The effect of chondroitin sulfate preparations on wound healing and the strength of the surgical scar

An experimental investigation of the ability of the chondroitinsulphate preparation produced from cattle tracheas, of rumalon and chonsuride to stimulate the regeneration of cutaneous coverings in case of their injury was carried out. A strength of the surgical cicatrix and its elongation at rupture in two weeks' injections of chondroitinsulphate increased in comparison with control. A stimulating effect of chondroitinsulphate to regeneration of flesh wound in case of local single action didn't differ essentially from the effect of chonsuride. In case of application of the preparations, an area of wound for the rats received chondroitinsulphate was already on the eighth day twice as less in comparison with the animals treated with chonsuride. Thus, a stimulating effect of chondroitinsulphate preparation to the regeneration of damaged cutaneous coverings by both parenteral and local administration was shown.     

Cutaneous zygomycosis caused by Rhizopus arrhizus in a surgical wound.

We report a case of cutaneous zygomycosis caused by Rhizopus arrhizus in a surgical wound following colostomy. The patient was a diabetic and in addition presented others risk factors. Zygomycosis was suspected when a necrotic wound surface appeared in the appropiate clinical setting. Diagnosis was confirmed on a combined histological and microbiological study. Extensive surgical resection, high doses of amphotericin B and treatment of the underlying conditions permitted the control of the infection.     

Open surgical revascularization for wound healing: past performance and future directions

The goal of lower extremity revascularization is to relieve pain, heal wounds, and prevent amputations by restoration of arterial perfusion. This necessarily brief overview will discuss the indications for vascular reconstruction and the diagnosis of peripheral arterial disease, and review of the "open" vascular procedures used for revascularization.     

防护细节管理在消毒供应中心微生物污染手术器械处理中的应用

探讨防护细节管理在消毒供应中心微生物污染手术器械处理中的应用价值。

随机选取我院做到防护细节管理的600件手术器械(A组)和未实施防护细节管理的600件手术器械(B组)作为研究对象, 对比实施防护细节管理对手术器械微生物污染的影响。比较实施前后器械无菌检验和微生物限度检验一次合格率、质量管理情况(回收、分类、清洗消毒、包装不合格情况)以及患者医院感染发生率变化情况。

A组器械无菌检验一次合格率为98.67%, B组器械其一次检验合格率为95.67%, 差异有统计学意义(χ²=9.953, P=0.001 6)。A组器械微生物限度检验一次合格率为99.33%, B组为95.17%(χ²=9.305, P=0.002 3)。A组器械回收不合格率为0.33%, B组不合格率为2.00%。A组器械分类不合格率为0.50%, B组为1.50%。A组器械清洗消毒不合格率为0.83%, 器械包装不合格率为0.33%;B组器械清洗消毒不合格率为1.83%, 手术器械包装不合格率1.33%。A组和B组器械导致的医院感染发生率分别为0.67%、1.67%。

防护细节管理在降低消毒供应中心手术器械微生物的污染, 提高管理质量以及降低医院感染发生率方面有重要价值。

     

Treatment of Bowen disease using the ultrasonic surgical aspirator.

In most cases, patients with Bowen disease lesions can be easily treated by surgical excision and direct closure; however, the ultrasonic surgical aspirator, an instrument in common use in many fields, offers a good treatment alternative with few drawbacks for patients with lesions that are large and/or located in joint areas, areas that are hard to heal, or areas that are surgically problematic such as the ears, nose, eyelids, and mucous membranes. The clinical application of the ultrasonic surgical aspirator in the treatment of Bowen disease promises considerable benefit in terms of patient comfort because removal of the lesion is easy, is noninvasive, and does not require hospitalization or result in restricted mobility. All of these factors, although benefiting patients, particularly the elderly, can also substantially lower the cost of treatment.     

Changes in the structure and antibiotic sensitivity of the wound microflora in suppurative surgical infection of the soft tissues

The results of the study on the composition, properties and antibiotic sensitivity of pathogenic microbes isolated from purulent wounds of the soft tissues of patients treated in the Institute clinic in 1977-1980 are presented. The frequency of secondary infection of the purulent wounds was estimated. During this period the percentage of gram-negative bacteria isolated from opened purulent foci increased. In some cases investigation of the time course of the purulent processes revealed new microbial strains, such as pathogenic staphylococci or opportunistic gram-negative bacteria. Sometimes replacement of the causative agent by new organisms was observed. The new strains were high- and multiple-resistant to the antibiotics.