Propagation and amplification of microwave radiation in a plasma channel created in gas by a high-power femtosecond UV laser pulse

The time evolution of a nonequilibrium plasma channel created in a noble gas by a high-power femtosecond KrF laser pulse is investigated. It is shown that such a channel possesses specific electrodynamic properties and can be used as a waveguide for efficient transportation and amplification of microwave pulses. The propagation of microwave radiation in a plasma waveguide is analyzed by self-consistently solving (i) the Boltzmann kinetic equation for the electron energy distribution function at different spatial points and (ii) the wave equation in the parabolic approximation for a microwave pulse transported along the plasma channel.     

Effect of pulse electromagnetic radiation on erythrocyte ghosts

The pulse microwave radiation has been shown to increase the fluorescence intensity of 2-toluidinonaphthanene-6-sulfonate (2,6-TNS) and 1-anilinonaphthalene-8-sulfonate (1,8-ANS) built-in membranes of erythrocyte ghosts. In experiments with 2,6-TNS a frequency dependence of the effect of microwave radiation with maximum within the frequency range of 55-65 Hz has been found. It is suggested that the changes registered with fluorescent probes are induced by mechanical oscillations generated by the pulse microwave radiation.     

The effect of exposure of acetylcholinesterase to 2,450-MHz microwave radiation

The effect of 2,450-MHz pulsed microwave radiation on the enzyme activity of membrane-free acetylcholinesterase was studied while the enzyme was in the microwave field. We found no significant effect of microwave radiation on enzyme activity using a wide variety of power densities, pulse widths, repetition rates, and duty cycles. This suggests that simple, direct modification by microwave energy of acetylcholinesterase structure and enzymic activity is not related to microwave alteration of acetylcholinesterase central nervous system levels.     

A study of the functional activity of macrophages of peritoneal exudate of mice exposed to low-intensity laser radiation in vitro and in vivo

The effect of low-intensity laser radiation generated by semiconductor devices in the red (650 nm) and infrared (850 nm) regions of the spectrum in vitro and in vivo on the phagocytic activity and synthesis of proinflammatory cytokines by peritoneal macrophages during the phagocytosis of bacterial cells has been studied. A culture of the clinical strain of the enteropathogenic bacterium Escherichia coli was used as an object. The radiation dose was varied by changing the power and duration of exposure. The results obtained indicate that infrared low-intensity laser radiation has a stimulating effect on the phagocytic activity of macrophages. It was shown that the effect of low-intensity laser radiation on the activity of the phagocytic process, the enhancement of the adhesion of bacteria by macrophages, killing of bacteria, and the production of proinflammatory cytokines is dose-dependent. The exposure to the rays of the red region of the spectrum on phagocytizing macrophages induced a decrease in their activity; as the dose was increased, the destruction of cells was registered.     

Experimental study of the plasma effect on the generation of microwave radiation in systems with a virtual cathode

Results are presented from experimental studies of the plasma effect on the generation of microwave radiation in systems with a virtual cathode. Using a triode with a virtual cathode as an example, it is shown that the cathode and anode plasmas reduce the generation efficiency; in particular, the power of the generated microwave radiation decreases and the radiation frequency and the microwave pulse duration change appreciably. It is demonstrated that, at high microwave powers, the power radiated into free space can be reduced by the plasma generated at the surface of the output window. This plasma appears due to discharges developing on the window surface under the combined action of bremsstrahlung, UV radiation, electrons and ions arriving from the beam formation zone, and the microwave electric field.     

Thermodynamic response of soft biological tissues to pulsed infrared-laser irradiation.

The physical mechanisms that achieve tissue removal through the delivery of short pulses of high-intensity infrared laser radiation, in a process known as laser ablation, remain obscure. The thermodynamic response of biological tissue to pulsed infrared laser irradiation was investigated by measuring and analyzing the stress transients generated by Q-sw Er:YSGG (lambda = 2.79 microns) and TEA CO2 (lambda = 10.6 microns) laser irradiation of porcine dermis using thin-film piezoelectric transducers. For radiant exposures that do not produce material removal, the stress transients are consistent with thermal expansion of the tissue samples. The temporal structure of the stress transients generated at the threshold radiant exposure for ablation indicates that the onset of material removal is delayed with respect to irradiation. Once material removal is achieved, the magnitude of the peak compressive stress and its variation with radiant exposure are consistent with a model that considers this process as an explosive event occurring after the laser pulse. This mechanism is different from ArF- and KrF-excimer laser ablation where absorption of ultraviolet radiation by the collagenous tissue matrix leads to tissue decomposition during irradiation and results in material removal via rapid surface vaporization. It appears that under the conditions examined in this study, explosive boiling of tissue water is the process that mediates the ablation event. This study provides evidence that the dynamics and mechanism of tissue ablation processes can be altered by targeting tissue water rather than the tissue structural matrix.     

Dipole Mechanism Generation of Terahertz Waves under Laser-Cluster Interaction

The feasibility of dipole radiation of terahertz waves under the action of a femtosecond laser pulse on a cluster is demonstrated theoretically. It is shown that the dipole mechanism of terahertz radiation generation plays a decisive role in the interaction of a laser pulse with small-size clusters with a sufficiently high electron collision frequency. The dependences of the spectral, angular, energetic, and spatiotemporal characteristics of the terahertz signal on the density of free electrons in the cluster plasma under the conditions in which dipole radiation is dominant are investigated. It is shown that the energy of terahertz radiation is maximal under the resonance conditions, when the laser frequency coincides with the eigenfrequency of a spherical cluster.     

电磁辐射对原代培养海马神经元的损伤效应及其机制探讨

研究X带高功率微波、S带高功率微波及电磁脉冲辐射对原代培养海马神经元的损伤效应并探讨其机制。通过体外培养原代海马神经元,建立电磁波辐照细胞模型。采用Annexin V-PI双标记、流式细胞术检测细胞凋亡与坏死,原子力显微镜检测细胞膜表面形态,Fluo-3-AM荧光探针负载、激光扫描共聚焦显微镜测定胞内[Ca2 ]i。结果表明,辐射后海马神经元凋亡与坏死均增加,其中坏死增加明显;细胞膜表面粗糙度加大,膜穿孔增多;胞内[Ca2 ]i明显升高。且以上变化均以X带高功率微波组最重,S带高功率微波组次之,电磁脉冲组最轻。提示细胞膜穿孔增多,膜通透性增加,导致胞外Ca2 内流增加,甚至胞内钙超载是辐射致海马神经元凋亡与坏死的机制之一;三种电磁辐射对海马神经元的损伤程度与照射频率呈正相关。     

Microwave generation by a superluminal source at limiting current densities

It is well known that high-power directed wideband electromagnetic radiation in the microwave range can be generated by a superluminal pulse of the electron emission current. The operation of a simple emitting element driven by a superluminal current pulse and consisting of an accelerating diode with a photocathode and a source of ionizing radiation that initiates electron emission from the cathode is considered. It is shown that the parameters of an elementary superluminal source obey scaling relations that are determined by the growth rate of the electron emission current from the photocathode and the parameters of the accelerating diode. The limiting anode current density and the limiting values of the characteristics of electromagnetic radiation achievable in such a system are determined. The effect of the finite dimensions of the accelerating system on the parameters of the emitter is investigated, and the spatiotemporal characteristics of the generated electromagnetic fields are obtained.     

On the theory of Cherenkov emission from a short laser pulse in a magnetized plasma

Cherenkov emission from a short laser pulse propagating in an underdense plasma along a constant magnetic field is considered. The spectral, angular, energy, and spatiotemporal parameters of the emitted radiation are investigated. It is shown that the spectral content of the radiation and its directionality depend sensitively on the plasma and laser-pulse parameters. For instance, the most intense backward radiation at the upper hybrid frequency is generated by a tightly focused laser pulse.     

XeCl准分子激光辐照对溶菌酶结构的影响

利用荧光光谱、SDS-PAGE和NMR方法,考察308 nm XeCl准分子激光辐照对溶菌酶结构与活性的影响。使用能量密度为0.3 mJ/mm2的激光辐照溶菌酶,脉冲数分别为25、50、100、200、600、1200、1800、3600和7200。结果表明,用低强度激光辐照(低于200个脉冲)时,溶菌酶的活性出现增高趋势。随着激光辐照脉冲数的进一步增大,溶菌酶的活性又开始逐步降低。激光辐照处理后,溶菌酶的荧光强度发生了与生物活性相对应的先增高再降低现象,说明溶菌酶的高级结构发生了显著变化。SDS-PAGE结果显示,经激光辐照后,溶菌酶出现了分子间的聚合。分析溶菌酶的1H-NMR谱发现,辐照后,溶菌酶色氨酸(Trp)111、Trp63和Trp62的化学位移发生了变化,此结果进一步说明,激光辐照使溶菌酶的高级结构发生了变化。该实验可为激光辐照诱导蛋白质去折叠的研究提供参考。     

Generation of terahertz radiation in the reflection of a laser pulse from a dense plasma

The generation of low-frequency (terahertz) electromagnetic radiation in the reflection of a laser pulse from the boundary of a dense plasma is considered. Low-frequency wave electromagnetic fields in vacuum are excited by a vortex electric current that is induced at the plasma boundary by the ponderomotive force of the laser pulse. The spectral, angular, and energy parameters of the low-frequency radiation, as well as the spatiotemporal structure of the emitted waves, are investigated. It is shown that for typical parameters of present-day laser plasma experiments, the power of terahertz radiation can amount to tens of megawatts.     

Effect of low-frequency pulse-modulated 460 MHz electromagnetic irradiation on Drosophila embryos

Effect of electromagnetic radiation 460 MHz with 2.5-40 Hz pulse modulation rate on Drosophila embryos of 15 h 10 m age was studied. It was demonstrated that a 5-min irradiation with 0.12 W/kg average SAR (3 W/kg pulsed SAR) alters the Drosophila percentage of interrupted development. The effect strength depended on the modulation rate with a pronounced decrease at 10 and 16 Hz. A hypothesis about the presence of thermal and non-thermal mechanisms of action of pulse-modulated microwave radiation diversely effecting the embryos has been put forward and grounded.     

Transition radiation generated by a short laser pulse at a plasma-vacuum interface

A theory is presented of the generation of low-frequency transition radiation by a short laser pulse at a plasma-vacuum interface. The wave electromagnetic fields are excited by the vortex electric current that is generated at the plasma boundary by the ponderomotive force of the laser field. The spectral, angular, and energy parameters of the transition radiation, as well as the spatiotemporal structure of the emitted waves in vacuum and in plasma, are investigated. It is shown that the parameters of the transition radiation depend essentially on the ratio of the laser pulse duration to the plasma oscillation period. Under conditions typical of present-day laser-plasma experiments, the transition electromagnetic radiation is generated in the terahertz frequency range and its power can reach several megawatts.     

Nonlinear Thomson scattering of a relativistically strong tightly focused ultrashort laser pulse

The problem of nonlinear Thomson scattering of a relativistically strong linearly polarized ultrashort laser pulse tightly focused into a spot with a diameter of D _F ? λ (where λ is the laser wavelength) is solved. The energy, spectral, and angular distributions of radiation generated due to Thomson scattering from test electrons located in the focal region are found. The characteristics of scattered radiation are studied as functions of the tightness of laser focusing and the initial position of test particles relative to the center of the focal region for a given laser pulse energy. It is demonstrated that the ultratight focusing is not optimal for obtaining the brightest and hardest source of secondary electromagnetic radiation. The hardest and shortest radiation pulse is generated when the beam waist diameter is ?10λ.     

Generation of reactive oxygen species in water under exposure of visible or infrared irradiation at absorption band of molecular oxygen

It is found that in bidistilled water saturated with oxygen hydrogen peroxide and hydroxyl radicals are formed under the influence of visible and infrared radiation in the absorption bands of molecular oxygen. Formation of reactive oxygen species (ROS) occurs under the influence of both solar and artificial light sourses, including the coherent laser irradiation. The oxygen effect, i.e. the impact of dissolved oxygen concentration on production of hydrogen peroxide induced by light, is detected. It is shown that the visible and infrared radiation in the absorption bands of molecular oxygen leads to the formation of 8-oxoguanine in DNA in vitro. Physicochemical mechanisms of ROS formation in water when exposed to visible and infrared light are studied, and the involvement of singlet oxygen and superoxide anion radicals in this process is shown.     

Generation of reactive oxygen species in water under exposure to visible or infrared irradiation at absorption bands of molecular oxygen

It is found that in bidistilled water saturated with oxygen, hydrogen peroxide and hydroxyl radicals are formed under the influence of visible and infrared radiation in the absorption bands of molecular oxygen. Formation of reactive oxygen species (ROS) occurs under the influence of both solar and artificial light sources, including the coherent laser irradiation. The oxygen effect, i.e. the impact of dissolved oxygen concentration on production of hydrogen peroxide induced by light, is detected. It is shown that the visible and infrared radiation in the absorption bands of molecular oxygen leads to the formation of 8-oxoguanine in DNA in vitro. Physicochemical mechanisms of ROS formation in water when exposed to visible and infrared light are studied, and the involvement of singlet oxygen and superoxide anion radicals in this process is shown.     

Effect of microwave radiation on a dusty plasma

The effect of microwave radiation on a complex plasma produced by an external ionizer is studied using numerical simulations. It is shown that, as the radiation intensity increases, the scattering of the incident radiation by charged metal grains is enhanced and radiation at the second harmonic of the incident radiation appears in the scattered spectrum. This effect is associated with the grain charge oscillations caused by the nonlinear action of the microwave field. It is found that, under the action of strong microwave radiation, the grain charge can increase by one order of magnitude. It is shown that, when the microwave intensity is high enough, the distribution of the electric field near a dust grain is shown to change so radically that the field component normal to the grain surface can even change its sign.     

Excitation of magnetic fields by a circularly polarized laser pulse in a plasma channel

The excitation of quasistatic magnetic fields by a circularly polarized laser pulse in a plasma channel is considered. It is shown that, to second order in the amplitude of the electric field of the laser pulse, circular rotation of the plane of polarization of the laser radiation in a radially nonuniform plasma gives rise to a nonlinear azimuthal current and leads to the excitation of the radial and axial components of the magnetic field. The dependence of the magnetic field distribution over the plasma channel on the spatial dimensions of the pulse and on the channel width is investigated for a moderate-power laser pulse. The structure of the magnetic fields excited by a relativistic laser pulse in a wide plasma channel is analyzed.     

Stimulation of Burn Wound Healing in Rats by Nanosecond Repetitive Pulsed Microwave Radiation

Biology Bulletin - The effect of nanosecond repetitive pulsed microwave radiation (RPMR, 10 GHz, 100 ns pulse duration, 8 Hz pulse repetition rate, 140 and 1500 W/cm2 peak power flux density...