KEY WORD INDEX TO VOLUME 12, 2002

Mdo]ase A.................AaIT……...........….accines.....,..............actin .....................actin—binding protein.....AFLP….…..............alpha—fetoprotein.........ascular smooth muscle cellsastacin.......。..ATF/CREB......auxin effiux carrierB and C mRNAsB chromosome.Brassica junceaBrassica juncea 85143104207207 63151123163177247 85 63235247cancer..........................]l cardioascular diseases...............105cDNA clone……….……..199cell cycle…............…….…     

Genetics of osteoarticular disorders,Florence, Italy, 22–23 February 2002

Osteoporosis (OP) and osteoarthritis (OA), the two most common age-related chronic disorders of articular joints and skeleton, represent a major public health problem in most developed countries. They are influenced by environmental factors and exhibit a strong genetic component. Large population studies clearly show their inverse relationship; therefore, an accurate analysis of the genetic bases of one of these two diseases may provide data of interest for the other disorder. The discovery of risk and protective genes for OP and OA promises to revolutionize strategies for diagnosing and treating these disorders. The primary goal of this symposium was to bring together scientists and clinicians working on OP and OA in order to identify the most promising and collaborative approaches for the coming decade. This meeting put into focus the importance of an adequate genetic approach to several areas of research: the search for the genetic determinants underlying new susceptibilities, the optimization of previously acquired data; the establishment of correlations between genetic polymorphism and functional variants, and gene–gene and gene–environment interactions (particularly those between genes and nutrients). An adequate genetic approach is also essential with regard to determining more selective criteria for phenotypic definition of familial OP, in order to obtain more homogeneous and statistically powerful family-based studies. The symposium concluded with an interesting overview of the future perspectives offered by DNA microarray technologies for identifying novel candidate genes, for developing proteomics and bioinformatics analyses and for designing low-cost clinical trials.     

微生物学通报2002年,第29卷总目录

第　 1　期研究报告直链烷基苯磺酸钠 (ＬＡＳ)降解菌的筛选及其降解特性的初步研究应启锋 ,肖昌松 ,纪树兰 ( 1)………………脂肪酶高产菌株选育和菌种库的建立宋　欣 ,魏留梅 ,刘瑞田 ,曲音波 ( 6)………………………………………利用重组大肠杆菌产聚 4 羟基丁酸的研究宋水山 ( 10 )…………………………………………………………………高产虾青素的红发夫酵母菌种的选育王　普 ,裘娟萍 ,郑裕国 ,沈寅初 ( 15)………………………………………植物油和脂肪酸对灰树花深层发酵的作用雷德柱 ,高大维 ,于淑娟 ( 19)…………………………………     

A Brief Report on the Seventh International Workshop on Seed Biology, Salamanca, Spain, May 2002

TheSeventhInternationalWorkshoponSeedBiolo gywasheldfrom 1 2to 1 6May ,2 0 0 2inUniversityofSalamanca ,Spain .ThiswasthefirstworkshoptobeheldentirelyundertheInternationalSocietyforSeedScience(ISSS)banner.About 30 0seedscientistsfrom 2 0coun triesattendedthisworkshop .Aftertheopeningceremony ,thepresident_elect,Prof.DerekBewley ,fromGuelphUniversityofCanada ,openedwithastimulatingoverviewofseedsinscienceandsociety ,whichwasentitled“SeedsofHope,SeedsofDespair” .Hereviewedthehis tory…     

Occurrence,distribution and transport of pesticides into the Salton Sea Basin,California, 2001–2002

The Salton Sea is a hypersaline lake located in southeastern California. Concerns over the ecological impacts of sediment quality and potential human exposure to dust emissions from exposed lakebed sediments resulting from anticipated shrinking of shoreline led to a study of pesticide distribution and transport within the Salton Sea Basin, California, in 2001–2002. Three sampling stations—upriver, river mouth, and offshore—were established along each of the three major rivers that discharge into the Salton Sea. Large-volume water samples were collected for analysis of pesticides in water and suspended sediments at the nine sampling stations. Samples of the bottom sediment were also collected at each site for pesticide analysis. Sampling occurred in October 2001, March–April 2002, and October 2002, coinciding with the regional fall and spring peaks in pesticide use in the heavily agricultural watershed. Fourteen current-use pesticides were detected in water and the majority of dissolved concentrations ranged from the limits of detection to 151 ng/l. Diazinon, EPTC and malathion were detected at much higher concentrations (940–3,830 ng/l) at the New and Alamo River upriver and near-shore stations. Concentrations of carbaryl, dacthal, diazinon, and EPTC were higher in the two fall sampling periods, whereas concentrations of atrazine, carbofuran, and trifluralin were higher during the spring, which matched seasonal use patterns of these pesticides. Current-use pesticides were also detected on suspended and bed sediments in concentrations ranging from detection limits to 106 ng/g. Chlorpyrifos, dacthal, EPTC, trifluralin, and DDE were the most frequently detected pesticides on sediments from all three rivers. The number of detections and concentrations of suspended sediment-associated pesticides were often similar for the river upriver and near-shore sites, consistent with downstream transport of pesticides via suspended sediment. While detectable suspended sediment pesticide concentrations were more sporadic than detected aqueous concentrations, seasonal trends were similar to those for dissolved concentrations. Generally, the pesticides detected on suspended sediments were the same as those on the bed sediments, and concentrations were similar, especially at the Alamo River upriver site. With a few exceptions, pesticides were not detected in suspended or bed sediments from the off-shore sites. The partitioning of pesticides between water and sediment was not predictable from solely the physical–chemical properties of individual pesticide compounds, but appear to be a complicated function of the quantity of pesticide applied in the watershed, residence time of sediments in the water, and compound solubility and hydrophobicity. Sediment concentrations of most pesticides were found to be 100–1,000 times lower than the low-effects levels determined in human health risk assessment studies. However, maximum concentrations of chlorpyrifos on suspended sediments were approximately half the low-effects level, suggesting the need for further sediment characterization of lake sediments proximate to riverine inputs. Guest editor: S. H. Hurlbert The Salton Sea Centennial Symposium. Proceedings of a Symposium Celebrating a Century of Symbiosis Among Agriculture, Wildlife and People, 1905–2005, held in San Diego, California, USA, March 2005     

Spatiotemporal Patterns of Japanese Encephalitis in China, 2002–2010

Objective

The aim of the study is to examine the spatiotemporal pattern of Japanese Encephalitis (JE) in mainland China during 2002–2010. Specific objectives of the study were to quantify the temporal variation in incidence of JE cases, to determine if clustering of JE cases exists, to detect high risk spatiotemporal clusters of JE cases and to provide evidence-based preventive suggestions to relevant stakeholders.

Methods

Monthly JE cases at the county level in mainland China during 2002–2010 were obtained from the China Information System for Diseases Control and Prevention (CISDCP). For the purpose of the analysis, JE case counts for nine years were aggregated into four temporal periods (2002; 2003–2005; 2006; and 2007–2010). Local Indicators of Spatial Association and spatial scan statistics were performed to detect and evaluate local high risk space-time clusters.

Results

JE incidence showed a decreasing trend from 2002 to 2005 but peaked in 2006, then fluctuated over the study period. Spatial cluster analysis detected high value clusters, mainly located in Southwestern China. Similarly, we identified a primary spatiotemporal cluster of JE in Southwestern China between July and August, with the geographical range of JE transmission increasing over the past years.

Conclusion

JE in China is geographically clustered and its spatial extent dynamically changed during the last nine years in mainland China. This indicates that risk factors for JE infection are likely to be spatially heterogeneous. The results may assist national and local health authorities in the development/refinement of a better preventive strategy and increase the effectiveness of public health interventions against JE transmission.     

22nd European Workshop for Rheumatology Research, Leiden, The Netherlands, 28 February–3 March 2002

The European Workshop for Rheumatology Research met this year in Leiden, The Netherlands. The Workshop provided a platform to feast on new technologies and how they have taken research programmes forward. While there will be the inevitable delay during which mechanisms are devised for analysing the huge amount of information generated by these technologies, there is a lot already to look forward to. Highlights included genomic, reverse genomic and proteomic approaches to understanding disease pathogenesis and to identifying new therapeutic targets. Opportunities for exploring whether pharmacogenomics has a place in the clinic are now a reality, and phage display technology has been applied to in vivo arthritis models to identify human synovial microvascular 'post codes'.     

Reconstruction of coral reef fisheries catches in American Samoa, 1950–2002

Fisheries catches from Pacific Island coral reefs are rarely recorded in official statistics. Reconstruction of catch estimates with limited hard data requires interpolation and assumptions, justifiable only by the unsatisfactory alternative of continued substitution of zero catches, a common policy interpretation for ‘no data’. Uncertainties associated with reconstructions are high, requiring conservative estimation. American Samoan domestic fisheries consist of an artisanal, small-boat sector, whose commercial catches are reported, and a shore-based subsistence sector, with no regular reporting. Our catch reconstruction (with large pelagic species removed) suggested a 79% decrease in catches between 1950 (752 t) and 2002 (155 t). Accounting for rapid human population growth on the main island, the per capita catch rate may have declined from 36.3 kg·person⁻¹ year⁻¹ in 1950 to 1.3 kg·person⁻¹ year⁻¹ by 2002, while the catch rate for the inhabited outer islands has been independently reported as 58.6 kg·person⁻¹ year⁻¹. Catch per area of coral reef (to 50-m depth) may have declined from 5.5 to 0.7 t km⁻² year⁻¹ for the main island, and from 9.1 to 4.9 t km⁻² year⁻¹ for the outer islands, for 1950 and 2002, respectively. Summed for 1950–2002, our reconstruction suggested a 17-fold difference between reconstructed estimates and reported statistics.     

Wild boar hunting and socioeconomic trends in Northern Greece, 1993–2002

Wild boar (Sus scrofa) populations increased worldwide in the last decade, but boar hunters have decreased. To maintain and increase hunters and to clarify the problems for sustainable hunting, we investigated their activities, attitudes, and socioeconomic trends. Drama and Kavala, Northern Greece have the best wild boar habitat in the country. We estimated the percentage of hunters hunting wild boar in Drama and Kavala and studied their profile to determine how the recent socioeconomic changes in the region affected numbers, activities, attitudes, and socioeconomic trend, from 1993 to 2002. In 1993, data were gathered through a questionnaire distributed randomly to 411 and 480 hunters in Drama and Kavala, respectively. In 2002, 320 and 400 questionnaires were collected in Drama and Kavala, respectively. In Drama, 13.6% of the hunters hunted wild boar in 1993 and 12.3% in 2002. In Kavala, 10.0% hunted wild boar in 1993 and 9.3% in 2002. The average age of hunters in Drama in 1993 was 37.9 years and 39.4 in 2002. In Kavala, the average age per hunter was reduced from 42.3 to 37.4 years. The average hunting experience had increased by 4.8% and 0.6%, respectively. In 2002, there was an increase in the distance traveled for hunting, the level of education of the hunters, the number of people working in the private sector, and in the public service. Wild boar hunters are mainly married, middle income class, earning 4,000–7,500 Euros/year. The above data will allow managers to better understand the socioeconomics of the hunters of wild boar and may be able to use the data to encourage increased hunting.     

Effect of Reduced Winter Precipitation and Increased Temperature on Watershed Solute Flux, 1988–2002, Northern Michigan

Since 1987 we have studied weekly change in winter (December–April) precipitation, snowpack, snowmelt, soil water, and stream water solute flux in a small (176-ha) Northern Michigan watershed vegetated by 65–85 year-old northern hardwoods. Our primary study objective was to quantify the effect of change in winter temperature and precipitation on watershed hydrology and solute flux. During the study winter runoff was correlated with precipitation, and forest soils beneath the snowpack remained unfrozen. Winter air temperature and soil temperature beneath the snowpack increased while precipitation and snowmelt declined. Atmospheric inputs declined for H⁺, NO₃⁻, NH₄⁺, dissolved inorganic nitrogen (DIN), and SO₄²⁻. Replicated plot-level results, which could not be directly extrapolated to the watershed scale, showed 90% of atmospheric DIN input was retained in surface shallow (<15 cm deep) soils while SO₄²⁻ flux increased 70% and dissolved organic carbon (DOC) 30-fold. Most stream water base cation (C_B), HCO₃⁻, and Cl⁻ concentrations declined with increased stream water discharge, K⁺, NO₃⁻, and SO₄²⁻ remained unchanged, and DOC and dissolved organic nitrogen (DON) increased. Winter stream water solute outputs declined or were unchanged with time except for NO₃⁻ and DOC which increased. DOC and DIN outputs were correlated with the percentage of winter runoff and stream discharge that occurred when subsurface flow at the plot-level was shallow (<25 cm beneath Oi). Study results suggest that the percentage of annual runoff occurring as shallow lateral subsurface flow may be a major factor regulating solute outputs and concentrations in snowmelt-dominated ecosystems.