Primary mechanisms of the biological effect of electromagnetic fields

Based on the model of a bulk knitted structure, a possible mechanism of action of an external electromagnetic field on biological systems was proposed. The electromagnetic field affects biological processes through changes in the rates of biochemical reactions in response to changes in the conformational properties of water in the electromagnetic field.     

Excitation of waves in an inhomogeneous plasma

The evolution of initial perturbations in a spatially inhomogeneous cold electron plasma in the absence of an external magnetic field is considered. The excitation of both continuous-spectrum bulk plasma waves and surface plasma waves with a discrete frequency spectrum is investigated. Analytic solutions are obtained in the long-wavelength limit, and the excitation of waves of arbitrary length is analyzed numerically. The local, integral, and spatial spectra are calculated, as well as the field structures and dispersion properties of waves in waveguides filled nonuniformly with a plasma. It is shown that, in a plasma with a smooth boundary, there also exist surface waves with a discrete spectrum (although with somewhat different properties as compared to those in a plasma with a sharp boundary), which are excited together with continuous-spectrum bulk waves during the evolution of the initial perturbation.     

Coupled transverse modes of coaxial metal waveguides completely filled with magnetoactive current-carrying plasma

The propagation of ordinary bulk modes coupled with extraordinary surface modes in coaxial metal waveguides completely filled with cold magnetoactive plasma is investigated theoretically. The interaction between modes propagating across the waveguide axis in the presence of the axial and azimuthal components of the external magnetic field is examined. The effect of the azimuthal magnetic field on the dispersion properties of these modes is thoroughly studied for the case of a uniform plasma.     

Modeling of antibiotics production in magneto three-phase airlift fermenter

A mathematical model is developed to describe the performance of a three-phase airlift reactor utilizing a transverse magnetic field. The model is based on the complete mixing model for the bulk of liquid phase and on the Michaelis-Menten kinetics. The model equations are solved by the explicit finite difference method from transient to steady state conditions. The results of the numerical simulation indicate that the magnetic field increases the degree of bioconversion. The mathematical model is experimentally verified in a three-phase airlift reactor with P. chrysogenum immobilized on magnetic beads. The experimental results are well described by the developed model when the reactor operates in the stabilized regime. At relatively high magnetic field intensities a certain discrepancy in the model solution was observed when the model over estimates the product concentration.     

Electrostatic electron vortex structure in a plasma in an external magnetic field

A previously developed method for describing vortex structures is used to construct electrostatic vortices in a plasma in an external magnetic field. An equation for the radial electric field that gives rise to azimuthal electron drift in crossed electric (E _r ) and magnetic (B _z ) fields is derived without allowance for the magnetic field of the electron currents. Two types of the resulting electrostatic vortex structures with a positive and a negative electric potential at the axis are analyzed. The results obtained are compared with experimental data on vortex structures.     

Effects of an external magnetic field on the flock size and sedimentation of activated sludge

Effects of an external magnetic field on sedimentation enhancement were investigated using three kinds of practical activated sludge. An indoor experiment was setup (3.5l aeration vessel) equipped with a broth circulation system and 800 G of external magnetic field. The application of an external magnetic field to the activated sludge enhanced the sedimentation irrespective of the nature of the activated sludge. At the same time, the flock size of the sludge was enlarged by the external magnetic field. However, the surface zeta potentials of the sludge were not changed by the external magnetic field. Addition of FeCl₃ to the sludge enhanced the effects of the external magnetic field. Based on these results, the following mechanism for the enhancement of sedimentation by the external magnetic field is suggested: activated sludge containing iron was magnetized during entry to the magnetic field and coagulated with the magnetic force. As a consequence, the flock size was enlarged. Almost the same sedimentation enhancement by external magnetization was confirmed by a pilot scale magnetization system (2.0 m³ of aeration vessel) when the airlift type of mild broth circulation system was equipped with a 5000 G magnetic field.     

Solitary fast magnetosonic waves propagating obliquely to the magnetic field in cold collisionless plasma

Solutions describing solitary fast magnetosonic (FMS) waves (FMS solitons) in cold magnetized plasma are obtained by numerically solving two-fluid hydrodynamic equations. The parameter domain within which steady-state solitary waves can propagate is determined. It is established that the Mach number for rarefaction FMS solitons is always less than unity. The restriction on the propagation velocity leads to the limitation on the amplitudes of the magnetic field components of rarefaction solitons. It is shown that, as the soliton propagates in plasma, the transverse component of its magnetic field rotates and makes a complete turn around the axis along which the soliton propagates.     

Antibiotics production in a fluidized bed reactor utilizing a transverse magnetic field

A mathematical model is developed to describe the performance of a three-phase fluidized bed reactor utilizing a transverse magnetic field. The model is based on the axially dispersed plug flow model for the bulk of liquid phase and on the Michaelis-Menten kinetics. The model equations are solved by the explicit finite difference method from transient to steady state conditions. The results of the numerical simulation indicate that the magnetic field increases the degree of bioconversion. The mathematical model is experimentally verified in a three-phase fluidized bed reactor with Penicillium chrysogenum immobilized on magnetic beads. The experimental results are well described by the developed model when the reactor operates in the stabilized regime. At low and relatively high magnetic field intensities certain discrepancy in the model solution is observed when the model over estimates the product concentration.     

Nonlinear dynamics and chaotization of oscillations of a virtual cathode in an annular electron beam in a uniform external magnetic field

Results are presented from a numerical study of the effect of an external magnetic field on the conditions and mechanisms for the formation of a virtual cathode in a relativistic electron beam. Characteristic features of the nonlinear dynamics of an electron beam with a virtual cathode are considered when the external magnetic field is varied. Various mechanisms are investigated by which the virtual cathode oscillations become chaotic and their spectrum becomes a multifrequency spectrum, thereby complicating the dynamics of the vircator system. A general mechanism for chaotization of the oscillations of a virtual cathode in a vircator system is revealed: the electron structures that form in an electron beam interact by means of a common space charge field to give rise to additional internal feedback. That the oscillations of a virtual cathode change from the chaotic to the periodic regime is due to the suppression of the mechanism for forming secondary electron structures.     

Investigation of the chaotic dynamics of an electron beam with a virtual cathode in an external magnetic field

The effect of the strength of the focusing magnetic field on chaotic dynamic processes occurring in an electron beam with a virtual cathode, as well as on the processes whereby the structures form in the beam and interact with each other, is studied by means of two-dimensional numerical simulations based on solving a self-consistent set of Vlasov-Maxwell equations. It is shown that, as the focusing magnetic field is decreased, the dynamics of an electron beam with a virtual cathode becomes more complicated due to the formation and interaction of spatiotemporal longitudinal and transverse structures in the interaction region of a vircator. The optimum efficiency of the interaction of an electron beam with the electromagnetic field of the vircator is achieved at a comparatively weak external magnetic field and is determined by the fundamentally two-dimensional nature of the motion of the beam electrons near the virtual cathode.     

ELF in vitro exposure systems for inducing uniform electric and magnetic fields in cell culture media.

Many in vitro experiments on the biological effects of extremely low frequency (ELF) electromagnetic fields utilize a uniform external magnetic flux density (B) to expose biological materials. A significant number of researchers do not measure or estimate the resulting electric field strength (E) or current density (J) in the sample medium. The magnitude and spatial distribution of the induced E field are highly dependent on the sample geometry and its relative orientation with respect to the magnetic field. We have studied the E fields induced in several of the most frequently used laboratory culture dishes and flasks under various exposure conditions. Measurements and calculations of the E field distributions in the aqueous sample volume in the containers were performed, and a set of simple, quantitative tables was developed. These tables allow a biological researcher to determine, in a straightforward fashion, the magnitudes and distributions of the electric fields that are induced in the aqueous sample when it is subjected to a uniform, sinusoidal magnetic field of known strength and frequency. In addition, we present a novel exposure technique based on a standard organ culture dish containing two circular, concentric annular rings. Exposure of the organ culture dish to a uniform magnetic field induces different average electric fields in the liquid medium in the inner and outer rings. Results of experiments with this system, which were reported in a separate paper, have shown the dominant role of the magnetically induced E field in producing specific biological effects on cells, in vitro. These results emphasize the need to report data about the induced E field in ELF in-vitro studies, involving magnetic field exposures. Our data tables on E and J in standard containers provide simple means to enable determination of these parameters.     

Chirped dissipative ion-cyclotron solitons in the Earth’s low-altitude ionospheric plasma with two ion species

Conditions for the excitation of small-scale nonlinear ion-cyclotron gradient-drift dissipative structures in cold ionospheric plasma are considered. The solution for the wave electric field in this structure in the form of a chirped soliton satisfying the equation of the Ginzburg-Landau type is derived in the electrostatic approach. The dissipative structure as a whole represents the chirped soliton accompanied by the comoving quasineutral plasma hump. The possibility of the excitation of two modes of this type (the high- and low-frequency ones) in plasma containing light and heavy ion impurities is considered. The role of electromagnetic corrections and the possible contribution introduced by these structures to the transport processes in the ionosphere are discussed.     

Slipping and tangential discontinuity instabilities in quasi-one-dimensional planar and cylindrical flows

An analytical linear theory of instability of an electron beam with a nonuniform directional velocity (slipping instability) against perturbations with wavelengths exceeding the transverse beam size is offered. An analogy with hydrodynamic instabilities of tangential discontinuity of an incompressible liquid flow is drawn. The instability growth rates are calculated for particular cases and in a general form in planar and cylindrical geometries. The stabilizing effect of the external magnetic field is analyzed.     

Surface structure of ionic liquids under an external electric field

Abstract

Surface structure and properties play an important role in many applications of ionic liquids (ILs). ILs can form unique surface structures that are very different from the bulk. In imidazolium-based ILs, for example, polar groups form ordered layer structure, while cationic alkyl chains are bundled together and point out from the surface. In many applications, ILs work under an external electric field. However, the effect of external electric field on the surface structure of ILs is still not clear. Here by using coarse-grained molecular dynamics simulation, we found that an electric field as strong as 1 V/nm is required to alter the surface structure of 1-dodecyl-3-methylimidazolium nitrate. Under a strong external electric field, layered structure disappears, and instead a sparser, more homogeneous and less orientationally ordered surface develops.     

Plasma equilibrium in 3D magnetic confinement systems and soliton theory

Single-valued conformal flux (magnetic) coordinates can always be introduced on arbitrary toroidal magnetic surfaces. It is shown how such coordinates can be obtained by transforming Boozer magnetic coordinates on the surfaces. The metrics is substantially simplified and the coordinate grid is orthogonalized at the expense of a more complicated representation of the magnetic field in conformal flux coordinates. This in turn makes it possible to introduce complex angular flux coordinates on any toroidal magnetic surface and to develop efficient methods for a complex analysis of the geometry of equilibrium magnetic surfaces. The complex analysis reveals how the plasma equilibrium problem is related to soliton theory. Magnetic surfaces of constant mean curvature are considered to exemplify this relationship.     

Specific features of virtual cathode formation and dynamics with allowance for the magnetic self-field of a relativistic electron beam

The conditions and mechanisms of virtual cathode formation in relativistic and ultrarelativistic electron beams are analyzed with allowance for the magnetic self-field for different magnitudes of the external magnetic field. The typical behavior of the critical current at which an oscillating virtual cathode forms in a relativistic electron beam is investigated as a function of the electron energy and the magnitude of the uniform external magnetic field. It is shown that the conditions for virtual cathode formation in a low external magnetic field are determined by the influence of the magnetic self-field of the relativistic electron beam. In particular, azimuthal instability of the electron beam caused by the action of the beam magnetic self-field, which leads to a reduction in the critical current of the relativistic electron beam, is revealed.     

Channeling of high-power radio waves under conditions of strong anomalous absorption in the presence of an averaged electron heating source

Strong anomalous absorption of a high-power radio wave by small-scale plasma inhomogeneities in the Earth’s ionosphere can lead to the formation of self-consistent channels (solitons) in which the wave propagates along the magnetic field, but has a soliton-like intensity distribution across the field. The structure of a cylindrical soliton as a function of the wave intensity at the soliton axis is analyzed. Averaged density perturbations leading to wave focusing were calculated using the model proposed earlier by Vas’kov and Gurevich (Geomagn. Aéron. 16, 1112 (1976)), in which an averaged electron heating source was used. It is shown that, under conditions of strong electron recombination, the radii of individual solitons do not exceed 650 m.     

Application of magnetic agarose support in liquid magnetically stabilized fluidized bed for protein adsorption

A novel magnetic agarose support (MAS) was fabricated for application in a liquid magnetically stabilized fluidized bed (MSFB). It was produced by water-in-oil emulsification method using a mixture of agarose solution and nanometer-sized superparamagnetic Fe(3)O(4) particles as the aqueous phase. The MAS showed good superparamagnetic responsiveness in a magnetic field. A reactive triazine dye, Cibacron blue 3GA (CB), was coupled to the gel to prepare a CB-modified magnetic agarose support (CB-MAS) for protein adsorption. Lysozyme was used as a model protein to test the adsorption equilibrium and kinetic behavior of the CB-MAS. The dependence of bed expansion in the MSFB with a transverse magnetic field on liquid velocity and magnetic field intensity was investigated. Liquid-phase dispersion behavior in the MSFB was examined by measurements of residence time distributions and compared with that obtained in packed and expanded beds. Dynamic lysozyme adsorption in the MSFB was also compared with those in packed and expanded beds. The dynamic binding capacity at 10% breakthrough was estimated at 55.8 mg/mL in the MSFB, higher than that in the expanded bed (31.1 mg/mL) at a liquid velocity of 45 cm/h. The results indicate that the CB-MAS is promising for use in liquid MSFB for protein adsorption.     

Effect of the external magnetic field on the critical current for the onset of a virtual cathode in an electron beam

The critical current at which an unsteady oscillating virtual cathode forms in an electron beam is studied as a function of the external magnetic field guiding the beam electrons. It is shown that the critical beam current decreases with external magnetic field and that there is an optimum magnetic induction at which the critical current for the onset of an oscillating virtual cathode in the beam is minimum. For a strong guiding magnetic field, the critical beam current is described by relationships derived under the assumption that the motion of the beam electrons is one-dimensional. Such behavior is explained by the characteristic features of the dynamics of the beam electrons in longitudinal and radial directions in the interaction space at different inductions of the external magnetic field.