Ichnology Picture

Ichnology Picture

All authors

Ronald K. Pickerill

https://doi.org/10.1080/10420940600739823

Published online:

26 January 2007

(See Color Plate V)     

2.

Gemcitabine analogues with 4-N-alkyl chain modified with fluoromethyl ketone group     

Cesar Gonzalez  Maria de Cabrera 《Nucleosides, nucleotides & nucleic acids》2018,37(4):248-260

     

3.

Disquisition on the interaction of ibuprofen–Zn(II) complex with calf thymus DNA by spectroscopic techniques and the use of Hoechst 33258 and Methylene blue dyes as spectral probes     

Nahid Shahabadi  Farshad Shiri  Mohammadsaleh Norouzibazaz  Aliyar Falah 《Nucleosides, nucleotides & nucleic acids》2018,37(3):125-146

     

4.

An efficient and practical synthesis of formylglycinamide ribonucleotide (FGAR)     

Xiu-An Zheng  Rui Wang  Rui Kong  Rong Liu 《Nucleosides, nucleotides & nucleic acids》2018,37(2):79-88

     

5.

Both enantiomers of 6′-Isoneplanocin     

Chong Liu  Qi Chen 《Nucleosides, nucleotides & nucleic acids》2017,36(10):631-636

     

6.

Synthesis of novel 3′-azido-3′-deoxy-α-L-ribo configured nucleosides: A comparative study between chemical and chemo-enzymatic methodologies     

Neha Rana  Manish Kumar  Ankita Singh  Jyotirmoy Maity  Poonam Shukla 《Nucleosides, nucleotides & nucleic acids》2018,37(4):217-231

     

7.

New and One Pot Chemoselective Synthesis of Nucleoside 5′-H-Phosphonate Diesters     

Xin Guo  Peng Jiang  Hua Fu  Yuyang Jiang  Yufen Zhao 《Nucleosides, nucleotides & nucleic acids》2013,32(9):1325-1331

     

8.

Process Research on the Preparation of DMT Protected 2′-O-Methoxyethylguanosine for Oligonucleotide Synthesis in Therapeutic Applications     

Shabbir Ali S. Taj  S. Narayanan  S. Suman Meenakshi  Yogesh S. Sanghvi  Bruce S. Ross  Vasulinga T. Ravikumar 《Nucleosides, nucleotides & nucleic acids》2013,32(9):1024-1033

     

9.

The Synthesis of [(β‐d‐Ribofuranosyloxy)‐methyl]nucleosides     

《Nucleosides, nucleotides & nucleic acids》2013,32(4):655-669

     

10.

Synthesis of 3′-Amino-3′-Deoxyguanosine and 3′-Amino-3′-Deoxyxyloguanosine Monophosphate Hepdirect Prodrugs from Guanosine     

Brett C. Bookser  Nicholas B. Raffaele  K. Raja Reddy  Kevin Fan  Wenjian Huang  Mark D. Erion 《Nucleosides, nucleotides & nucleic acids》2013,32(10):969-986

     

11.

A Highly Efficient and Selective Synthesis of 1,2,3-Triazole Linked Saccharide Nucleosides Via “Click Chemistry”     

Haixin Ding  Ruchun Yang  Yang Song  Qiang Xiao  Jun Wu 《Nucleosides, nucleotides & nucleic acids》2013,32(4):368-375

     

12.

PHENYLALKYL BACKBONE MODIFIED OLIGODEOXYNUCLEOTIDES,THEIR SYNTHESIS AND THE INFLUENCE OF THE ALKYL CHAIN LENGTH     

《Nucleosides, nucleotides & nucleic acids》2013,32(4-7):1275-1278

Phenylalkyl modified phosphoramidites (alkyl chain length n = 1,2,3,5; Fig. 1) were synthesised and incorporated into a DNA hexamer (5′-d(GCCp-GCG); p = place of modification). The obtained diastereomeres were separated by RP-HPLC. After hybridisation with the complementary DNA strand T_m-value and thermodynamic data were measured. The stability of duplexes depends on the linker length and the absolute configuration of the backbone modified oligodeoxynucleotides (Rp, Sp).

PHENYLALKYL BACKBONE MODIFIED OLIGODEOXYNUCLEOTIDES, THEIR SYNTHESIS AND THE INFLUENCE OF THE ALKYL CHAIN LENGTH

All authors

Stefan Amberg & Joachim W. Engels

https://doi.org/10.1081/NCN-100002535

Published online:

07 February 2007

Figure 1. Structure of Rp- and Sp-configurated oligomers; synthesised phosphoramidites.     

13.

Synthesis and Evaluation of RNA Transesterification Efficiency Using Stereospecific Serinol-Terpyridine Conjugates     

William C. Putnam  James K. Bashkin 《Nucleosides, nucleotides & nucleic acids》2013,32(9):1309-1323

     

14.

Side‐Chain Conformational Restriction in Template‐Competitive Inhibitors of E. coliDNA Polymerase I Klenow Fragment: Synthesis,Structural Characterization and Inhibition Activity     

《Nucleosides, nucleotides & nucleic acids》2013,32(11):1751-1765

     

15.

1H and 13C NMR Chemical Shifts of Methacrylate Molecules Associated with DMPC and/or DPPC Liposomes     

Seiichiro Fujisawa  Mariko Ishihara  Yoshinori Kadoma 《Journal of liposome research》2013,23(3-4):167-174

     

16.

NEST AND EGGS OF THE PINC-PINC (OR TINK-TINK) GRASS WARBLER,CISTICOLA TEXTRIX TEXTRIX (Vieill.)     

Major R. C. Bolster M.B.O.U  P. R. Robertson 《Ostrich》2013,84(1):20-26

     

17.

Synthesis of Triazole Nucleoside Derivatives     

《Nucleosides, nucleotides & nucleic acids》2013,32(4):419-435

Abstract

5′-O-Mesyl-2′,3′-O-isopropylidene ribonucleosides (4 and 12) were converted to their 5′-substituted nucleosides in good yields by reacted with NaN₃ or KI. 2′,3′-O-Isopropylidene ribonucleosides (3 and 11) were prepared in good yields from ribonucleosides 1 and 2 with a reaction mixture of acetone and triethyl orthoformate instead of using acetone diethyl acetal. Compound 1 or 2 was treated with 2-acetoxyisobutyryl halide (Cl or Br) to give 1-[2-O-acetyl-3-halo-3-deoxy-5-O-(2,5,5-trimethyl-1,3-dioxolan-4-on-2-yl)-β-D-xylofuranosyl]-1,2,4-triazole-3-carboxamide (19, 22, and 23) in high yields. Instead of using 2-acetoxyisobutyryl bromide, the mixture of 2-acetoxyisobutyryl chloride and NaBr was employed in the synthesis of 22 and 23. Treatment of 19 with an activated Zn/Cu couple and deprotection gave 2′,3′-anhydro nucleoside (21), and treatment of 22 and 23 with an activated Zn/Cu couple and a little of HOAc and deprotection gave corresponding 2′,3′-unsaturated triazole nucleosides (24 and 25), respectively. The biological activity of the compounds (7 ～ 10, 15 ～ 18, and 24) was examined in human liver cancer cells (A-549), lung cancer cells (BEL-7402), and Flu-A cells.

Synthesis of Triazole Nucleoside Derivatives

All authors

Zicheng Li, Shuhua Chen, Ning Jiang & Gang Cui

https://doi.org/10.1081/NCN-120022032

Published online:

07 February 2007

Compound 1.     

18.

D-Arbinose-Based Synthesis of homo-C-d4T and homo-C-thymidine     

Bogdan Doboszewski 《Nucleosides, nucleotides & nucleic acids》2013,32(10):875-901

     

19.

Properties of Gibberellin-binding Proteins from Normal and Dwarf-8 (A Dominant Gibberellin Non-responding Dwarf Mutant) Seedlings of Zea mays L.     

《Bioscience, biotechnology, and biochemistry》2013,77(7):1340-1342

     

20.

A Novel Synthesis of Antiviral Nucleoside Phosphoramidate and Thiophosphoramidate Prodrugs via Nucleoside H-Phosphonamidates     

Qi Sun  Xingjian Li  Shanshan Gong  Gang Liu  Liang Shen  Liang Peng 《Nucleosides, nucleotides & nucleic acids》2013,32(11):617-638

     

PHENYLALKYL BACKBONE MODIFIED OLIGODEOXYNUCLEOTIDES,THEIR SYNTHESIS AND THE INFLUENCE OF THE ALKYL CHAIN LENGTH

Phenylalkyl modified phosphoramidites (alkyl chain length n = 1,2,3,5; Fig. 1) were synthesised and incorporated into a DNA hexamer (5′-d(GCCp-GCG); p = place of modification). The obtained diastereomeres were separated by RP-HPLC. After hybridisation with the complementary DNA strand T_m-value and thermodynamic data were measured. The stability of duplexes depends on the linker length and the absolute configuration of the backbone modified oligodeoxynucleotides (Rp, Sp).

PHENYLALKYL BACKBONE MODIFIED OLIGODEOXYNUCLEOTIDES, THEIR SYNTHESIS AND THE INFLUENCE OF THE ALKYL CHAIN LENGTH

All authors

Stefan Amberg & Joachim W. Engels

https://doi.org/10.1081/NCN-100002535

Published online:

07 February 2007

Figure 1. Structure of Rp- and Sp-configurated oligomers; synthesised phosphoramidites.     

13.

Synthesis and Evaluation of RNA Transesterification Efficiency Using Stereospecific Serinol-Terpyridine Conjugates     

William C. Putnam  James K. Bashkin 《Nucleosides, nucleotides & nucleic acids》2013,32(9):1309-1323

     

14.

Side‐Chain Conformational Restriction in Template‐Competitive Inhibitors of E. coliDNA Polymerase I Klenow Fragment: Synthesis,Structural Characterization and Inhibition Activity     

《Nucleosides, nucleotides & nucleic acids》2013,32(11):1751-1765

     

15.

1H and 13C NMR Chemical Shifts of Methacrylate Molecules Associated with DMPC and/or DPPC Liposomes     

Seiichiro Fujisawa  Mariko Ishihara  Yoshinori Kadoma 《Journal of liposome research》2013,23(3-4):167-174

     

16.

NEST AND EGGS OF THE PINC-PINC (OR TINK-TINK) GRASS WARBLER,CISTICOLA TEXTRIX TEXTRIX (Vieill.)     

Major R. C. Bolster M.B.O.U  P. R. Robertson 《Ostrich》2013,84(1):20-26

     

17.

Synthesis of Triazole Nucleoside Derivatives     

《Nucleosides, nucleotides & nucleic acids》2013,32(4):419-435

Abstract

5′-O-Mesyl-2′,3′-O-isopropylidene ribonucleosides (4 and 12) were converted to their 5′-substituted nucleosides in good yields by reacted with NaN₃ or KI. 2′,3′-O-Isopropylidene ribonucleosides (3 and 11) were prepared in good yields from ribonucleosides 1 and 2 with a reaction mixture of acetone and triethyl orthoformate instead of using acetone diethyl acetal. Compound 1 or 2 was treated with 2-acetoxyisobutyryl halide (Cl or Br) to give 1-[2-O-acetyl-3-halo-3-deoxy-5-O-(2,5,5-trimethyl-1,3-dioxolan-4-on-2-yl)-β-D-xylofuranosyl]-1,2,4-triazole-3-carboxamide (19, 22, and 23) in high yields. Instead of using 2-acetoxyisobutyryl bromide, the mixture of 2-acetoxyisobutyryl chloride and NaBr was employed in the synthesis of 22 and 23. Treatment of 19 with an activated Zn/Cu couple and deprotection gave 2′,3′-anhydro nucleoside (21), and treatment of 22 and 23 with an activated Zn/Cu couple and a little of HOAc and deprotection gave corresponding 2′,3′-unsaturated triazole nucleosides (24 and 25), respectively. The biological activity of the compounds (7 ～ 10, 15 ～ 18, and 24) was examined in human liver cancer cells (A-549), lung cancer cells (BEL-7402), and Flu-A cells.

Synthesis of Triazole Nucleoside Derivatives

All authors

Zicheng Li, Shuhua Chen, Ning Jiang & Gang Cui

https://doi.org/10.1081/NCN-120022032

Published online:

07 February 2007

Compound 1.     

18.

D-Arbinose-Based Synthesis of homo-C-d4T and homo-C-thymidine     

Bogdan Doboszewski 《Nucleosides, nucleotides & nucleic acids》2013,32(10):875-901

     

19.

Properties of Gibberellin-binding Proteins from Normal and Dwarf-8 (A Dominant Gibberellin Non-responding Dwarf Mutant) Seedlings of Zea mays L.     

《Bioscience, biotechnology, and biochemistry》2013,77(7):1340-1342

     

20.

A Novel Synthesis of Antiviral Nucleoside Phosphoramidate and Thiophosphoramidate Prodrugs via Nucleoside H-Phosphonamidates     

Qi Sun  Xingjian Li  Shanshan Gong  Gang Liu  Liang Shen  Liang Peng 《Nucleosides, nucleotides & nucleic acids》2013,32(11):617-638

     

Synthesis of Triazole Nucleoside Derivatives

Abstract

5′-O-Mesyl-2′,3′-O-isopropylidene ribonucleosides (4 and 12) were converted to their 5′-substituted nucleosides in good yields by reacted with NaN₃ or KI. 2′,3′-O-Isopropylidene ribonucleosides (3 and 11) were prepared in good yields from ribonucleosides 1 and 2 with a reaction mixture of acetone and triethyl orthoformate instead of using acetone diethyl acetal. Compound 1 or 2 was treated with 2-acetoxyisobutyryl halide (Cl or Br) to give 1-[2-O-acetyl-3-halo-3-deoxy-5-O-(2,5,5-trimethyl-1,3-dioxolan-4-on-2-yl)-β-D-xylofuranosyl]-1,2,4-triazole-3-carboxamide (19, 22, and 23) in high yields. Instead of using 2-acetoxyisobutyryl bromide, the mixture of 2-acetoxyisobutyryl chloride and NaBr was employed in the synthesis of 22 and 23. Treatment of 19 with an activated Zn/Cu couple and deprotection gave 2′,3′-anhydro nucleoside (21), and treatment of 22 and 23 with an activated Zn/Cu couple and a little of HOAc and deprotection gave corresponding 2′,3′-unsaturated triazole nucleosides (24 and 25), respectively. The biological activity of the compounds (7 ～ 10, 15 ～ 18, and 24) was examined in human liver cancer cells (A-549), lung cancer cells (BEL-7402), and Flu-A cells.

Synthesis of Triazole Nucleoside Derivatives

All authors

Zicheng Li, Shuhua Chen, Ning Jiang & Gang Cui

https://doi.org/10.1081/NCN-120022032

Published online:

07 February 2007

Compound 1.     

18.

D-Arbinose-Based Synthesis of homo-C-d4T and homo-C-thymidine     

Bogdan Doboszewski 《Nucleosides, nucleotides & nucleic acids》2013,32(10):875-901

     

19.

Properties of Gibberellin-binding Proteins from Normal and Dwarf-8 (A Dominant Gibberellin Non-responding Dwarf Mutant) Seedlings of Zea mays L.     

《Bioscience, biotechnology, and biochemistry》2013,77(7):1340-1342

     

20.

A Novel Synthesis of Antiviral Nucleoside Phosphoramidate and Thiophosphoramidate Prodrugs via Nucleoside H-Phosphonamidates     

Qi Sun  Xingjian Li  Shanshan Gong  Gang Liu  Liang Shen  Liang Peng 《Nucleosides, nucleotides & nucleic acids》2013,32(11):617-638