共查询到20条相似文献,搜索用时 687 毫秒
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升麻为毛茛科升麻属植物,在我国分布广泛、品种繁多,其药用历史已有两千余年。升麻化学成分复杂,其特征活性成分为Cycloartane型三萜。现代药理研究表明,升麻具有缓解围绝经期综合征、抗肿瘤、抗炎、抗病毒等作用,不同品种的升麻药材存在品质差异。对升麻化学成分、药理活性及药材品质进行文献归纳,分析升麻开发研究中存在的问题,旨在为升麻资源的深度开发提供参考。 相似文献
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芹菜化学成分及药理活性研究进展 总被引:24,自引:0,他引:24
介绍了芹菜的化学成分及药理活性研究概况。芹菜主要含有挥发油、脂肪酸和黄酮类等化学成分,具有抗菌杀虫、抗氧化、抗肿瘤及抗心血管疾病等药理活性。作为药食两用且广泛种植的植物,对其进行进一步的研究和开发具有重要的意义。 相似文献
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对鸢尾属植物及近缘植物射干种子中化学成分的研究情况,以及相关的一些药理研究进行了综述,这些植物的种子所含化学成分以醌类、酚类等为主,其中一些具有显著药理活性,为其开发利用提供参考。 相似文献
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为更好的开发利用鱼藤属植物的药理活性,本文对其化学成分研究进行了综述.经调研文献,鱼藤属植物的化学成分主要包括黄酮、异黄酮、鱼藤酮等;药理活性主要表现在抗氧化、抗菌、杀虫等方面. 相似文献
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半枝莲中印黄芩甙的R-HPLC分析代雪平魏波(河南省药检所,郑州450003)(河南省人民医院药剂科,郑州450003)R┐HPLCanalysisofscutelarinfromScutelariabarbataD.DonDaiXue-Ping(H... 相似文献
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Anticancer activity and mechanism of Scutellaria barbata extract on human lung cancer cell line A549 总被引:14,自引:0,他引:14
Scutellaria barbata (S. barbata), a traditional Chinese herbal medicine native to southern China, is widely used as an anti-inflammatory and a diuretic in China. Several studies have indicated that extracts of S. barbata have growth inhibitory effects on a number of human cancers. Treatment of lung cancer, digestive system cancers, hepatoma, breast cancer, and chorioepithelioma by S. barbata extracts was reported. However, the mechanism underlying the antitumor activity was unclear. In this study, we studied the growth inhibitory effect of S. barbata and determined its mechanism of antitumor activity using human lung cancer cell line A549. Our results showed that ethanol extracts of S. barbata greatly inhibited A549 cell growth, with IC50 of 0.21 mg/ml. The major mechanisms of inhibition included cell apoptosis and cytotoxic effects. cDNA microarray analysis showed that 16 genes, involved in DNA damage, cell cycle control, nucleic acid binding and protein phosphorylation, underwent more than 5-fold change. These data indicated that these processes are involved in S. barbata-mediated killing of cancer cells. A surprising finding is that CD209, related to dendritic cell (DC) function, was dramatically downregulated by 102-fold. Further functional studies are needed to assess the role of the array-identified genes in S. barbata mediated anticancer activity. 相似文献
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FRANCISCO M. VÁZQUEZ JUAN A. DEVESA 《Botanical journal of the Linnean Society. Linnean Society of London》1997,124(2):201-209
Two new species of Stipa L. S. meridionalis and S. magrebensis, are described from northern Africa, and two new combinations have been made: V. barbata subsp. breripila and S. gigantea subsp. maroccana. 相似文献
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半枝莲中二萜内酯和黄酮化合物的分离和鉴定 总被引:1,自引:0,他引:1
半枝莲(Scutellaria barbata D.Don)为唇形科黄芩属植物,全草入药,具有清热解毒,化瘀利尿,消肿止痛和抗癌等功效。国内学者报道从全草中分得红花素(carthamidin)、异红花素(isocarthamidin)、印黄芩甙(scutellarein)、β-谷甾醇(β-sitosterol)、硬脂酸(stearic acid)和生物碱。台湾学者从中分离得汉黄芩素(wogonin)、5-羟基-7,8-二甲氧基黄酮(5-hydroxy-7,8-dimethoxyflavone)、半枝莲素(Rivularin)。我们从全草的乙醇提取液中分得两个化合物,经鉴定为汉黄芩素、新穿心莲内酯,该内酯在本植物中属首次发现。 相似文献
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By filter saturation hybridizations the ribosomal (r)DNA contents of the ovaries Calliphora erythrocephala, Drosophila hydei, and Sarcophaga barbata have been measured in comparison to the rDNA percentages of their diploid brains. The measurements of the ovarian rDNA have been carried out on ovaries where the nurse cells in the distal egg chamber of the ovarioles had reached their highest ploidy level. The diploid rDNA content of each of the respective species was chosen as a 100% standard and the rDNA amounts of the ovaries were related to this 100% level. The results show that the ovaries of C. erythrocephala contain 135% rDNA whereas the rDNA contents in the ovaries of D. hydei and S. barbata are only 51% and 47%, respectively. Measurements carried out on isolated nuclei of the nurse cells and follicle cells in D. hydei show that both have a reduced rDNA content in comparison to the brains (45% and 70%, respectively). The data are discussed in relation to the problem of an rDNA amplification in the germ cells and an rDNA underreplication in polyploid nuclei. 相似文献
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Gentianopsis paludosa (Hook. f.) Ma (Gentianaceae) is an important species in Tibetan folk medicine commonly used to clear away the "heat evils" and toxic materials. A survey of market samples revealed that nine adulterant species, Gentianopsis barbata, G. contorta, G. grandis, Halenia elliptica, Lomatogonium macranthum, L.rotatum, Swertia angustifolia, S. bifolia and S. erythrosticta, are often marketed as G. paludosa. Methods to distinguish G. paludosa from its adulterants are limited by current morphological and chemical methods. DNA sequence analysis of the nuclear ribosomal DNA internal transcribed spacer region (ITS) was used in the differentiation of G.paludosa from the adulterant species. The data showed that the internal transcribed spacer regions differ significantly between G. paludosa and all nine adulterant species, so that they could be easily distinguished at the DNA level. 相似文献
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云南省是中国乃至世界兰科(Orchidaceae)植物最为丰富的地区之一,近年来随着调查研究工作的深入,发现了不少新属、新种、新记录属以及新记录种[1-10]。笔者近年来对云南南部和东南部植物区系进行调查,并通过标本鉴定和相关资料查阅,发现了4个云南新记录属和9个云南新记录种。其中, 相似文献