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1.
The need for the integration of the assessment of human and ecological risks in contaminated areas, such as derelict mines, widely increases. The risk assessment process is becoming a powerful tool to provide sound scientific bases for decision-making processes. In Portugal, the risk assessment process is in its early years and the lack of multidisciplinary teams of experts is frequently mentioned as the main obstacle to its implementation. Therefore, the majority of the reclamation actions are based on impact assessment studies that usually are characterized by few biological and toxicological considerations. In order to account for some of these constraints, the ecological risk assessment framework proposed by the U.S. Environmental Protection Agency was used to plan the assessment of human and ecological risks posed by the high concentrations of metals scattered in the vicinity of S. Domingos mine, a cuprous pyrite mine located in the Southeast Alentejo (Portugal). This study presents the problem formulation phase of the assessment. It includes all the scientific information available for the area, a conceptual model, and an analysis plan for the risk assessment process. Following a tiered approach, several tasks were planned in order to acquire chemical, toxicological, and ecological information, in order to compensate for the lack of toxicity data for site-specific species. 相似文献
2.
This study examined the bioaccumulation of key metals and other contaminants (SO 4, F, Na, K, Ca, Mg, P, Si, Fe, Mn, Zn, Ni, Co, Cu, and Cd) by seaweeds from the Egyptian Mediterranean Sea coast and their risk to human health. Bioaccumulation factor calculations indicated that S, F, Na, K, Zn, Cu, and Cd had high seaweed uptake and this referred to the potential pollution of the coastal area. Multivariate analysis of the studied contaminants confirmed the bioaccumulation factor results as well as the physiological processes in seaweeds. Human health risk assessment of F, Mn, Zn, Ni, Cu, and Cd was conducted using hazard quotient (HQ) and incremental lifetime cancer risk (ILCR) analyses. The carcinogenic assessment of sediments and ingestion of seaweeds using ILCR calculations revealed that Mn, Ni, and Cd in sediments and F and Zn in seaweeds require remedial action in order to reduce their human health risks. Additionally, HQ calculations for the contaminants in seaweeds and reference to toxicological references values from different agencies revealed that F and Co present high human health risk effects. Consequently, the potential public health risks from dietary exposure to hazardous contaminants in seaweeds must be continually subjected to research, regulation, and debate. 相似文献
3.
A symposium was conducted in April 1998 by the U.S. Environmental Protection Agency's National Health and Environmental Effects Research Laboratory (NHEERL) to explore issues of extrapolation in human health and ecological risk assessments. Over the course of three and one half days, leading health and ecology experts presented and discussed research methods and approaches for extrapolating data among taxa and across levels of biological organization, through time, and across spatial scales. The intended result of this symposium was enhanced interaction among a diverse array of scientists, policymakers, and risk assessors to promote identification of approaches for reducing the uncertainties of extrapolation in risk assessment. 相似文献
4.
The aim of this study was to investigate the environmental impact and the human health risks associated with metals exposure in the Catalan stretch of the Ebro River, Spain. The concentrations of the following elements were determined in soils and tap water: As, Cd, Cr, Cu, Hg, Mn, Ni, and Pb. Carcinogenic and non-carcinogenic risks were separately assessed for adults and children. Relatively low metal concentrations in tap water were found. It indicates that water intake is not a relevant source of metals for human health impact in the area under evaluation. In turn, the levels of metals in soils were similar or less than those found in a number of recent worldwide surveys. The presence of industrial facilities located upstream the Ebro River, including a chloralkali plant, should not mean additional non-carcinogenic risks for the population living in the area. The results of the current study allow us to establish that the concentrations of most carcinogenic elements (with the exception of As) should not mean potential health risks for the local population. However, because of the relatively high levels of geological origin found for As, a continued monitoring of these elements would be desirable. 相似文献
5.
Food consumption is one of the main routes of human exposure to organochlorine pesticide residues (OCPRs). To assess the potential health risks associated with OCPRs contaminants due to freshwater organism consumption, a number of vegetables, prawn, snail, and fish were collected from Khlong 7 (canal), Rangsit agricultural area, Pathum-Thani Province, Thailand. The samples were extracted using a multiresidue extraction method and then analyzed by gas chromatography with microelectron capture detector (μ -ECD). The results show that low concentrations of OCPRs were detected in parts per billion (ppb) levels. Based on a plausible worst-case scenario, the local population could be at risk for cancer due to consumption of fish contaminated by α -, β -HCH, heptachlor, heptachlor epoxide, aldrin, dieldrin, DDD, DDE, and DDT. Likewise, individuals may be at risk from consumption of Lanchester's freshwater prawn Macrobrachium lanchesteri, freshwater snail Filopaludina mertensi, swamp morning-glory Ipomomea aquatica, neptunia Neptunia oleracea, and water lily Nymphaea lotus because these species all contained elevated concentrations of α -, β -HCH, heptachlor, heptachlor epoxide, aldrin, and dieldrin. 相似文献
6.
Organochlorine pesticides (OCPs) used in agriculture and for public health purposes were banned in Thailand over the past decade; however, their persistent residues have been found in several agricultural areas of the country. This may result in adverse effects to human populations. This study investigated the concentration of organochlorine pesticides residues (OCPRs) in surface water and evaluated the potential cancer risk associated with dermal contact of the local fisherman fishing in the Khlong 7 canal, Rangsit agricultural area, central Thailand. Water samples were extracted using liquid-liquid extraction (LLE) and then analyzed by gas chromatography with microelectron capture detector (μ -ECD). The results show that low concentrations of OCPRs were detected in parts per billion (ppb or ng/ml) levels, that is, ∑ Endosulfan (α -, β -, and -sulfate) 0.082 ng/ml > DDT and derivatives 0.019 ng/ml > ∑ HCH (α -, γ -, β -, and δ -HCH) 0.014 ng/ml > aldrin and dieldrin 0.007 ng/ml > heptachlor and heptachlor epoxide 0.0068 ng/ml > endrin and endrin aldehyde 0.005 ng/ml > methoxychlor 0.001 ng/ml, respectively. Using the worst-case scenario defined as the reasonable maximum exposure (RME) to assess the potential cancer risk, five OCPs (dieldrin, 4,4′ -DDT, β -HCH, heptachlor, and heptachlor epoxide) may pose a risk of concern on a lifetime human carcinogenesis greater than one in a million. 相似文献
7.
A method for deriving Site-Specific Assessment Criteria (SSAC) for use when considering risk to human health from chronic exposure to heavy metals (except lead), metalloids, and organic substances in soil, with application to the United Kingdom (UK), is described. The SSAC represents the soil concentration above which an unacceptable risk to human health may be indicated. The method considers the UK standard land uses (residential with and without plant uptake, allotment gardens, and commercial/industrial) by applying the default exposure factors and algorithms provided. Non-standard land uses can be also considered. Site-specific determinations of contaminant bioaccessibility or of plant-to-soil concentration factors may be used if available. The method adopts the risk-based source-pathway-receptor pollutant linkage framework and a deterministic methodology. Exposure pathways considered are direct ingestion of soil and dust, consumption of home grown or allotment vegetables, ingestion of soil attached to such vegetables, inhalation of soil vapors outdoors and inhalation of soil vapors indoors. A test for the significance of the dermal pathway is also included. It is not intended that the method be used to generate or replace UK Soil Guideline Values, because this can only be done by the appropriate authoritative bodies within the UK (Department of the Environment, Food and Rural Affairs and the Environment Agency). 相似文献
8.
Assessment of risk to public health or environmental resources requires competent characterization of stressors and corresponding effects. Because of the complexity of most stressor-response relationships, it is impossible to completely characterize all the variables, so a select set of measurements is made to reflect the most critical components. Such measurements, or indicators, are included in monitoring programs to estimate trend, stressor source, or magnitude of effects and lead to thresholds for management action or restoration. Although a wide variety of programs and program objectives exists, there are some common challenges for indicator development, including a strong link to management actions. Indicator measurements used in U.S. Environmental Protection Agency (USEPA) risk assessment activities must stem from collaboration among managers, risk assessors, scientists and stakeholders. The primary objective of the USEPA's Fifth Symposium of the National Health and Ecological Effects Research Laboratory was to improve health and ecological risk assessment through dedicated sessions that maximized interaction and discussion among these groups. Existing measurements were challenged for appropriateness, efficiency and scientific validity. Emerging science was explored for greater understanding, better interpretation, and improved methodology. A secondary objective was to uncover and exploit common indicators and supporting data for human health and ecological models. 相似文献
9.
Due to accelerated urbanization and reform of industrial structure in China, polluting industries in major cities have been closed or relocated. Consequently, large numbers of industrial sites were generated and the contaminated soils on and around these sites may pose risks to humans. This case study presents an estimation of human health risks for an area that is mainly impacted through air dispersion and deposition from a large-scale metallurgical refinery complex in Zhuzhou city, Hunan Province, China. Carcinogenic and non-carcinogenic risks posed by the contaminants were estimated under future industrial and residential land use scenarios. The result shows that adverse health effects may occur primarily through ingestion of soils contaminated with As, Cd, and Pb. The total carcinogenic risks of multiple contaminants for a large area exceed the acceptable risk level of 1 × 10 ?5, and several localized hotspots, where the total hazard index exceeds 1 were identified. Soils in the Tongda site pose the highest carcinogenic risks and non-carcinogenic hazards. It is concluded that potential human health risks exist under the proposed redevelopment scenarios, and development of risk-based remediation strategies is recommended. 相似文献
10.
The aim of the study is to assess the probabilistic non-cancer and cancer risks by recreational bathing in Tres Arroyos creeks (southeastern Buenos Aires Province, Argentina). In these waters, hazardous substances (heavy metals, pesticides) have been detected, possibly related to agricultural activities. To assess such risk, USEPA models in aggregated (exposure through accidental oral water intake and dermal contact simultaneously) and cumulative approaches (combined exposure to more than one substance) were applied, performed for bathers of 5, 10, 15, and 20 years old. The results show that chronic bathing in these waters is not harmful at the concentrations and the exposure scenarios considered. Arsenic was the riskiest substance for both non-cancer and cancer effects, affecting mainly the youngest age group, and the accidental water intake during bathing was the most relevant pathway of exposure. On the other hand, the study highlights the key role of the frequency and duration of the bath event. We discuss the results in light of a previous paper of our authorship concluding that the health risk assessment is a valid alternative to analyze recreational water quality, which, unfortunately, is unused by water management agencies in Argentina. 相似文献
12.
This article evaluates the health risk raised by exposure to naturally occurring radionuclides in soil around Khak-Sefid, Ramsar, Iran, which is an area of high natural background radiation. A high purity germanium detector was used to determine levels of radionuclides in soil samples and the cancer morbidity risk for a hypothetical resident farmer was evaluated using the RESidual RADioactivity (RESRAD) code. The average activity concentrations of 226Ra, 232Th, and 40K were found to be 13,201 ± 391, 27.9 ± 2.4, and 415.5 ± 16 Bq/kg, respectively. The maximum assessed cancer morbidity risks were calculated from external and internal exposure pathways as 4.73 × 10 ?2 and 3.40 × 10 ?2 for 226Ra, 1.41 × 10 ?4 and 7.88 × 10 ?5 for 232Th, and 1.3 × 10 ?4 and 4.233 × 10 ?4 for 40K. The RESRAD calculations also showed total cancer morbidity risks from external gamma and plant ingestion pathways were more important than from other exposure pathways. A sensitivity analysis was also performed to determine the input parameter values in the risk assessment process. In general, due to the high calculated risk of 226Ra compared with 232Th and 40K it can be the major source of concern for human heath in the study area. 相似文献
13.
Chromated copper arsenate (CCA) is a chemical preservative used to treat wood for a variety of outdoor uses, including decks, fencing, and play structures. This article describes a methodology to quantify exposures to arsenic from CCA-treated wood. Exposure was evaluated for ingestion and dermal contact with arsenic-containing residue on treated wood surfaces (dislodgeable arsenic), and ingestion, dermal contact, and inhalation of soil containing arsenic originating from treated wood structures. Standard approaches were used to quantify exposures to arsenic in soil. In the absence of standard approaches for exposures to dislodgeable residue, an empirical approach was developed, extrapolating from studies of soil loadings on hands and soil ingestion rates to estimate the amount of dislodgeable residue on hands that is subsequently ingested. Results from animal studies were used to develop relative bioavailability estimates for dislodgeable and soil arsenic. A focused sensitivity analysis demonstrated that the assumptions used regarding hand loading and subsequent incidental ingestion of dislodgeable arsenic had the most significant impact on the results. This assessment indicates low uptake of arsenic into the body, resulting in incremental lifetime cancer risks within USEPA's target risk levels. We compare this approach to other methodologies used to assess exposures to treated wood. 相似文献
14.
Recognizing the need to enhance the effectiveness and efficiency of risk assessments globally, the World Health Organization's International Programme on Chemical Safety, the U.S. Environmental Protection Agency, the European Commission, and the Organization for Economic Cooperation and Development developed a collaborative partnership to foster integration of assessment approaches used to evaluate human health and ecological risks. The objectives of this effort included: improving understanding of the benefits of integration, identifying obstacles to the integration process, and engaging key agencies, organizations, and scientific societies to promote integration. A framework with supporting documentation was developed to describe an approach for integration. Four case studies were constructed to illustrate how integrated risk assessments might be conducted for chemical and nonchemical stressors. The concepts and approaches developed in the project were evaluated in an international workshop. The goal of this effort was international acceptance of guidance for integrated risk assessment. 相似文献
15.
Human health risk assessment, whether at the screening level or more complex phase, is not an exact science. A wide variety of advice and direction is offered by international, national, and provincial/state environmental agencies regarding the conduct of risk assessment, and different risk assessors access and rely on the available regulatory advice and direction differently. This may result in wide variability in the estimates of chemical exposure and risk. A comparison of human health risk assessment approaches practiced at the provincial level in Canada was undertaken, wherein each jurisdiction's approach was applied to a hypothetical contaminated site. Approaches were found to vary both in terms of methodological considerations, and in matters of policy. The exercise yielded results in terms of estimated exposures and predicted hazard quotients/indexes and incremental lifetime cancer risks that were in some cases quite consistent (varying by a factor of less than 1.5 times), and in other cases remarkably different (varying by orders of magnitude). This article reviews the various approaches/frameworks applied and discusses the results of the hypothetical risk assessments, in terms of both the observed variation and the source of this variability. 相似文献
16.
Del Azul creek (Argentina) is a natural water body used for recreational bathing in which heavy metals and pesticides have been detected. The aim of the study is to estimate the probabilistic non-cancer and cancer risks by recreational bathing, applying U.S. Environmental Protection Agency models for aggregated (exposure through accidental oral intake of water and dermal contact) and cumulative risks (combined exposure to groups of substances) for bathers of 5, 10, 15, and 20 years old. Bathing in Del Azul creek does not generate risks at the concentrations and the exposure scenarios considered. Cypermethrin and arsenic and heptachlor were the riskiest non-cancer and cancer substances, respectively. Our study highlights the importance of considering both routes of exposure because of the great significance of the dermal route and because of the variability of population characteristics, as it has been stated in other studies. These considerations are highly significant for Argentina, where the quality of recreational water for other than microbiological causes is frequently evaluated based only on the harmful oral intake and applied to a hypothetical individual representative of the population. 相似文献
17.
Soil contamination with heavy metals is one of the main environmental concerns in China, mainly owing to rapid industrialization and mining activities in certain areas. The current study aimed at monitoring the levels of heavy metals in soils of the industrial areas along the Jinxi River and surrounding Lake Qingshan. In addition, a health risk assessment for humans in contact with these soils was also conducted. The results revealed that the soils of the studied areas were contaminated with Cr, Cu, As, Se, Cd, Pb, and Zn and that the industrial activities were the main source of soil contamination therein. Furthermore, soils of the sites adjacent to Lin’an city exhibited higher levels of heavy metals than the upstream and Lake Qingshan sites. Most of the studied heavy metals tended to concentrate in the fine soil fractions (PM100, PM10, and PM2.5). Calculation of the hazard index (HI) revealed that humans, especially children, have potential health risks. Moreover, As was found to contribute to more magnitude of cancer risks. Thus, we concluded that the unmanaged development negatively affects the Chinese environment and human health. Furthermore, fine fractions of soil particles should be considered for risk assessment. 相似文献
18.
以沈阳某冶炼厂废弃厂区重金属污染监测为依据,采用美国环保局最新的人类健康风险评价标准方法对沈阳某冶炼厂废弃地块污染土壤进行了评价,并且假设未来该土地利用类型为工业用地(Ⅰ)或休闲用地(Ⅱ).评价结果显示:工业用地(Ⅰ)和休闲用地(Ⅱ)的累积非致癌风险指数分别为2.65×10-2和3.67×10-2;工业用地(Ⅰ)和休闲用地(Ⅱ)由呼吸摄入Cd造成的潜在致癌风险指数分别为4.48×10-9和7.30×10-10,不会对在该地区工作和休闲的人们造成身体健康上的伤害;无论是工业用地假设还是休闲用地假设,由无机铜造成的人类健康风险在整个风险中所占的比例最大;由美国环保局的人类健康风险评价方法反推得出的冶炼厂地块未来为工业用地的土壤修复目标值均小于我国工业企业土壤环境质量风险评价基准值. 相似文献
19.
Human health risks due to exposure of heavy metals in the atmospheric air of Tomsk, Russia, were studied. The concentrations of 22 metals in the ambient air were calculated on the basis of the ICP–MS experimental determination of their contents in the insoluble fraction of snow cover. Non-carcinogenic hazards were estimated for the areas of power plant (“Zone PP”), brickworks location (“Zone BF”), zone influenced by concrete product plants (“Zone CP”), and petrochemical plant suburbs (“Zone PCP”). Manganese, Al, Cu, and Ba make the largest contribution to the integral non-cancer hazard caused by chronic inhalation intake in all areas. Zinc is added to the above listed elements in the “Zone PP” and V, Co, Cr, and Ni in the “Zone BF” are also added. Densely populated residential areas “Zone BF” and “Zone PP” were characterized by the higher levels of diseases risks associated with human inhalation intake of metals in comparison with other areas. The dust load should be primarily decreased in the zones subjected to harmful effects of brick factories and other construction materials. As to the power station, the portion of natural gas in consumption should increase from year to year for decreasing heavy metal emissions from burning of coal. 相似文献
20.
The goal of this article is to present the Human Health Risk Assessment (HRA) software developed as one of the NORISC 1 1NORISC is the acronym of the project “Network Oriented Risk assessment by In-situ Screening of Contaminated sites” realized under under the 5th European Union Community Framework Programme for Research, Technological Development and Demonstration Activities. View all notes decision support software system components that could be used as a tool for facilitating management of urban contaminated sites. The NORISC-HRA software provides sufficient technical and procedural support to conduct a simple site-specific risk assessment. The employed HRA methodology is generally based on U.S. Environmental Protection Agency (USEPA) procedures. The software determines the level and spatial distribution of human health risks at a given site and sets up site-specific preliminary Health-Based Remedial Goals (HBRGs)/Risk-Based Concentrations (RBCs) for soil and groundwater. The NORISC-HRA software is recommended for use when national soil and groundwater limit values are exceeded. Exposure pathways considered in this software are associated with three land use patterns—residential, industrial/commercial, and recreational. The aricle also presents the software testing results obtained at one of the NORISC test sites—the Massa site (Avenza-Carrara, Tuscany, Italy). Findings of the HRA indicated that the contaminated soil at the Massa test site might pose potential cancer and non-cancer risks to industrial workers in its present condition. Arsenic was the dominant substance responsible for most of the baseline risk and at the RBC of 1.77 mg/kg it was the primary driver of remedial decisions at the Massa site. 相似文献
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