共查询到20条相似文献,搜索用时 0 毫秒
1.
R Schwartz 《Federation proceedings》1967,26(3):914-917
2.
3.
4.
5.
6.
G P Wheeler 《Federation proceedings》1967,26(3):885-892
7.
Symposium on immunosuppressive drugs. Biochemistry and pharmacology of purine analogues 总被引:16,自引:0,他引:16
G B Elion 《Federation proceedings》1967,26(3):898-904
8.
9.
10.
11.
Symposium on immunosuppressive drugs. Effect of cancer chemotherapeutic agents on normal tissues in man 总被引:1,自引:0,他引:1
E Frei 《Federation proceedings》1967,26(3):918-924
12.
13.
C R Garcia 《Federation proceedings》1970,29(3):1240-1242
The development of antifertility drugs is reviewed and judged as beneficial to man's social progress, although the need for safer, more convenient, and more effective contraceptives is still recognized. The unreliability and subjectivity of most reports of side effects from pill use is noted, and the need for accurate and comprehensive epidemiological studies of oral contraceptives is emphasized. 相似文献
14.
15.
16.
P Kendall-Taylor 《BMJ (Clinical research ed.)》1984,288(6416):509-511
17.
18.
19.
MariaRosa Costanzo 《Trials》2001,2(1):45-9
Only a few randomized clinical trials have been performed so far in heart transplant recipients, mainly because of the relatively small number of heart transplants performed worldwide each year. The main focus of the few controlled trials that have been completed has been the prevention and treatment of heart allograft rejection. In the area of pharmacologic immunosuppression, both biological agents and drugs have been the subject of investigation. Among the biological agents, chimeric monoclonal antibodies directed against the interleukin (IL)-2 receptor, which have been found to be safe and effective in renal transplant recipients, are now undergoing the test of controlled trials in heart transplant recipients. Immunosuppressive drugs that have been studied in controlled trials include calcineurin inhibitors (such as the microemulsion formulation of cyclosporine and tacrolimus) and inhibitors of purine synthesis, such as mycophenolate mofetil. Non-pharmacologic prophylactic immunosuppression with photopheresis has also been tested in a prospective, multicenter, randomized trial. New immunosuppressive regimens, such as mycophenolate mofetil combined with a monoclonal antibody against the IL-2 receptor, are being tested with the aim to reduce or eliminate calcineurin inhibitors or corticosteroids. Although clinical approaches to the induction of tolerance have undergone preliminary clinical evaluation, the ability to induce tolerance to an allograft in humans remains an elusive goal. 相似文献
20.
Østensen M Khamashta M Lockshin M Parke A Brucato A Carp H Doria A Rai R Meroni P Cetin I Derksen R Branch W Motta M Gordon C Ruiz-Irastorza G Spinillo A Friedman D Cimaz R Czeizel A Piette JC Cervera R Levy RA Clementi M De Carolis S Petri M Shoenfeld Y Faden D Valesini G Tincani A 《Arthritis research & therapy》2006,8(3):209-19
Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed where data were available. Recommendations for drug treatment during pregnancy and lactation are given. 相似文献