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《PLoS biology》2021,19(10)
The widely held assumption that any important scientific information would be available in English underlies the underuse of non-English-language science across disciplines. However, non-English-language science is expected to bring unique and valuable scientific information, especially in disciplines where the evidence is patchy, and for emergent issues where synthesising available evidence is an urgent challenge. Yet such contribution of non-English-language science to scientific communities and the application of science is rarely quantified. Here, we show that non-English-language studies provide crucial evidence for informing global biodiversity conservation. By screening 419,679 peer-reviewed papers in 16 languages, we identified 1,234 non-English-language studies providing evidence on the effectiveness of biodiversity conservation interventions, compared to 4,412 English-language studies identified with the same criteria. Relevant non-English-language studies are being published at an increasing rate in 6 out of the 12 languages where there were a sufficient number of relevant studies. Incorporating non-English-language studies can expand the geographical coverage (i.e., the number of 2° × 2° grid cells with relevant studies) of English-language evidence by 12% to 25%, especially in biodiverse regions, and taxonomic coverage (i.e., the number of species covered by the relevant studies) by 5% to 32%, although they do tend to be based on less robust study designs. Our results show that synthesising non-English-language studies is key to overcoming the widespread lack of local, context-dependent evidence and facilitating evidence-based conservation globally. We urge wider disciplines to rigorously reassess the untapped potential of non-English-language science in informing decisions to address other global challenges.Please see the Supporting information files for Alternative Language Abstracts.A survey of 419,680 peer-reviewed papers in 16 languages reveals that non-English-language studies can expand geographical (by 12-25%) and taxonomic (by 5-32%) coverage of English-language evidence on the effectiveness of biodiversity conservation interventions, especially in biodiverse regions. 相似文献
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Background
In the current era of strong worldwide market couplings the global financial village became highly prone to systemic collapses, events that can rapidly sweep throughout the entire village.Methodology/Principal Findings
We present a new methodology to assess and quantify inter-market relations. The approach is based on the correlations between the market index, the index volatility, the market Index Cohesive Force and the meta-correlations (correlations between the intra-correlations.) We investigated the relations between six important world markets—U.S., U.K., Germany, Japan, China and India—from January 2000 until December 2010. We found that while the developed “western” markets (U.S., U.K., Germany) are highly correlated, the interdependencies between these markets and the developing “eastern” markets (India and China) are volatile and with noticeable maxima at times of global world events. The Japanese market switches “identity”—it switches between periods of high meta-correlations with the “western” markets and periods when it behaves more similarly to the “eastern” markets.Conclusions/Significance
The methodological framework presented here provides a way to quantify the evolvement of interdependencies in the global market, evaluate a world financial network and quantify changes in the world inter market relations. Such changes can be used as precursors to the agitation of the global financial village. Hence, the new approach can help to develop a sensitive “financial seismograph” to detect early signs of global financial crises so they can be treated before they develop into worldwide events. 相似文献5.
Seye Abimbola Sumegha Asthana Cristian Montenegro Renzo R. Guinto Desmond Tanko Jumbam Lance Louskieter Kenneth Munge Kabubei Shehnaz Munshi Kui Muraya Fredros Okumu Senjuti Saha Deepika Saluja Madhukar Pai 《PLoS medicine》2021,18(4)
Seye Abimbola and co-authors argue for a transformation in global health research and practice in the post-COVID-19 world.Summary points
- The Coronavirus Disease 2019 (COVID-19) pandemic, the Black Lives Matter and Women in Global Health movements, and ongoing calls to decolonise global health have all created space for uncomfortable but important conversations that reveal serious asymmetries of power and privilege that permeate all aspects of global health.
- In this article, we, a diverse, gender-balanced group of public (global) health researchers and practitioners (most currently living in the so-called global South), outline what we see as imperatives for change in a post-pandemic world.
- At the individual level (including and especially ourselves), we emphasise the need to emancipate and decolonise our own minds (from the colonial conditionings of our education), straddle and use our privilege responsibly (to empower others and avoid elite capture), and build “Southern” networks (to affirm our ownership of global health).
- At the organisational level, we call for global health organisations to practice real diversity and inclusion (in ways that go beyond the cosmetic), to localise their funding decisions (with people on the ground in the driving seat), and to progressively self-decentralise (and so, divest themselves of financial, epistemic, and political power).
- And at both the individual and organisational level, we emphasise the need to hold ourselves, our governments, and global health organisations accountable to these goals, and especially for governance structures and processes that reflect a commitment to real change.
- By putting a spotlight on coloniality and existing inequalities, the COVID-19 pandemic inspires calls for a more equitable world and for a decolonised and decentralised approach to global health research and practice, one that moves beyond tokenistic box ticking about diversity and inclusion into real and accountable commitments to transformative change.
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Drug discovery in the wake of genomics. 总被引:4,自引:0,他引:4
S Berry 《Trends in biotechnology》2001,19(7):239-240
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Diego A. Moreno Cristina García-Viguera José I. Gil Angel Gil-Izquierdo 《Phytochemistry Reviews》2008,7(2):261-280
Natural pigments from plants are of growing interest as substitutes for synthetic dyes in the food and pharmaceutical industry
and they increase their added value if they possess positive effects on health. These pigments can be added as such if they
are in the legal authorized lists of additives or can be added as phytochemical-enriched plant extract achieving the original
product, which has received it, the new nomenclature of functional food. In this way, we comprise on this review a wide point
of view of a group of natural pigments known as betalains. From a chemical point of view, betalains are ammonium conjugates
of betalamic acid with cyclo-DOPA (betacyanins, violet) and aminoacids or amines (betaxanthins, orange or yellow), which are compounds present in our
diet. Besides and taking into account that one type of betalain, betanin is approved as food colorant (E-162) by the European
Union and that enlarges the specific weight of these compounds in the diet, we have evolved an overview from the biosynthesis,
technology and promoting production, industrial uses as pigments up to physiological and nutritional biovailability or biological
and health-promoting properties of betalains for accessible information to industrials, researchers and consumers. 相似文献
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In view of better linking conservation and sustainable development, it is imperative to optimize the transfer of biodiversity-related knowledge and technology from resource-rich countries to developing countries. All countries signatory to the Convention on Biological Diversity are expected to report on their progress towards achieving the Aichi Biodiversity Targets. However, weak data coverage and the technicality or even unavailability of indicators present major barriers to the monitoring of biodiversity as well as the development of adequate biodiversity policies and management plans in many countries of the global South, hence increasing the North-South knowledge and capacity gap. Capacity development in these countries may hence substantially enrich global biodiversity monitoring and policy. In this effort, ensuring that monitoring programs are realistic and sufficiently embedded in policy remains a challenge. To contribute to the mainstreaming of biodiversity into development cooperation, we developed a capacity development concept that links scientific data to policy development. To guarantee shared ownership, academic institutes and organisations or authorities with responsibilities in biodiversity policy were invited to jointly submit competitive “Monitoring, Reporting and Verification” (MRV) project applications. It appeared that especially ground truthing, economic valuation of biodiversity, and the application of modern technologies in biodiversity monitoring were missing capacities in the global South. Efforts are also required to increase the understanding and use of indicators to avoid them remaining a theoretical concept. As is observed with MRV in the carbon context, increased involvement of local communities is recommended in the global MRV framework, including techniques such as community-based Mapping, Measuring and Monitoring. 相似文献
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Julia ChacnLabella Mickey Boakye Brian J. Enquist William FarfanRios Ragnhild Gya Aud H. Halbritter Sara L. Middleton Jonathan von Oppen Samuel PastorPloskonka Tanya Strydom Vigdis Vandvik Sonya R. Geange 《Ecology and evolution》2021,11(8):3588
The COVID‐19 crisis has forced researchers in Ecology to change the way we work almost overnight. Nonetheless, the pandemic has provided us with several novel components for a new way of conducting science. In this perspective piece, we summarize eight central insights that are helping us, as early career researchers, navigate the uncertainties, fears, and challenges of advancing science during the COVID‐19 pandemic. We highlight how innovative, collaborative, and often Open Science‐driven developments that have arisen from this crisis can form a blueprint for a community reinvention in academia. Our insights include personal approaches to managing our new reality, maintaining capacity to focus and resilience in our projects, and a variety of tools that facilitate remote collaboration. We also highlight how, at a community level, we can take advantage of online communication platforms for gaining accessibility to conferences and meetings, and for maintaining research networks and community engagement while promoting a more diverse and inclusive community. Overall, we are confident that these practices can support a more inclusive and kinder scientific culture for the longer term. 相似文献
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K D Wernecke 《Biometrics》1992,48(2):497-506
A procedure is described for coupling different discriminators to a new (common) decision rule using the corresponding allocation vectors only. This enables one to cope jointly with data of different structure and/or scales of measurement but without strong restrictions on the number of (especially categorical) features. The method is combined with a consequent cross-validation process securing the results reached. Examples from medical diagnostics demonstrate the usefulness of the proposed procedure, especially in comparison with the known linear discriminant analysis as judged from the error rates obtained. 相似文献
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W. E. Seidelman 《BMJ (Clinical research ed.)》1996,313(7070):1463-1467
Fifty years after the Nuremberg medical trial there remain many unanswered questions about the role of the German medical profession during the Third Reich. Other than the question of human experimentation, important ethical challenges arising from medicine in Nazi Germany which have continuing relevance were not addressed at Nuremberg. The underlying moral question is that of the exercise of professional power and its impact on vulnerable people seeking medical care. Sensitisation to the obligations of professional power may be achieved by an annual commemoration and lament to the memory of the victims of medical abuse which would serve as a recurring reminder of the physician''s vulnerability and fallibility. 相似文献
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The role of K+ in the in vivo metabolism of specific phage T4 messengers was studied. By using a mutant of Escherichia coli defective in its ability to accumulate K+ from the growth medium, it was possible to rapidly deplete cells of their intracellular K+ and in this way determine K+-dependent reactions in vivo. The rate constants for accumulation, synthesis, and decay of the early enzymes deoxynucleotide kinase and alpha-glucosyl transferase were determined. It was shown that there is a very close association between mRNA synthesis and its decay, indicating that a mechanism may be present in the cell that can regulate the concentration of these RNAs. Since the mRNA's for these enzymes are very stable in cells depleted of K+, K+ depletion may be a useful method for the isolation of functional T4 mRNA. 相似文献
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