共查询到20条相似文献,搜索用时 155 毫秒
1.
2.
Concanavalin A, added to freshly isolated rabbit thymocytes, markedly enhanced the extracellular appearance of non-immunoglobulin proteins. Time course studies revealed that the onset of enhancement occurred virtually without delay. The effect appeared to be restricted only to certain of the thymus-derived cells because thymocytes obtained from rabbits treated with hydrocortisone, as well as splenocytes derived from untreated rabbits essentially did not exhibit the enhancement. Stimulation by concanavalin A was specific in that pokeweed mitogen and lipopolysaccharide were without effect and also in that α-methyl-mannoside, but not galactose, abrogated the concanavalin A-mediated enhancement. Experiments with mouse thymocytes demonstrated that the cells which responded to concanavalin A were primarily cells that bear the θ-antigen on their surface (T-cells). 相似文献
3.
4.
5.
《微生物学免疫学进展》1994,(2)
福氏2a痢疾菌LPS经两种方法解毒后与破类制成结合物的比较本文报道了将痢疾杆菌福氏2a型LPS经两种方法解毒后与破伤风类毒素制备成结合物的理化和免疫学性质。将痢疾杆菌福氏2a型的LPS通过醋酸水解(切断KDO和类脂A之间的键)和酰肼水解(切断类脂A上... 相似文献
6.
Effect of Concanavalin A on Phagocytosis 总被引:11,自引:0,他引:11
RICHARD D. BERLIN 《Nature: New biology》1972,235(54):44-45
Concanavalin A has been shown to inhibit phagocytosis by polymorphonuclear leucocytes. The effect is reversed by specific sugars. 相似文献
7.
嗜热放线菌是引起农民肺的主要病因,但其致病菌株可有多种。我们应用SDS-PAGE技术对引起农民肺的三株嗜热放线菌的电泳图谱进行了对比分析,发现这三种嗜热放线菌多肽的电泳图谱各不相同,都具有特征性的主要带型。实验结果表明SDS-PACE技术有助于快速鉴定嗜热放线菌菌种。 相似文献
8.
《微生物学免疫学进展》1994,(2)
口服IgA聚合体预防霍乱弧菌在新生小鼠体内的定居作者分离纯化了对霍乱弧菌LPS特异的单克隆IgA并得到其单体和聚合体,采用新生小鼠为动物模型研究了IgA的被动保护效果,实验证明:对新生小鼠口服攻毒前1小时口服抗霍乱弧菌LPS的IgA聚合体,能降低弧菌... 相似文献
9.
10.
12.
《微生物学免疫学进展》1994,(2)
重组BCG口服免疫诱导的细胞和体液免疫应答最近研究证明,外源基因能在牛分枝杆菌BCG中表达,用这些重组分枝杆菌免疫小鼠可诱导抗外来蛋白的细胞和抗体免疫应答。近年来的许多研究也证实了肠道和呼吸道粘膜淋巴系统在防御感染方面的贡献,因此,迫切需要能够刺激粘... 相似文献
13.
14.
嗜铬颗粒蛋白A(Chromogranin A,CGA)属于独特的酸性可溶性蛋白质家族,遍布于动物内分泌系统、神经系统和免疫系统,与其他激素和多肽共贮存、共分泌.在CGA上有许多碱性氨基酸对,成为潜在的激素原转化酶切割位点.很多切割产物已经被鉴定,其中有些具有生物学功能.近年的研究表明,在多种病理、生理状态下,CGA及其衍生片段在组织中含量升高,发挥抑制性生理功能或作为疾病诊断指标.嗜铬颗粒蛋白A的N端衍生片段在机体防御系统中的抗菌功能、在心血管系统中的抗血管收缩功能已被阐明,使其作为临床候选药物具有巨大潜力;CGA完整片段在内分泌肿瘤和神经内分泌肿瘤中含量升高,可作为内分泌肿瘤和神经内分泌肿瘤诊断指标,但其在肿瘤发生过程中的作用还未见报道. 相似文献
15.
16.
17.
18.
N. Rashevsky 《Bulletin of mathematical biology》1958,20(3):275-280
In a recent paper (Bull. Math. Biophysics, 20, 245, 1958), Robert Rosen applied topological considerations to the study of an organism as a whole. Those considerations
have no direct relation to the principle of biotopological mapping. They rather represent a topological model of an organism,
especially a model of the repair mechanisms which organisms possess for lost or impaired parts. In this note it is shown that
the model introduced by Rosen may possibly be derived from the principle of biotopological mapping plus a proper definition
of the primordial. Such a derivation may also provide a clue to a proper biotopological approach to the problem of multiplication
of organisms. 相似文献
19.
20.
《微生物学免疫学进展》1994,(2)
Hib在调理过程中补体成分C_3的外膜蛋白结合位点用从正常人血清(NHS)分离出的不同浓度的IgG抗体调理I(125)标记的b型流感嗜血杆菌(Hib)菌体,分离纯化出IgG-外膜蛋白(OMP)复合物。用SDS-PAGE和放射免疫沉淀试验进行分析,结果... 相似文献