共查询到20条相似文献,搜索用时 15 毫秒
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Genes of Arabidopsis thaliana, Orysa sativa, Caenorhabditis elegans, Homo sapiens have been studied by computer analysis. The average intron and exon lengths in genes of these organisms decreases with increase of intron number in genes. The length of introns and exons in A. thaliana and O. sativa genes is change with increase of intron number in genes by high coefficient of correlation. Linear dependence between the sum of exon lengths and intron number in genes increased proportionally to number of gene introns. The average length of introns and genes of human depend on density of genes in DNA. 相似文献
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High resolution methylome map of rat indicates role of intragenic DNA methylation in identification of coding region 总被引:1,自引:0,他引:1
Sati S Tanwar VS Kumar KA Patowary A Jain V Ghosh S Ahmad S Singh M Reddy SU Chandak GR Raghunath M Sivasubbu S Chakraborty K Scaria V Sengupta S 《PloS one》2012,7(2):e31621
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R Vlasak O Wiborg K Richter S Burgschwaiger J Vuust G Kreil 《European journal of biochemistry》1987,169(1):53-58
From a genomic library of Xenopus laevis, two genes coding for different preprocaeruleins have been isolated and sequenced. These correspond to the type I and type III precursors analyzed previously at the cDNA level [Richter, K., Egger, R. and Kreil, G. (1986) J. Biol. Chem. 261, 3676-3680]. The type III gene comprises eight exons; the type I apparently contains eight exons as well, of which six have been sequenced. The genetic information for the dekapeptide caerulein is present on small exons of 45 base pairs. The two genes are highly homologous in their 5'-flanking region, the exon/intron boundaries, and long stretches of intron sequences. A possible scheme for the evolution of this small family of genes through exon and gene duplications is presented. In the type I gene, in place of one of the caerulein exons, a potential exon with conserved splice sites was discovered. If expressed in some frog cells, this exon would code for a new peptide 60% homologous to caerulein. 相似文献
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N G Markova L N Marekov C C Chipev S Q Gan W W Idler P M Steinert 《Molecular and cellular biology》1993,13(1):613-625
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Zhang K Howes KA He W Bronson JD Pettenati MJ Chen C Palczewski K Wensel TG Baehr W 《Gene》1999,240(1):23-34
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The exon-intron structure of human, insect (Drosophila sp.), and dicot plant (Arabidopsis thaliana) genes was considered. In each genome there exists a characteristic intron length. Anomalously long introns was usually the first introns in genes. In each sample there are correlations between the lengths of neighboring exons and between exon lengths and closeness to the consensus of the sites at exon boundaries. Exons and exon pairs containing an integer number of triplets are preferred. These results are relevant to the study of splicing mechanism and evolution of introns, as well as construction of gene recognition algorithms. 相似文献