Latin America multidisciplinary research on heat shock proteins and cell stress: proceedings of the first conference of the Latin America Chapter of the Cell Stress Society International

The First Conference of the Latin America Chapter of the Cell Stress Society International (CSSI) organized by CSSI was held in Montevideo, Uruguay, on March 11–14, 2014. The Latin America Chapter of the CSSI (LAC-CSSI) was established at the Workshop on the Molecular Biology of the Stress Response, Porto Alegre, Brazil, May 2012. The chapter’s first meeting took place in the beautiful city of Montevideo and was chaired by the first (LAC-CSSI) elected president Professor María Bausero. Forty-two invited speakers presented their work to more than 100 scientists. The first day of the conference was dedicated to an introductory program for students, young investigators, and participants new to the field of molecular chaperones and the stress response. These seminars were held in the Pasteur Institute of Montevideo and the Faculty of Sciences of the University of the Republic. These institutions were carefully selected to give foreign participants a broad view of the diversity of students and institutions doing research in Uruguay, as well as an opportunity for direct interaction with our scientists and students. Invited speakers for the seminar series were Dr. Wolfgang Schumann, Dr. Cristina Bonorino, Dr. Antonio De Maio, Dr. Ian Brown, Dr. Rafael Radi, Dr. Daniel Ciocca, and Dr. Celia Quijano. The remaining days of the conference took place at the Sheraton Hotel in Montevideo, and the scientific sessions are discussed below.     

Recent Hydrometeorological Events in the North Atlantic Sector

The gist of Dr Dickson's contribution to the BTO spring conference is contained in this abstract from a joint paper with Professor Lamb, given to the International Commission for the Northwest Atlantic Fisheries (Special Publication No. 8, 1972).     

Biochemical education in Romania: Report on a workshop held in Bucharest, 16–20 September 1991

The Workshop Team from IUBMB consisted of Professor W Rombauts (Leuven, Belgium), Professor F Vella (Saskatoon, Canada), and Dr E J Wood (Leeds, UK), with local arrangements being in the hands of Dr S A Hulea (Secretary of the Romanian Biochemical Society). The Workshop was held at the Institute of Biochemistry, Romanian Academy of Sciences (Head: Professor Dr Cecilia Motas) and there were participants from Bucharest, Constantin, Cluj-Napoca, Galati, Tasi and Sibiu. Support was kindly provided by the Romanian Biochemical Society, World Vision International, The Commission of Biochemistry, Romanian Academy of Sciences, Institute of Biochemistry, University of Medicine and Pharmacy “Carol Davilla”, University of Bucharest, and IUBMB     

Genomics,molecular imaging,bioinformatics, and bio-nano-info integration are synergistic components of translational medicine and personalized healthcare research

Supported by National Science Foundation (NSF), International Society of Intelligent Biological Medicine (ISIBM), International Journal of Computational Biology and Drug Design and International Journal of Functional Informatics and Personalized Medicine, IEEE 7th Bioinformatics and Bioengineering attracted more than 600 papers and 500 researchers and medical doctors. It was the only synergistic inter/multidisciplinary IEEE conference with 24 Keynote Lectures, 7 Tutorials, 5 Cutting-Edge Research Workshops and 32 Scientific Sessions including 11 Special Research Interest Sessions that were designed dynamically at Harvard in response to the current research trends and advances. The committee was very grateful for the IEEE Plenary Keynote Lectures given by: Dr. A. Keith Dunker (Indiana), Dr. Jun Liu (Harvard), Dr. Brian Athey (Michigan), Dr. Mark Borodovsky (Georgia Tech and President of ISIBM), Dr. Hamid Arabnia (Georgia and Vice-President of ISIBM), Dr. Ruzena Bajcsy (Berkeley and Member of United States National Academy of Engineering and Member of United States Institute of Medicine of the National Academies), Dr. Mary Yang (United States National Institutes of Health and Oak Ridge, DOE), Dr. Chih-Ming Ho (UCLA and Member of United States National Academy of Engineering and Academician of Academia Sinica), Dr. Andy Baxevanis (United States National Institutes of Health), Dr. Arif Ghafoor (Purdue), Dr. John Quackenbush (Harvard), Dr. Eric Jakobsson (UIUC), Dr. Vladimir Uversky (Indiana), Dr. Laura Elnitski (United States National Institutes of Health) and other world-class scientific leaders. The Harvard meeting was a large academic event 100% full-sponsored by IEEE financially and academically. After a rigorous peer-review process, the committee selected 27 high-quality research papers from 600 submissions. The committee is grateful for contributions from keynote speakers Dr. Russ Altman (IEEE BIBM conference keynote lecturer on combining simulation and machine learning to recognize function in 4D), Dr. Mary Qu Yang (IEEE BIBM workshop keynote lecturer on new initiatives of detecting microscopic disease using machine learning and molecular biology, http://ieeexplore.ieee.org/servlet/opac?punumber=4425386) and Dr. Jack Y. Yang (IEEE BIBM workshop keynote lecturer on data mining and knowledge discovery in translational medicine) from the first IEEE Computer Society BioInformatics and BioMedicine (IEEE BIBM) international conference and workshops, November 2-4, 2007, Silicon Valley, California, USA.     

National Institute on Drug Abuse genomics consortium white paper: Coordinating efforts between human and animal addiction studies

The National Institute on Drug Abuse Genetics and Epigenetics Cross‐Cutting Research Team convened a diverse group of researchers, clinicians, and healthcare providers on the campus of the University of California, San Diego, in June 2018. The goal was to develop strategies to integrate genetics and phenotypes across species to achieve a better understanding of substance use disorders through associations between genotypes and addictive behaviors. This conference (a) discussed progress in harmonizing large opioid genetics cohorts, (b) discussed phenotypes that are used for genetics studies in humans, (c) examined phenotypes that are used for genetics studies in animal models, (d) identified synergies and gaps in phenotypic analyses of human and animal models and (e) identified strategies to integrate genetics and genomics data with phenotypes across species. The meeting consisted of panels that focused on phenotype harmonization (Dr. Laura Bierut, Dr. Olivier George, Dr. Dan Larach and Dr. Sesh Mudumbai), translating genetic findings between species (Dr. Elissa Chesler, Dr. Gary Peltz and Dr. Abraham Palmer), interpreting and understanding allelic variations (Dr. Vanessa Troiani and Dr. Tamara Richards) and pathway conservation in animal models and human studies (Dr. Robert Hitzemann, Dr. Huda Akil and Dr. Laura Saba). There were also updates that were provided by large consortia (Dr. Susan Tapert, Dr. Danielle Dick, Dr. Howard Edenberg and Dr. Eric Johnson). Collectively, the conference was convened to discuss progress and changes in genome‐wide association studies.     

Weitere Untersuchungen zur Osmoregulation derNitella-Zelle

Ohne ZusammenfassungHerrn Professor Dr. N. Kamiya danke ich herzlich für sein ständiges Interesse und für die Ratschläge bei dieser Arbeit. Herr Professor Dr. J. Kummerow in Santiago (Chile) war bei der Herstellung des Manuskripts behilflich.     

Züchtungsversuche an den symbionten von Pediculus vestimenti burm., nebst physiologischen und morphologischen beobachtungen

Ohne ZusammenfassungHerrn Professor Dr. Paul Buchner in Verehrung gewidmet.Herrn Professor Dr. Anton Koch sei gedankt für die Anregung zu dieser Arbeit. Herrn Professor Dr. Karl v. Frisch danke ich für die Überlassung eines Arbeitsplatzes, Herrn Professor Dr. Hugo Braun für wertvolle Ratschläge.     

Charting a global future for education in physiology

The 2005 Claude Bernard Distinguished Lecture was presented at the XXXV International Congress of Physiological Sciences (IUPS) in San Diego, CA, by Ann J. Sefton. Dr. Sefton is an Emeritus Professor of Physiology of the University of Sydney and co-Chair of the IUPS Education Committee. A full profile of Dr. Sefton is included in this issue's The Physiology Teacher.     

Ultrastructural and morphometric aspects of the juxtaglomerular apparatus in the monkey kidney

Summary The authors describe the ultrastructure of the juxtaglomerular apparatus in five adult male Cebus apella monkeys and communicate morphometric data of the macula densa.In comparison with several species of rodents examined before, the macula cells of the monkey contain many more mitochondria and possess a particularly thick basal membrane. The relative volume of the nuclei is slightly smaller than in rodents.The Goormaghtigh cells of the monkey resemble those of the other animals investigated.The epithelioid (or juxtaglomerular) cells do not contain secretory granules. This observation reminds one of the behavior of the epithelioid cells of guinea pigs.Dedicated to Professor Dr. med. G. Petry (Marburg/Lahn) on the occasion of his 65th birthdayThe authors wish to thank Professor Dr. G. Peters, Head of the Institute of Pharmacology, and Professor Dr. F. Roch-Ramel for kindly having provided the monkey kidneys     

The current status of cardiovascular surgery in the People's Republic of China

Dr. David Bregman was invited to participate in a thirteen-physician American Teaching Delegation led by Dr. Tsung O. Cheng, Professor of Medicine at George Washington University Medical Center in Washington, D.C. The trip was sponsored by the American College of Physicians. Deputy Director of the delegation was Dr. Samuel Asper, Deputy Executive Vice President of the American College of Physicians and Professor of Medicine at Johns Hopkins University. The American Teaching Delegation was the first of its kind to be invited to lecture and impart new medical-surgical techniques throughout the People's Republic of China. The trip lasted approximately one month, from September to October, 1979, and included the September 30 to October 1 celebrations in Peking commemorating the 30th Anniversary of the founding of the People's Republic of China. Principal cities visited were Peking and Shanghai, as well as Chengtu, Chungking, and Wuhan. Dr. Bregman demonstrated, for the first time in the People's Republic of China, intraaortic balloon pumping, a new percutaneous intraaortic balloon, and other cardiac assist techniques.     

Forest ecosystem genomics and adaptation: EVOLTREE conference report

This article is a summary report of the international conference "Forest ecosystem genomics and adaptation" organized by the EVOLTREE Network of Excellence in San Lorenzo de El Escorial (Madrid), Spain, from 9 to 11 June 2010. Main achievements and results of the network are presented for the eight thematic sessions and a stakeholder session. The conference has shown that adaptive responses of trees to biotic or abiotic selection pressures can now be investigated at the gene level for traits of adaptive significance. Candidate genes have been catalogued for phenological and drought-related traits in important tree families (Salicaceae, Fagaceaea and Pinaceae), and their variation in natural populations is being explored. Genomics can now be integrated in ecological research to investigate evolutionary response to climate changes in a wide range of species. New avenues of research were also highlighted as the exploration of gene networks involved in adaptive responses and the combination of experimental and modelling approaches to disentangle components of evolutionary changes triggered by climate change. The main focus of the conference was the adaptation of trees to environmental changes. The conference was organized in eight thematic sessions ranging from genomic approaches aiming at identifying genes of adaptive significance to practical issues regarding mitigation options for combating climate change. A dialogue between scientists and end users took place in the form of an ad hoc stakeholder session. A panel of end users from various forest and policy-making institutions expressed their expectations, and the discussions with the scientists addressed the potential applications of research findings to the management of genetic resources in the context of climate changes. The conference was introduced by two keynote speakers Dr. Pierre Mathy from the European Commission, Directorate General of Research, and Dr. Allen Solomon, former National Program Leader for Global Change, US Forest Service. All the thematic sessions were introduced by high-level invited speakers from the respective fields.     

The European Proteomics Association (EuPA) is in the field. Report of the formal inauguration of the European Proteome Association (Munich, Germany, August 29, 2005)

After one year of preparation the European Proteomics Association (EuPA) was formally inaugurated on August 29, 2005, on the occasion of the 4(th) HUPO World Congress in Munich, Germany. Delegates from 16 European countries elected Dr. Friedrich Lottspeich, President of the German Proteome Society, as the first EuPA President. The EuPA Board also comprises Professor Mathias Uhlen as Vice President, along with Professor Michael Dunn (Ireland), Professor Concha Gil (Spain), Dr. Jean Charles Sanchez (Switzerland) and Professor Pier Giorgio Righetti (Italy) as Coordinators for the presently defined focus activities of the EuPA. The general objectives of the EuPA are to promote proteomic activities throughout Europe, emphasising the benefits and contribution of proteomics to biological researchers, industry, the general public and politicians.     

Beitrag zur Biologie der Gewebezellen

Ohne ZusammenfassungIch spreche Herrn Professor Dr. med.Th. Rovsing meinen verbindlichsten Dank für die Erlaubnis aus, das menschliche Sarkommaterial von der Chirurgischen Klinik zu benutzen, Herrn Professor Dr. med.V. Ellermann dafür, da\ er mir dasRoussche Hühnersarkom zum Geschenk machte, Herrn Geheimrat Professor Dr.Blumenthal und Professor Dr. phil.Rh. Erdmann dafür, da\ sie mir trockenes Material desRousschen Sarkoms und dasFlexner-Joblingsche Rattencarcinom zur Verfügung stellten.     

Four Children and Yale: The Making of a Human Geneticist: The Grover Powers Lecture 2014

Dr. Leon E. Rosenberg delivered the following presentation as the Grover Powers Lecturer on May 14, 2014, which served as the focal point of his return to his “adult home” as a Visiting Professor in the Department of Pediatrics. Grover F. Powers, MD, was one of the most influential figures in American Pediatrics and certainly the leader who created the modern Department of Pediatrics at Yale when he was recruited in 1921 from Johns Hopkins and then served as its second chairman from 1927 to 1951. Dr. Powers was an astute clinician and compassionate physician and fostered and shaped the careers of countless professors, chairs, and outstanding pediatricians throughout the country. This lectureship has continued yearly since it first honored Dr. Powers in 1956. The selection of Dr. Rosenberg for this honor recognizes his seminal role at Yale and throughout the world in the fostering and cultivating of the field of human genetics. Dr. Rosenberg served as the inaugural Chief of a joint Division of Medical Genetics in the Departments of Pediatrics and Internal Medicine; he became Chair when this attained Departmental status. Then he served as Dean of the Medical School from 1984 to 1991, before he became President of the Pharmaceutical Research Institute at Bristol-Myers Squibb and later Senior Molecular Biologist and Professor at Princeton University, until his recent retirement. Dr. Rosenberg has received numerous honors that include the Borden Award from the American Academy of Pediatrics, the McKusick Leadership Award from the American Society for Human Genetics, and election to the Institute of Medicine and the National Academy of Sciences.     

Protoplasmatische Anatomie des Laubmooses Bryum capillare. I

Ohne ZusammenfassungDie Arbeit wurde am Pflanzenphysiologischen Institut der Universität Wien ausgeführt. Dem Vorstand des Institutes Herrn Professor Dr. Karl Höfler erlaube ich mir für die Anregung der Arbeit und die ständige Leitung der Untersuchungen meinen herzlichsten Dank auszusprechen. Für die Einführung in die Fluoreszenzmikroskopie bin ich Herrn Professor Dr. Christian Wimmer (Mödling) zu Dank verpflichtet. Herrn Dr. Lothar Hofmeister danke ich für seine ständige Hilfsbereitschaft herzlichst.     

An investigation of the cochlear microphonic response of two species of echolocating bats:Rousettus aegyptiacus (geoffroy) andPipistrellus pipistrellus (Schreber)

Summary The cochlear microphonic (CM) responses of two species of echolocating bats:Rousettus aegyptiacus andPipistrellus pipistrellus have been investigated (Figs. 1 and 3) and the responses have been shown to have a single major peak corresponding with the lower range of frequencies produced in echolocation.My thanks are due to Professor Don R. Arthur for providing laboratory facilities for this work and Dr. J. D. Pye for advice during this study and for much valuable unpublished information on calls produced by the bats in this study, and also to Dr. P. Racey for the pipistrelles. This research was made possible by a Science Research Council grant and was sponsored in part by the Air Force Office of Scientific Research under contract number AF61(052)-876 to Dr. Pye. The author was a Harold Row student of King's College.     

Zur Frage des Plasmalemmas bei Desmidialen

Ohne ZusammenfassungEs sei mir gestattet, meinem Lehrer, Herrn Professor Dr. Karl Höfler, für die Anregung zu dieser Arbeit zu danken. Herrn Professor Dr. Helmut Kinzel gilt mein Dank für seine Betreuung und für experimentelle Hinweise, Herrn Dr. Karl Burian für die Diskussion und Durchsicht des Manuskripts; Herr Dr. Klaus Kowallik verfertigte mir freundlicherweise die Zeichnungen.