共查询到20条相似文献,搜索用时 31 毫秒
1.
Fin ZJ Cai Sue Lester Tim Lu Helen Keen Karyn Boundy Susanna M Proudman Anne Tonkin Maureen Rischmueller 《Arthritis research & therapy》2008,10(2):R31
Introduction
The aim of this study was to compare cardiovascular autonomic nervous system function in patients with primary Sj?gren's syndrome (pSS) with that in control individuals, and to correlate the findings with autonomic symptoms and the presence of exocrine secretory dysfunction. 相似文献2.
Luke C Henry Sébastien Tremblay Suzanne Leclerc Abdesselam Khiat Yvan Boulanger Dave Ellemberg Maryse Lassonde 《BMC neurology》2011,11(1):105
Background
Despite negative neuroimaging findings many athletes display neurophysiological alterations and post-concussion symptoms that may be attributable to neurometabolic alterations. 相似文献3.
Marieke Biegstraaten Ivo N van Schaik Wouter Wieling Frits A Wijburg Carla EM Hollak 《BMC neurology》2010,10(1):38
Background
Fabry patients have symptoms and signs compatible with autonomic dysfunction. These symptoms and signs are considered to be due to impairment of the peripheral nervous system, but findings indicative of autonomic neuropathy in other diseases, such as orthostatic intolerance and male sexual dysfunction, are infrequently reported in Fabry disease. The aim of our study was to investigate autonomic symptoms and cardiovascular autonomic function in a large cohort of male and female Fabry patients. 相似文献4.
Kari Todnem Ralf Peter Michler Tony Eugen Wader Morten Engstr?m Trond Sand 《BMC neurology》2009,9(1):52
Background
This study aimed to explore the value of extended motor nerve conduction studies in patients with ulnar nerve entrapment at the elbow (UNE) in order to find the most sensitive and least time-consuming method. We wanted to evaluate the utility of examining both the sensory branch from the fifth finger and the dorsal branch of the ulnar nerve. Further we intended to study the clinical symptoms and findings, and a possible correlation between the neurophysiological findings and pain. 相似文献5.
Eriksson C Kokkonen H Johansson M Hallmans G Wadell G Rantapää-Dahlqvist S 《Arthritis research & therapy》2011,13(1):R30
Introduction
Autoantibodies have a central role in systemic lupus erythematosus (SLE). The presence of autoantibodies preceding disease onset by years has been reported both in patients with SLE and in those with rheumatoid arthritis, suggesting a gradual development of these diseases. Therefore, we sought to identify autoantibodies in a northern European population predating the onset of symptoms of SLE and their relationship to presenting symptoms. 相似文献6.
Background
Behavioural and psychological symptoms of dementia (BPSD) are non-cognitive symptoms commonly associated to Alzheimer's disease (AD). The characterization of the clinical profile of AD patients might help to better understand disease evolution and to improve diagnosis and treatment. Thus, the aim of the present study is to describe the clinical profile of AD patients, and to correlate the presence of BPSD with the severity of the disease. 相似文献7.
Linda Engblom Lena Eliasson-Selling Nils Lundeheim Katinka Belák Kjell Andersson Anne-Marie Dalin 《Acta veterinaria Scandinavica》2008,50(1):25
Background
The aim of this study was to get information on post mortem diagnoses of sows found dead or euthanised and to understand the diagnoses aetiology (causative background). Moreover, the study was to evaluate the association between the clinical symptoms observed on farm and post mortem findings. 相似文献8.
Background
Parkinsonian symptoms have been associated with increased morbidity and mortality. Several studies have reported on the prevalence of signs and symptoms. Symptoms questionnaires can identify potential PD cases for further neurological examination to save resources. They can also provide information about how much of the population reports specific signs and symptoms. The objective of the study was to determine the self-reported prevalence of parkinsonian symptoms from a questionnaire, and to examine their association with age and self-reported Parkinson's disease in a large cohort.Methods
A cross-sectional study was conducted within a sub-cohort of the EPIC-Norfolk (European Prospective Investigation of Cancer) cohort study.Results
The prevalence of six self-reported parkinsonian symptoms are reported for 11539 individuals who answered all symptoms questions (62% of sub-cohort): rest tremor (4%), difficulty starting to walk (4%), difficulty getting out of a chair (6%), slower walking (34%), smaller handwriting (micrographia- 9%), and less acute sense of smell (olfactory dysfunction- 9%). The presence of individual symptoms increased with age except for difficulty getting out of a chair.Conclusion
The results support previous findings that the presence of self-reported parkinsonian symptoms is strongly associated with age and self-reported PD diagnosis. The data also provide information regarding the prevalence of symptoms in a large, younger population of adults than previously reported in the literature.9.
Duncan D Atherton Paul Facer Katherine M Roberts V Peter Misra Boris A Chizh Chas Bountra Praveen Anand 《BMC neurology》2007,7(1):21
Background
The Contact Heat Evoked Potential Stimulator (CHEPS) rapidly stimulates cutaneous small nerve fibres, and resulting evoked potentials can be recorded from the scalp. We have studied patients with symptoms of sensory neuropathy and controls using CHEPS, and validated the findings using other objective measures of small nerve fibres i.e. the histamine-induced skin flare response and intra-epidermal fibres (IEF), and also quantitative sensory testing (QST), a subjective measure. 相似文献10.
Background
Setting the rules for the identification of a stable conformation of a protein is of utmost importance for the efficient generation of structures in computer simulation. For structure prediction, a considerable number of possible models are generated from which the best model has to be selected. 相似文献11.
12.
Yoshiko Miyaoka Yoshie Akimoto Kayoko Ueda Yuri Ujiie Machiko Kametani Yoko Uchiide Toshiko Kamo 《BioPsychoSocial medicine》2011,5(1):5
Background
Some women with depressive disorders experience severe premenstrual symptoms. However, there have been few studies in which premenstrual symptoms in women suffering from depressive disorders were assessed. In this study, we aimed to investigate premenstrual symptoms in women with depressive disorders using the premenstrual dysphoric disorder (PMDD) scale. 相似文献13.
Background
Urinary incontinence (UI) is a distressing problem for older people. To investigate the relationship between UI and respiratory symptoms among middle-aged and older men, a community-based study was conducted in Japan.Methods
A convenience sample of 668 community-dwelling men aged 40 years or above was recruited from middle and southern Japan. The International Consultation on Incontinence Questionnaire-Short Form, the Medical Research Council's dyspnoea scale and the Australian Lung Foundation's Feeling Short of Breath scale, were administered by face-to-face interviews to ascertain their UI status and respiratory symptoms.Results
The overall prevalence of UI was 7.6%, with urge-type leakage (59%) being most common among the 51 incontinent men. The presence of respiratory symptoms was significantly higher among incontinent men than those without the condition, especially for breathlessness (45% versus 30%, p = 0.025). The odds of UI for breathlessness was 2.11 (95% confidence interval 1.10-4.06) after accounting for age, body mass index, smoking and alcohol drinking status of each individual.Conclusions
The findings suggested a significant association between UI and breathlessness in middle-aged and older men. 相似文献14.
Carol Iversen Lee Lancashire Michael Waddington Stephen Forsythe Graham Ball 《BMC microbiology》2006,6(1):28-8
Background
Enterobacter sakazakii is an emergent pathogen associated with ingestion of infant formula and accurate identification is important in both industrial and clinical settings. Bacterial species can be difficult to accurately characterise from complex biochemical datasets and computer algorithms can potentially simplify the process. 相似文献15.
Mostafa A. Yehia Tarek S. El-Ammawi Khairia M. Al-Mazidi Mahmoud A. Abu El-Ela Hejab S. Al-Ajmi 《Mycopathologia》2010,169(4):241-246
Background
Fungal infections constitute a major health problem all over the world. Signs and symptoms induced by various dermatophytic infections are difficult to distinguish clinically from each other. So, characterization by in vitro culture is required for appropriate diagnosis and treatment as well as to study the epidemiological characteristics in a region. 相似文献16.
Nagisa Sugaya Shuhei Izawa Namiko Ogawa Kentaro Shirotsuki Hitomi Kobayashi Kosuke C Yamada Hideki Tsumura Shinobu Nomura Hironori Shimada 《BioPsychoSocial medicine》2010,4(1):2
Introduction
The hypothalamic-pituitary-adrenal axis is known to be related to abdominal symptoms, and the relationship between abdominal pain and cortisol secretory patterns has been previously investigated using a cross-sectional approach. Here, we investigated the effect of day-to-day variations in salivary cortisol and dehydroepiandrosterone-sulfate levels on abdominal symptoms in healthy individuals. 相似文献17.
Andre Kemmling Thomas Duning Lars Lemcke Thomas Niederstadt Jens Minnerup Heike Wersching Martin Marziniak 《BMC neurology》2010,10(1):80
Background
The syndrome of the sinking skin flap (SSSF) with delayed sensorimotor deficits after craniectomy is not well known and often neglected. Among various postulated causes, there is evidence that disturbed brain perfusion may be related to the observed symptoms, and that cranioplasty reliably alleviates these symptoms. We report a case of sinking skin flap syndrome (SSFS) with recovery from neurological sensorimotor deficits after cranioplasty correlated with pre- and postsurgical MR brain perfusion studies. 相似文献18.
Background
Protection of pigs by vaccination against Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is hampered by the presence of 15 different serotypes. A DIVA subunit vaccine comprised of detergent-released proteins from A. pleuropneumoniae serotypes 1, 2 and 5 has been developed and shown to protect pigs from clinical symptoms upon homologous and heterologous challenge. This vaccine has not been characterized in-depth so far. Thus we performed i) mass spectrometry in order to identify the exact protein content of the vaccine and ii) cross-serotype 2-D immunoblotting in order to discover cross-reactive antigens. By these approaches we expected to gain results enabling us to argue about the reasons for the efficacy of the analyzed vaccine. 相似文献19.
Christian Tanislav Ralf Siekmann Nicole Sieweke Jens Allendörfer Wolfgang Pabst Manfred Kaps Erwin Stolz 《BMC neurology》2011,11(1):69-5
Background
Cerebral venous thrombosis (CVT) is a disease with a wide spectrum of symptoms and severity. In this study we analysed the predictive value of clinical signs and symptoms and the contribution of D-dimer measurements for diagnosis. 相似文献20.
Grzegorz Woźniakowski Elżbieta Samorek-Salamonowicz Wojciech Kozdruń 《Acta veterinaria Scandinavica》2011,53(1):10