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Statistics plays a crucial role in research, planning and decision-making in the health sciences. Progress in technologies and continued research in computational statistics has enabled us to implement sophisticated mathematical models within software that are handled by non-statistician researchers. As a result, over the last decades, medical journals have published a host of papers that use some novel statistical method. The aim of this paper is to present a review on how the statistical methods are being applied in the construction of scientific knowledge in health sciences, as well as, to propose some improvement actions. From the early twentieth century, there has been a remarkable surge in scientific evidence alerting on the errors that many non-statistician researchers were making in applying statistical methods. Today, several studies continue showing that a large percentage of articles published in high-impact factor journals contain errors in data analysis or interpretation of results, with the ensuing repercussions on the validity and efficiency of the research conducted. Scientific community should reflect on the causes that have led to this situation, the consequences to the advancement of scientific knowledge and the solutions to this problem.  相似文献   

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In this paper the relationship between the number of males and females in a community, between the number of boys and girls in a family, between the number of animals trapped and untrapped in an animal experiment, between the number of infected and uninfected in an epidemiological study, between the number of mutagens and non-mutagens in a given sample of toxicological experiments, and others, is studied. The general expression for the correlation coefficient, ?, is obtained when N, the community size N, has a discrete exponential family distribution recently studied by Janardan (1980). This is then specialized to some well known discrete distributions.  相似文献   

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