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1.
The significance of animals in research cannot be over‐emphasized. The use of animals for research and training in research centres, hospitals and schools is progressively increasing. Advances in biotechnology to improve animal productivity require animal research. Drugs being developed and new interventions or therapies being invented for cure and palliation of all sorts of animal diseases and conditions need to be tested in animals for their safety and efficacy at some stages of their development. Drugs and interventions for human use pass through a similar development process and must be tested pre‐clinically in laboratory animals before clinical trials in humans can be conducted. Therefore, animals are important players in research processes which directly and indirectly benefit animals and humans. However, questions remain as to whether these uses of animals consider the best interests of animals themselves. Various research and training institutions in Tanzania have established some guidelines on animal use, including establishing animal ethics committees. However, most institutions have not established oversight committees. In institutions where there may be guidelines and policies, there are no responsible committees or units to directly oversee if and how these guidelines and policies are enforced; thus, implementation becomes difficult or impossible. This paper endeavours to raise some issues associated with the responsible use of animals in research and training in Tanzania and highlights suggestions for improvement of deficiencies that exist in order to bridge the gap between what ought to be practised and what is practised. 相似文献
2.
Monika Piotrowska 《Bioethics》2021,35(1):98-104
New discoveries are improving the odds of human cells surviving in host animals, prompting regulatory and funding agencies to issue calls for additional layers of ethical oversight for certain types of human–animal chimeras. Of interest are research proposals involving chimeric animals with humanized brains. But what is motivating the demand for additional oversight? I locate two, not obviously compatible, motivations, each of which provides the justificatory basis for paying special attention to different sets of human–animal chimeras. Surprisingly, the sets of animals that actually get flagged for special scrutiny by research and funding guidelines do not correlate with either of the sets of animals that arise when we think about what is motivating additional oversight. What this shows is that existing research policies and funding guidelines are disconnected from their motivation: the rationale for flagging certain types of human–animal chimeras as requiring special oversight is ignored in execution. 相似文献
3.
《Anthrozo?s》2013,26(2):165-184
ABSTRACTThis study describes an online public engagement experiment aimed at investigating how acceptance of animal-based research is affected by: (a) the presence of regulations that govern the use of nonhuman animals in laboratories, (b) the invasiveness of procedures, and (c) the use of genetically modified (GM) animals. To meet these aims, participants were asked if they were willing to accept the use of pigs in different scenarios involving agricultural research. Two-thirds of the 681 participants were female and the majority (58%) were young (19–29 years old) with college or university level education (62%). Participants came from 26 different countries, with the United States, Canada, and the United Kingdom being the top three countries represented. Participants who self-identified as being vegetarians, familiar with animal welfare, animal advocates, environmental advocates, and familiar with animal research were significantly more likely to be opposed to animal-based research. Older participants were significantly less likely to oppose animal-based research. Support significantly decreased when animal-based research involved an invasive procedure or GM animals. Support for invasive research significantly increased when regulation was in place, but regulation had less effect on acceptance of GM animal use. Comments provided by participants illustrated different decision-making strategies regarding different types of animal-based research. Given the increasing use of GM animals in research, more effort is required to understand people's concerns regarding this type of animal use and to determine how these concerns should be reflected in policy. 相似文献
4.
Kovalcsik R Devlin T Loux S Martinek M May J Pickering T Tapp R Wilson S Serota D 《Lab animal》2006,35(9):49-53
Research scientists and IACUC members are faced with the difficult task of balancing the necessity of using animals for experimental research and their mandate to protect the welfare of those animals used in that research. One way to reduce the number of research animals would be to reuse them, but the regulations do not specifically address this topic. To learn more about the reuse of research animals, the authors conducted an online survey of animal facilities involved in preclinical studies. Their results suggest that animal reuse is a common practice in the field. 相似文献
5.
Brown M Carbone L Conlee KM Dawkins MS Duncan IJ Fraser D Griffin G Hampshire VA Lambert LA Mench JA Morton D Richmond J Rollin BE Rowan AN Stephens ML Würbel H;Working Group on Animal Distress in the Laboratory 《Lab animal》2006,35(8):26-30
Finding ways to minimize pain and distress in research animals is a continuing goal in the laboratory animal research field. Pain and distress, however, are not synonymous, and measures that alleviate one may not affect the other. Here, the authors provide a summary of a meeting held in February 2004 that focused on distress in laboratory animals. They discuss the difficulties associated with defining 'distress,' propose methods to aid in recognizing and alleviating distressful conditions, and provide recommendations for animal research conduct and oversight that would minimize distress experienced by laboratory animals. 相似文献
6.
实验动物是现代医学研究中的重要基础和条件,随着我国实验动物科学的迅速发展和实验动物和动物实验质和量的不断提高,对实验动物兽医的需求越来越大,对实验动物兽医的要求和期望也越来越高,本文简要阐述了兽医在动物实验中的作用.文章就实验动物兽医应该具备的资质、实验动物兽医的基本职责以及实验动物健康与兽医管理等方面进行了讨论,明确了实验动物兽医的各项基本职责及任务.兽医在实验动物的管理以及动物实验的过程中有着非常重要的作用,在动物实验中应充分发挥兽医的作用. 相似文献
7.
群体遗传学下动物驯化研究进展 总被引:1,自引:0,他引:1
动物驯化是将野生动物改变为能够长期稳定饲养的家养动物的过程。作为新石器时代农业革命的内容,驯化是人类社会文明进步的重要标志之一。由于和人类的密切关系,驯化不仅改变了动物的野生状态,也改变了人类的生活习性和文明进程。动物驯化研究的关键问题包含驯化祖先是谁、驯化所产生的改变及驯化时间地点等。随着高通量基因组技术和对应分析方法的发展,目前研究动物驯化一般基于群体水平,在群体遗传学的框架下研究动物驯化过程中的重要事件。本文总结了群体遗传学下动物驯化研究的相关内容,包括群体动态历史、选择信号、基因交流等,着重介绍了基因选择初始时间和基因交流时间两个新的拓展内容及分析方法,概述了家猪(Sus scrofa f. domestica)、家鸡(Gallus gallus domesticus)、绵羊(Ovis aries)和山羊(Caprine hircus)等几种主要农业动物近期驯化研究的进展,以期为动物驯化研究提供了新的方向和视角。 相似文献
8.
Underwood WJ 《Lab animal》2005,34(8):29-32
As with other areas of animal research, ensuring the proper training and qualifications of the individuals working with agricultural animals for use in research, teaching, and testing is critical to both animal welfare and the successful outcome of the study or teaching exercise. The author provides guidance for the development of appropriate training programs for organizations that use agricultural animals in research. 相似文献
9.
Andrew Fenton 《Developing world bioethics》2019,19(2):106-115
Though there is a burgeoning interest in applied Buddhist ethics, Buddhist animal research ethics remains an underdeveloped area. In this paper I will explore how some central Buddhist ethical considerations can usefully engage our use of other animals (henceforth, animals) in science. As the scientific use of animals is broad, I will narrow my focus to laboratory science. I will show that, though a Buddhist abolitionism would not be unmotivated, it is possible to reject it. While doing so, it will be important to resist emphasizing elements of Buddhist thought that merely provide reasons to adopt the dominant ethical framework governing laboratory animal research ethics, known as the 3Rs. Though I will suggest how a Buddhist animal research ethics can sometimes permit the use of animals in harmful research, it will also require ethical constraints that resonate with some of the more progressive elements in ‘Western’ bioethics. 相似文献
10.
RNA干扰(RNA interference,RNAi)是由双链RNA介导的,抑制目标基因的表达,沉默靶基因的一种转录后基因沉默机制,并且在真核生物中广泛存在。近年来随着水产养殖业的发展壮大,水产动物疾病频繁爆发,给养殖户带来巨大的经济损失。目前,病毒、寄生虫等病原引起的水产动物疾病的致病机制还有待深入研究。RNA干扰技术的出现为水产动物疾病致病机制的研究提供了强有力的工具。主要对RNA干扰的发现、作用机制以及在水产动物抗病毒和抗寄生虫研究中的应用作以综述,并对未来RNAi技术在水产动物疾病防治中的研究和应用进行了展望,旨为水产动物疾病控制提供参考。 相似文献
11.
Benefiel AC Dong WK Greenough WT 《ILAR journal / National Research Council, Institute of Laboratory Animal Resources》2005,46(2):95-105
Environmental enrichment for laboratory animals has come to be viewed as a potential method for improving animal well-being in addition to its original sense as a paradigm for learning how experience molds the brain. It is suggested that the term housing supplementation better describes the wide range of alterations to laboratory animal housing that has been proposed or investigated. Changes in the environments of animals have important effects on brain structure, physiology, and behavior--including recovery from illness and injury--and on which genes are expressed in various organs. Studies are reviewed that show how the brain and other organs respond to environmental change. These data warrant caution that minor cage supplementation intended for improvement of animal well-being may alter important aspects of an animal's physiology and development in a manner not easily predicted from available research. Thus, various forms of housing supplementation, although utilized or even preferred by the animals, may not enhance laboratory animal well-being and may be detrimental to the research for which the laboratory animals are used. 相似文献
12.
Granstrom DE 《ILAR journal / National Research Council, Institute of Laboratory Animal Resources》2003,44(3):206-210
Challenges and published guidelines associated with appropriate care and use of farm animals in agricultural research conducted outside the laboratory are briefly reviewed. The Animal Welfare Act (Title 9 of the 2000 Code of Federal Regulations), which regulates the care and use of agricultural animals in biomedical research, does not include livestock and poultry used in agricultural research. Farm animal research funded (and thereby regulated) by the US Public Health Service is further discussed in the National Research Council's 1996 Guide for the Care and Use of Laboratory Animals. However, neither of these guidelines adequately addresses the unique attributes of research and teaching designed to improve production agriculture. That information is contained in the Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (the Ag Guide), published by the Federation of Animal Science Societies in 1999. The Ag Guide provides excellent general recommendations for agricultural animal research. It serves as an invaluable resource for institutional animal care and use committees, which attempt to balance the welfare of farm animals and the needs of those working to improve animal agriculture. 相似文献
13.
水产动物的行为研究是渔业领域的重要研究方向,对理解水产动物的行为表型与功能,对提升渔业生产效果有着重要的理论和应用价值。现阶段水产动物行为学的研究成果已被广泛应用于水产动物人工养殖、渔业资源保护和捕捞渔业等多个领域。文章综述了水产动物行为的研究现状,水产动物主要的行为类型,每种行为的发生及其机理,行为间的相互影响及行为在渔业中的应用状况。同时,针对当前水产动物行为学研究存在的问题,提出了今后水产动物行为学的研究方向和研究重点。文章旨在为水产动物行为学领域的研究提供借鉴与启发,并为水产动物行为学研究成果在渔业中的应用提供理论参考。 相似文献
14.
《Anthrozo?s》2013,26(2):133-147
ABSTRACTThe question of how nonhuman animals think is pervasive in the scientific and popular media, yet there is an apparent lack of concordance between findings from research in animal cognition and how this information emerges in popular discourse. The present study investigated the way people conceive of animal thinking, in order to inform the development of an exhibit on animal minds that will address this issue and foster a deeper connection between people and animals. This two-part, sequential study of perceptions of animal thinking used qualitative interviews of visitors to the New York Hall of Science and Staten Island Zoo to develop a quantitative, online consumer survey of American museum visitors. The results show that American museum visitors vary in their perceptions of animal thinking, but appear to be open to new ideas about how animals might think. Participants' responses to the interviews revealed they could easily recognize survival strategies in wild animals, but had reservations about discussions of empathy, deception, and awareness. In addition, animals kept as pets or companion animals in Western culture were commonly perceived to have higher cognitive capacities for thinking than food or other domestic animals. Participants' responses to the online consumer survey appeared to focus on an overall concept of animal thinking, rather than different cognitive dimensions. Although participants were generally neutral in their responses, demographic analysis revealed participants who had dogs and/or cats, a college education, or watched nature shows were more likely to support the belief that animals can think. Participants who had children at home were less likely to support this belief. Further research is needed to determine how different kinds of thought processes are understood by general audiences and how demographic factors might influence perceptions of animal thinking. 相似文献
15.
Hampshire VA 《ILAR journal / National Research Council, Institute of Laboratory Animal Resources》2003,44(3):191-196
Laboratory animal veterinarians sometimes encounter animals with rare conditions and may subsequently become involved in the performance of related animal research outside the laboratory, in homes, in veterinary clinics, or in universities to which owners have donated their animals for study. Similarly, veterinarians may monitor animal companion vaccination studies, performed to optimize preventive health care or minimize physiological variability and research confounders associated with a preventive medicine program for dogs and cats utilized for research procedures. These nontraditional uses of dogs, cats, and other companion animals in research have spurred the establishment of regulations to ensure that the animals benefit from clinical veterinary products and techniques. Included and described are the 2002 Public Health Service Policy, the Animal Welfare Act (AWA), the Federal Food, Drug, and Cosmetic Act, and the regulations of the US Department of Agriculture in response to the AWA. The complexities of clinical research with companion animals outside standard biomedical research facilities are discussed. 相似文献
16.
《Animal behaviour》1988,36(6):1569-1574
The value of using animals in scientific studies of behaviour is discussed in the context of recent controrsies about animal rights and the increasing regulation of research that involves animals. The special contribution that can be made by ethologists is emphasized. 相似文献
17.
While anthropomorphizing nonhuman animals has been shown to increase identification with them and, by extension, concern for their wellbeing, little research has directly tested whether identifying with nonhuman animals is similarly associated with concern for their wellbeing. We tested hypotheses related to this premise across three cross-sectional studies. In study 1 (n = 224), we tested the hypothesis that therians—a group of people who self-identify with nonhuman animals, show greater concern for nonhuman animal rights than non-therian furries—people with a fan-like interest in media featuring anthropomorphized animal characters. In study 2 (n = 206), we further tested this hypothesis using implicit and explicit measures of identification with nonhuman animals to predict behavioral intentions to support nonhuman animal rights. In study 3 (n = 182), we tested the generalizability of our findings in a sample of undergraduate students. Taken together, the studies show that explicit, but not implicit, identification with nonhuman animals predicts greater support for their rights. The implications of these findings for research on anthropomorphism and animal rights activism are discussed, as well as the limitations of these findings and possible avenues for future research. 相似文献
18.
19.
Justin R. Goodman Alka Chandna Casey Borch 《Journal of applied animal welfare science : JAAWS》2013,16(1):82-91
Accreditation of nonhuman animal research facilities by the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) is widely considered the “gold standard” of commitment to the well being of nonhuman animals used in research. AAALAC-accredited facilities receive preferential treatment from funding agencies and are viewed favorably by the general public. Thus, it bears investigating how well these facilities comply with U.S. animal research regulations. In this study, the incidences of noncompliance with the Animal Welfare Act (AWA) at AAALAC-accredited facilities were evaluated and compared to those at nonaccredited institutions during a period of 2 years. The analysis revealed that AAALAC-accredited facilities were frequently cited for AWA noncompliance items (NCIs). Controlling for the number of animals at each facility, AAALAC-accredited sites had significantly more AWA NCIs on average compared with nonaccredited sites. AAALAC-accredited sites also had more NCIs related to improper veterinary care, personnel qualifications, and animal husbandry. These results demonstrate that AAALAC accreditation does not improve compliance with regulations governing the treatment of animals in laboratories. 相似文献
20.
Megan K. Mueller 《Anthrozo?s》2014,27(2):295-308
Existing theory and research suggests that understanding the nuances of particular instantiations of human–animal relationships is important in promoting positive, mutually beneficial relationships between people and animals. One such aspect of human–animal interaction (HAI) involves species of animal involved in the relationship, and how various types of HAI may impact individuals' attitudes about animals. Therefore, the purpose of this study was to explore if species and/or types of animal ownership were associated with feelings of emotional attachment, commitment, and moral orientation toward animals. A sample of young adults (n = 567) from the 4-H Study of Positive Youth Development completed a survey which included questions about animal ownership and attitudes about animals. Regression analyses demonstrated that the species of animal(s) a person owned significantly predicted all three dimensions of attitudes about animals. In addition, latent class analyses identified three prevalent types of animal interaction (no/few animals, small animals only, large and small animals), and multinomial logistic regression within the mixture model indicated that individuals in these subgroups significantly differed in moral orientation scores. Overall, the analyses strengthen support for the notion that species of animal involved in the interaction matters, and that relationships with various species of animals may differ qualitatively. These findings have implications for understanding the role of the relationship between types of animal ownership and attitudes about animals. Exploring the multifaceted nature of human–animal relationships is important in understanding how to optimize the person and animal characteristics that are associated with adaptive, mutually beneficial human–animal relationships. 相似文献