild allotetraploid rice

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Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells

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MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase

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The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes

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A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

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