共查询到20条相似文献,搜索用时 37 毫秒
1.
The phytochemical investigation on Tanacetum sinaicum (Fresen.) Delile ex Bremer & Humphries led to the isolation of eight flavonoid aglycones (apigenin 1, acacetin 2, luteolin 3, chrysoeriol 4, cirsilineol 5, jaceidin 6, chrysosplenetin 7 and vitexicarpin; casticin 8), four flavonoid glycosides (apigenin 7-O-β-glucopyranoside 9, apigenin 7-O-β-glucuronide 10, luteolin 7-O-β-glucopyranoside 11 and luteolin 7-O-β-glucuronide 12) and three phenolics (4-hydroxy-3-methoxy benzoic acid 13, 3,4-dimethoxy benzoic acid 14 and 4-hydroxy acetophenone 15). Their structures were determined by chemical and spectroscopic analysis. Among them, compounds 1–3, 9, 11, 13 and 14 were reported for the first time from T. sinaicum. The chemotaxonomic significance of the isolated flavonoids was also summarized. 相似文献
2.
The phytochemical study was done on the methanol extract from of the leaves of Symphonia globulifera. This plant has been used in traditional medicine to treat of different ailments such as malaria, diseases of the skin, diabetes, cough, intestinal worms, pre-hepatic jaundice and fever. Chromatographic fractionation and purification of this extract led to the isolation and characterization of twelve compounds (1–12) including pristriol (1), robustaflavone (2), polycarpol (3), 7''-O-methylrobustaflavone (4), amentoflavone (5), stigmasterol glucoside (6), epicatechin (7), apigenin (8), luteolin (9), 1,5-dihydroxyxanthone (10), β-sitosterol 3-β-D-glucopyranoside (11) and a mixture of stigmasterol and β-sitosterol (12). The structures of compounds 1–12 were elucidated on the basis of 1D and 2D NMR, mass spectrometric and the spectroscopic data as well as comparison with the literature. All these compounds were isolated for the first time from Symphonia genus. The NMR spectra and structure elucidation of compound 1 were reported for the first in the literature. The antibacterial and antioxidant activities of three of these compounds were evaluated. The chemophenetic significance of these compounds is also discussed. 相似文献
3.
Thi Nga Vo Phi Linh Nguyen Lam Truong Tuong Phung Nguyen Vo Kim Phi Phung Nguyen Ngoc Suong Nguyen 《Phytochemistry letters》2012,5(3):673-676
A new iridoid, 5β,6β-dihydroxyantirrhide (1) was isolated from the dried leaves of Pseuderanthemum carruthersii (Seem.) Guill. var. atropurpureum (Bull.) Fosb. (Acanthaceae), together with 13 known compounds, including two iridoids, linarioside and antirrhinoside; five phenylethanoids, echipuroside A, verbascoside, isoverbascoside, isomartynoside and osmanthuside B; and six flavonoids, luteolin 7-O-β-d-glucopyranoside, luteolin 7-O-rutinoside, apigenin 7-O-rutinoside, apigenin 6-C-α-l-arabinopyranosyl–8-C-β-l-arabinopyranoside, apigenin 6,8-di-C-α-l-arabinopyranoside and apigenin 6-C-β-d-xylopyranosyl–8-C-α-l-arabinopyranoside. Their chemical structures were elucidated by 1D and 2D NMR as well as HR-ESI-MS spectroscopic analysis. Some purified compounds were evaluated the acetylcholinesterase inhibition and cytotoxic activities against the HeLa cervical cancer cell line and the MCF-7 breast cancer cell line at the concentration of 100 μg/mL. Luteolin 7-O-β-d-glucopyranoside exhibited cytotoxic activities against both the HeLa cervical cancer cell line and the MCF-7 breast cancer cell line. Verbascoside and isoverbascoside showed strong cytotoxic activity against the MCF-7 breast cancer cell line. The tested compounds showed the AChE inhibitory activity fairly weak. 相似文献
4.
From the leaves of Aphananthe aspera (Thunb.) Planch. (Family: Cannabaceae), six flavonol glycosides, such as quercetin 3-O-β-glucopyranoside (1), kaempferol 3-O-β-glucopyranoside (2), quercetin 3-O-rutinoside (3), kaempferol 3-O-rutinoside (4), quercetin 3-O-neohesperidoside (5) and kaempferol 3-O-neohesperidoside (6) were isolated and identified. Structure elucidation of these compounds was performed on the basis of NMR spectral data. All these compounds were isolated for the first time from the genus Aphananthe. Chemotaxonomic significance and distribution of these flavonoid derivatives among the genera of Cannabaceae are explained in detail. 相似文献
5.
Flavones and flavone glycosides from Halophila johnsonii 总被引:1,自引:0,他引:1
Halophila johnsonii Eiseman is a shallow-water marine angiosperm which contains UV-absorbing metabolites. Studies on methanol extracts of H. johnsonii by means of HPLC-UV, NMR, HPLC-MS resulted in isolation and identification of seven previously unknown flavone glycosides: 5,6,7,3′,4′,5′-hexahydroxyflavone-7-O-β-glucopyranoside (1), 5,6,7,3′,4′,5′-hexahydroxyflavone-7-O-(6″-O-acetyl)-β-glucopyranoside (2), 6-hydroxyluteolin-7-O-(6″-O-acetyl)-β-glucopyranoside (3), 6-hydroxyapigenin-7-O-(6″-O-acetyl)-β-glucopyranoside (4), 6-hydroxyapigenin-7-O-(6″-O-[E]-coumaroyl)-β-glucopyranoside (5), 6-hydroxyapigenin-7-O-(6″-O-[E]-caffeoyl)-β-glucopyranoside (6) and 6-hydroxyluteolin-7-O-(6″-O-[E]-coumaroyl)-β-glucopyranoside (7). Also isolated were three known flavone glycosides, 6-hydroxyluteolin 7-O-β-glucopyranoside (8), scutellarein-7-O-β-glucopyranoside (9), and spicoside (10), and five known flavones, pedalitin (11), ladanetin (12), luteolin (13), apegenin (14) and myricetin (15). Qualitative comparison of the flavonoid distribution in the leaf and rhizome-root portions of the plant was also investigated, with the aim of establishing the UV-protecting roles that flavonoids played in the sea grass. 相似文献
6.
Mohamed Omar Yosuke Matsuo Hajime Maeda Yoshinori Saito Takashi Tanaka 《Phytochemistry letters》2013,6(3):486-490
Two novel glycosides, 4,5-dimethoxy-3-hydroxyphenol 1-O-β-(6′-O-galloyl)-glucopyranoside (1) and (+)-2α-O-galloyl lyoniresinol 3α-O-β-d-xylopyranoside (2), as well as a novel ellagitannin named epiquisqualin B (3), were isolated from sapwood of Quercus mongolica var. crispula along with 19 known phenolic compounds. The structures of the novel compounds were elucidated on the basis of chemical and spectroscopic investigation. Compound 2 is the first example of a lignan galloyl ester, and 3 is the oxidation product of vescalagin, which is the major ellagitannin of this plant. 相似文献
7.
6-Prenylapigenin (1) and 8-prenylapegenin (2) were semi-synthesized from apigenin by nuclear prenylation. Morusin (3) was isolated from the root bark of Morus alba L. The microbial transformation studies of these three bioactive prenylated apigenin derivatives were performed using eighteen cell cultures in order to select microorganisms capable of transforming them. It was identified that Mucor hiemalis (KCTC 26779) showed the ability to metabolize the parent compounds (1–3) into three new (4–6) and one known (7) glucosylated derivatives with high efficiency. Their structures were established as 6-prenylapigenin 7-O-β-d-glucopyranoside (4), 8-prenylapigenin 7-O-β-d-glucopyranoside (5), morusin 5-O-β-d-glucopyranoside (6), and morusin 4′-O-β-d-glucopyranoside (7) by the spectroscopic methods. 相似文献
8.
Five C-glycosylflavone were isolated from Vaccaria hispanica (Miller) Rauschert seeds. Their NMR spectra showed separate signals because of the existence of rotational isomers, which is an unusual phenomenon. The spectroscopic data revealed that compounds 1–5 were identified as apigenin 6-C-[α-l-arabinopyranosyl-(1′′′→2′′)-β-d-glucopyranosyl]-7-O-β-d-glucopyranoside (1), apigenin 6-C-[α-l-arabinopyranosyl-(1′′′→2′′)-β-d-glucopyranosyl]-7-O-(6′′′′-O-dihydroferuloyl)-β-d-glucopyranoside (2), apigenin 6-C-β-d-glucopyranosyl-7-O-(6′′′-O-dihydroferuloyl)-β-d-glucopyranoside (3) and isovitexin-2′′-O-arabinoside (4) and saponarin (5), respectively. The structure of ‘vaccarin’ was revised to apigenin 6-C-[α-l-arabinopyranosyl-(1′′′→2′′)-β-d-glucopyranosyl]-7-O-β-d-glucopyranoside and consequently 1 should be named ‘vaccarin’. Among the isolated compounds, 2 and 3 are new and named vaccarin E and vaccarin F, respectively. 相似文献
9.
Glycosides, 3-acetyl-(?)-epicatechin 7-O-β-glucopyranoside (1), 3-acetyl-(?)-epicatechin 7-O-(6-isobutanoyloxyl)-β-glucopyranoside (2), 3-acetyl-(?)-epicatechin 7-O-[6-(2-methyl-butanoyloxyl)]-β-glucopyranoside (3), (5Z)-6-[5-(2-hydroxypropan-2-yl)-2-methyl-tetrahydrofuran-2-yl]-3-methylhexa-1,5-dien-3-O-β-glucopyranoside (4), hydroquinone O-[6-(3-hydroxyisobutanoyl)]-β-galactopyranoside (5), 4-(4-O-β-glucopyranosyl-phenoxy)-1-O-β-glucopyranosyl-1,3-benzenediol (6), 7,8-erythro-dihydroxy-3,4,5-trimethoxy-phenyl-propane8-O-β-glucopyranoside (7), 6,7-dimethylbenzofuranol 5-O-β-xylopyranosyl-(1 → 6)-β-glucopyranoside (8), along with 30 known glycosides, were isolated from Breynia fruticosa and Breynia rostrata (Euphorbiaceae). Their structures were determined on the basis of spectroscopic analysis and chemical methods. 相似文献
10.
One new derivative of ferulic acid (1), two new caffeic acid derivatives (2 and 3) and three known derivatives of caffeic acid: 6-O-(E)-caffeoyl-glucopyranose (4), (E)-caffeic acid 4-O-β-glucopyranoside (5) and 5-caffeoylquinic acid (chlorogenic acid, 6) were isolated from a butanolic fraction of extract from Telekia speciosa flowers. Moreover, the flavonol glucoside–patulitrin (7) was identified in the analyzed extract. Structures of (E)-ferulic acid 4-O-β-(6-O-2-hydroxyisovaleryl)-glucopyranoside (1), (E)-caffeic acid 4-O-β-(6-O-2-hydroxyisovaleryl)-glucopyranoside (2) and (E)-caffeic acid 4-O-β-(6-O-3-hydroxy-2-methylpropanoyl)-glucopyranoside (3) were elucidated by 1D and 2D NMR, HRESIMS and other spectral analyses. 相似文献
11.
Kamel H. Shaker Nagy Morsy Heidi Zinecker Johannes F. Imhoff Bernd Schneider 《Phytochemistry letters》2010,3(4):212-216
Three new metabolites, 5-hydroxy-3,7-dimethoxyflavone-4′-O-β-glucopyranoside (1), 2β,19-epoxy-3β,14β-dihydroxy-19-methoxy-5α-card-20(22)-enolide (4) and β-anhydroepidigitoxigenin-3β-O-glucopyranoside (5), along with two known compounds, uzarigenine (2) and β-anhydroepidigitoxigenin (3), were isolated from Calotropis procera (Asclepiadaceae). The structure elucidation was accomplished mainly by nuclear magnetic resonance (NMR) spectroscopic and mass spectrometric methods. To examine putative antimicrobial or cytotoxic activities, various bioassays were performed. Uzarigenine (2) demonstrated moderate cytotoxicity. 相似文献
12.
In this study the red flowers of Canna indica (Cannaceae) were extracted by using sonicator and isolation of anthocyanins have been carried out. Four anthocyanin pigments have been isolated apart from quercetin and lycopene. They are Cyanidin-3-O-(6′′-O-α-rhamnopyranosyl)-β-glucopyranoside (1), Cyanidin-3-O-(6′′-O-α-rhamnopyranosyl)-β-galactopyranoside (2), Cyanidin-3-O-β-glucopyranoside (3) and Cyanidin-O-β-galactopyranoside (4). These compounds were isolated by using HPLC and their structures were subsequently determined on the basis of spectroscopic analyses, i.e., 1H NMR, 13C NMR, HMQC, HMBC, ESI-MS, FTIR, UV–Visible etc. The isolated compounds showed good antioxidant activity thus makes it suitable for use in food coloration and as a nutraceutical. Thus it is a promising pigment source for food applications. 相似文献
13.
A new furan-2-carbonyl C-(6′-O-galloyl)-β-glucopyranoside (scleropentaside F, 1) and a new alkyl glucoside [butane-2,3-diol 2-(6′-O-galloyl)-O-β-glucopyranoside, 2] were isolated from the entire hemi-parasitic plant, Dendrophthoe pentandra growing on Tectona grandis together with ten known compounds including, benzyl-O-β-d-glucopyranoside (3), benzyl-O-α-l-rhamnopyranosyl-(1 → 6)-β-d-glucopyranoside (4), benzyl-O-β-d-apiofuranosyl-(1 → 6)-β-d-glucopyranoside (5), methyl gallate 3-O-β-d-glucopyranoside (6), methyl gallate 3-O-(6′-O-galloyl)-β-d-glucopyranoside (7), (+)-catechin (8), procyanidin B-1 (9) and procyanidin B-3 (10), bridelionoside A (11), and kiwiionoside (12). In addition, compounds 1, 3–9 were isolated from this species growing on the different host, Mangifera indica. The structure elucidations were based on physical data and spectroscopic evidence including 1D and 2D experiments. 相似文献
14.
Five flavonols, four flavones and one C-glycosylflavone were isolated from the leaves of Cathcartia villosa which is growing in the Himalayan Mountains. They were characterized as quercetin 3-O-vicianoside (1), quercetin 7,4′-di-O-glucoside (3), quercetin 3-O-rutinoside (4), quercetin 3-O-glucoside (5), quercetin 3-O-arabinosylarabinosylglucoside (6) (flavonols), luteolin (7), luteolin 7-O-glucoside (8), apigenin (9), chrysoeriol (10) (flavones), and vicenin-2 (11) (C-glycosylflavone) by UV, LC-MS, acid hydrolysis, NMR and/or HPLC and TLC comparisons with authentic samples. On the other hand, two flavonols 1 and kaempferol 3-O-vicianoside (2) were isolated and identified from the flowers of the species. Flavonoids were reported from the genus Cathcartia in this survey for the first time. Their chemical characters were chemotaxonomically compared with those of related Papaveraceous genera, Meconopsis and Papaver. 相似文献
15.
Céline Rivière Van Nguyen Thi Hong Luc Pieters Yvan Vander Heyden Joëlle Quetin-Leclercq 《Phytochemistry》2009,70(1):86-197
Six flavonoids including two new flavones, luteolin 7-O-(4″-O-(E)-coumaroyl)-β-glucopyranoside), chrysoeriol-7-O-(4″-O-(E)-coumaroyl)-β-glucopyranoside) and a mixture of two pairs of diastereoisomeric flavonolignans, (±)-hydnocarpin 7-O-(4″-O-(E)-coumaroyl)-β-glucopyranoside)/(±)-hydnocarpin-D 7-O-(4″-O-(E)-coumaroyl)-β-glucopyranoside) with a 2:1 ratio were isolated from the whole plant of Mallotus metcalfianus Croizat, in addition to 10 known compounds. Their structures were evaluated on the basis of different spectroscopic methods, including extensive 1D and 2D NMR spectroscopy. Some extracts have moderate antimicrobial properties and interesting antiradical (DPPH) activity, as well as some compounds isolated from this species. Tannins were also identified in some active extracts. 相似文献
16.
The major flavonoids of Marchantia polymorpha var. polymorpha and aquatica are the 7-O-β-d-glucuronides of apigenin and luteolin, luteolin 3′-O-β-d-glucuronide, luteolin 7,3′-di-O-β-d-glucuronide, and the 7,4′-di-O-β-d-glucuronides of apigenin and luteolin. These are accompanied by minor amounts of apigenin, luteolin, luteolin 3′,4′-di-O-β-d-glucuronide and luteolin 7,3′,4′-tri-O-β-d-glucuronide. All the luteolin di- and triglucuronides except the 3′,4′-di- substituted compound are new natural products. 相似文献
17.
Jyoti Srivastava 《Carbohydrate research》2010,345(14):2023-2029
Methylated anthocyanin glycosides were isolated from red Canna indica flower and identified as malvidin 3-O-(6-O-acetyl-β-d-glucopyranoside)-5-O-β-d-glucopyranoside (1), malvidin 3,5-O-β-d-diglucopyranoside (2), cyanidin-3-O-(6″-O-α-rhamnopyranosyl-β-glucopyranoside (3), cyanidin-3-O-(6″-O-α-rhamnopyranosyl)-β-galactopyranoside (4), cyanidin-3-O-β-glucopyranoside (5) and cyanidin-O-β-galactopyranoside (6) by HPLC-PDA. Their structures were subsequently determined on the basis of spectroscopic analyses, that is, 1H NMR, 13C NMR, HMQC, HMBC, ESI-MS, and UV-vis. Compounds (1-4) were found to be in major quantity while compounds (5-6) were in minor quantity. 相似文献
18.
Sesquiterpene lactones, especially guaianolides, are widespread in the genus Crepis L. We have undertaken the chemical investigation of Crepis commutata (Spreng.) Greuter, an edible plant in Crete. From the non-polar extract of the aerial flowering parts of C. commutata five sesquiterpene lactones: 8-epi-grosheimin (1), 8-epi-isoamberboin (2), 8-epi-isolipidiol (3), 3-acetyl-8-epi-isolipidiol (4), integrifolin 3-O-β-D-glucopyranoside (5), two flavonoids: luteolin (6), luteolin 7-O-β-D-glucuronide (7), and three phenolic acids: p-anisic acid (8), p-hydroxyphenylacetic acid (9) and E-caffeic acid (10) were isolated. The structures of the isolated compounds were elucidated by high-field NMR spectroscopy. 相似文献
19.
Gülcemal D Alankuş-Çalışkan O Karaalp C Ors AU Ballar P Bedir E 《Carbohydrate research》2010,345(17):2529-2533
A new flavanone glycoside, naringenin-7-O-β-d-glucuronopyranoside, and a new flavonol glycoside, 6-hydroxykaempferol-7-O-β-d-glucuronopyranoside were isolated together with 12 known compounds, 5 flavone glycoside; hispidulin-7-O-β-d-glucuronopyranoside, apigenin-7-O-β-d-methylglucuronopyranoside, hispidulin-7-O-β-d-methylglucuronopyranoside, hispidulin-7-O-β-d-glucopyranoside, apigenin-7-O-β-d-glucopyranoside, a flavonol; kaempferol, two flavone; apigenin, and luteolin, a flavanone glycoside; eriodictyol-7-O-β-d-glucuronopyranoside, and three phenol glycoside; arbutin, salidroside, and 3,5-dihydroxyphenethyl alcohol-3-O-β-d-glucopyranoside from Centaurea urvillei subsp. urvillei. The structure elucidation of the new compounds was achieved by a combination of one- (1H and 13C) and two-dimensional NMR techniques (G-COSY, G-HMQC, and G-HMBC) and LC-ESI-MS. The isolated compounds were tested for their antiproteasomal activity. The results indicated that kaempferol, a well known and widely distributed flavonoid in the plant kingdom, was the most active antiproteasomal agent, followed by apigenin, eriodictyol-7-O-β-d-glucuronopyranoside, 3,5-dihydroxyphenethyl alcohol-3-O-β-d-glucopyranoside, and salidroside, respectively. 相似文献
20.
Two phenolic acids (1 and 2) and seven flavonoids (3–9) were isolated from the aerial parts of Alyssum alyssoides (Brassicaceae). All these compounds (1–9) were isolated from this particular species for the first time. Their structures were identified, on the basis of MS and NMR spectra as: p-hydroxy-benzoic acid (1), 3-methoxy-4-hydroxybenzoic acid (vanillic acid) (2), kaempferol 3-O-β-D-glucopyranoside (astragalin) (3), kaempferol 3-O-(6″-α-L-rhamnopyranosyl)-β-D-glucopyranoside (nicotiflorin) (4), quercetin 3-O-β-D-glucopyranoside (isoquercetin) (5), quercetin 3-O-β-D-galactopyranoside (hyperoside) (6), isorhamnetin 3-O-β-D-glucopyranoside (7), isorhamnetin 3-O-β-D-galactopyranoside (8) and isorhamnetin 3-O-(6″-α-L-rhamnopyranosyl)-β-D-glucopyranoside (narcissin) (9). The chemotaxonomic significance of these compounds was summarized. 相似文献