Time course of the ventilatory response to adjuvant arthritis in the rat

The present study determined the time course of the ventilatory response to adjuvant arthritis in the rat. It was found that the minute ventilation of arthritic rats reliably exceeded that of control animals during a period of about 4 weeks. The ventilatory response had its onset during the 2nd week after inoculation of $\text{Mycobacterium butyricum}$ in the tail base, peaked on day 21, and was statistically reliable up to the 35th day. A smaller difference persisted throughout the further six weeks of the study, which covered 77 days in all. The changes in minute ventilation appeared to be closely time-locked with the changes in body weight and paw diameter which are characteristic of rats with adjuvant arthritis. The peak minute ventilation of individual animals also correlated in a significant manner with changes in weight and in paw diameter. The data are consistent with an earlier attempt to characterize the time course of the chronic pain which is presumably associated with adjuvant arthritis in the rat; minute ventilation is discussed as a possible measure of this putative pain.     

The Use and Nonuse of Companion Animals by Volunteers in Nursing Homes: A Comparative Study

Abstract

This report compares motivation and satisfaction of volunteers who visited residents in nursing homes accompanied by a dog with volunteers who visited the same residents but without a dog. The sample consisted of 40 people, 21 of whom were accompanied by a pet. A questionnaire of 111 items were developed and administered to all participants. Both groups of volunteers had equivalent volunteer experience and their reasons for volunteering were almost identical. No significant differences between the two groups were identified, possibly because of the small size of the sample, but an increased level of staff-volunteer interaction was reported for the pet group.     

Sterilization of Companion Animals: Exploring the Attitudes and Behaviors of Latino Students in South Texas

A sample of 131 Latino students attending a university in south Texas near the United States–Mexico border completed a self-administered questionnaire regarding their companion animals (pets). Compared with dog caregivers (owners) (n = 106), cat caregivers (n = 25) were significantly more likely to favor early spay/neuter of pets and to report that the primary benefit received from their own pet was relational (for example, companionship) rather than functional (for example, sense of safety). The rate of sterilization was significantly higher for cats (60%) than for dogs (26.4%). Sterilization rates were significantly higher for cats whose owners favored early spay/neuter and had accurate knowledge about sterilization of female cats and dogs. Sterilization rates were significantly higher for dogs whose owners had a veterinarian, favored early spay/neuter, and valued relational benefits of guardianship more than functional benefits. Approximately 41% of owners whose pets were not sterilized reported that they wanted puppies or kittens, and 25% reported that the cost of the procedure was the primary barrier. Sterilization programs must include both education about the benefits of sterilization and low-cost spay/neuter services.