云南省宏痣泥蜂属二新种（膜翅目：泥蜂科）

本文记述采自云南省的宏痣泥蜂属２新种：皱胸宏痣泥蜂Ｓｐｉｌｏｍｅｎａ ｒｈｙｔｉｔｈｏｒａｃｉｃａ,ｓｐ．ｎｏｖ．和突唇宏痣泥蜂Ｓｐｉｌｏｍｅｎａ ｃｈｙｐｅｉ,ｓｐ．ｎｏｖ．。模式标本保存在浙江农业大学昆虫标本室。     

中国切方头泥蜂属一新种记述(膜翅目:方头泥蜂科)

记述中国广西方头泥蜂科Crabronidae切方头泥蜂属Ectemnius 1新种:漫黄切方头泥蜂Ectemnius anomalifulvus, sp. nov..模式标本保存于云南农业大学昆虫标本室.     

缨角泥蜂亚属二新种记述（膜翅目：泥蜂科）

蒙古缨角泥蜂Crossocerus (Crossocerus) neimongolensis sp. Nov.和无齿缨角泥蜂 C. (C.) exdentatus sp. Nov.。模式标本分别保存在中国科学院动物研究所昆虫标本馆和中国农业大学昆虫标本室。     

中国节腹泥蜂属一新种记述(膜翅目:方头泥蜂科)

记述采自中国海南省的方头泥蜂科Crabronniae、大头泥蜂亚科Philanthinae、节腹泥蜂属Cerceris 1新种:褐节腹泥蜂Cerceris rubigina,sp.nov..模式标本保存在云南农业大学昆虫标本室.     

缨角泥蜂亚属二新种记述 （膜翅目：泥蜂科）

 蒙古缨角泥蜂Crossocerus (Crossocerus) neimongolensis sp. Nov.和无齿缨角泥蜂 C. (C.) exdentatus sp. Nov.。模式标本分别保存在中国科学院动物研究所昆虫标本 馆和中国农业大学昆虫标本室。     

中国刺胸泥蜂属一新种记述(膜翅目:方头泥蜂科)

记述采自我国西藏自治区的方头泥蜂科方头泥蜂亚科刺胸泥蜂属1新种:黑鳞刺胸泥蜂Oxybelus nigrilamellatus,sp.nov.。模式标本保存在云南农业大学昆虫标本室。     

贵州宏痣泥蜂属一新种(膜翅目:泥蜂科)

记述了采自贵州梵净山的宏痣泥蜂属１新种：褐宏痣泥蜂。模式标本保存在浙江农业大学昆虫标本室。     

中国方头泥蜂科一新记录属附记一新种(膜翅目)

记述方头泥蜂科Crabronidae中国1新记录属:阳完眼泥蜂属Solierella Spinola,1851,并记述了1新种:金足阳完眼泥蜂Solierella cerinusipedalis,sp.nov.。模式标本保存在云南农业大学昆虫标本室。     

中国广西省节腹泥蜂属一新种记述（膜翅目：方头泥蜂科）

记述采自中国广西的方头泥蜂科Crabronidae、大头泥蜂亚科Philanthinae、节腹泥蜂属Cerceris 1新种:滑腹节腹泥蜂Cerceris abdominiglabra sp.nov.,列出了中国1新纪录种:小齿节腹泥蜂C.odontophora Schletterer。编制了吉丁节腹泥蜂组Cerceris bupresticida Group中国已知种类检索表。新种模式标本保存在浙江大学寄生蜂标本室。     

中国毛足泥蜂亚属二新种（膜翅目：泥蜂科）

记述我国缨角泥蜂属毛足泥蜂亚属2新种：单齿缨角泥蜂Crossocerus(Ble-pharipus)unidentatus sp.nov.和西藏缨角泥蜂Crossocerus(Ble-pharipus)xizangensis sp.nov.。模式标本分别保存在中国科学院动物研究所昆虫标本馆和浙江大学农学院昆虫标本室。     

A homozygous female hemophilia A

BACKGROUND:

Hemophilia A (HA), being an X-linked recessive disorder, females are rarely affected, although they can be carriers.

AIMS:

To study the mutation in F8 gene in an extended family with a homozygous female HA.

MATERIALS AND METHODS:

All the seven affected members (six males and one female) were initially screened by Conformation Sensitive Gel Electrophoresis (CSGE) and direct DNA sequencing.

RESULTS:

A homozygous missense mutation c.1315G>A (p.Gly420Ser) was identified in exon 9 of F8 gene in homozygous state in the affected female born of 1° consanguinous marriage and in all the affected male members of the family. Her factor VIII levels was found to be 5.5%, vWF:Ag 120%.

CONCLUSION:

In India, as consanguineous marriages are very common in certain communities (up to 30%), the likelihood of encountering female hemophilia is higher, although this is the first case of HA out of 1600 hemophilia families registered in our Comprehensive Haemophilia Care Center. Genetic diagnosis in such cases is not necessary as all the male children will be affected and daughters obligatory carriers.     

A glucoside of urospermal A

The aerial parts of Urospermum picroides afforded, in addition to urospermal A a p-hydroxylphenyl acetate of a glucoside of urospermal A.     

Quadruplexes of human telomere DNA analogs designed to contain G:A:G:A,G:G:A:A,and A:A:A:A tetrads

Replacement of two to four guanines by adenines in the human telomere DNA repeat dG₃(TTAG₃)₃ did not hinder the formation of quadruplexes if the substitutions took place in the terminal tetrad bridged by the diagonal loop of the intramolecular antiparallel three‐tetrad scaffold, as proved by CD and PAGE in both Na⁺ and K⁺ solutions. Thermodynamic data showed that, in Na⁺ solution, the dG₃(TTAG₃)₃ quadruplex was destabilized, the least by the two G:A:G:A tetrads, the most by the G:G:A:A tetrad in which the adenosines replaced syn‐guanosines. In physiological K⁺ solution, the highest destabilization was caused by the 4A tetrad. In K⁺, only the unmodified dG₃(TTAG₃)₃ quadruplex rearranged into a K⁺‐dependent quadruplex form, none of the multiple adenine‐modified structures did so. This may imply biological consequences for nonrepaired A‐for‐G mutations. © 2010 Wiley Periodicals, Inc. Biopolymers 93: 880–886, 2010.     

Aminopeptidase A is angiotensinase A

Summary Quantitative histochemical measurements of aminopeptidase A (APA; E.C.3.4.11.7) were done kinetically in the kidney glomeruli of rat and mouse with an instrumental setup consisting of a microdensitometer and a computer-supported morphometric system. The histochemical demonstration of APA was carried out using the simultaneous azo coupling technique (purest-grade Fast Blue B as coupling agent and -l-glutamic acid-4-methoxy-2-naphthylamide as substrate). The methodological studies show that APA activity is calcium-ion-dependent and increases linearly with the thickness of the tissue section (3–12 m) and that the time-course of APA activity as determined by linear regression is linear only for the first 1 to 2 min of the reaction. — Kinetic measurements indicate a 40% decrease in APA activities when -l-glutamic acid-4-methoxy-2-naphthylamide (-l-Glu-MNA) is replaced by -l-aspartic acid-4-methoxy-2-naphthylamide. When -l-Glu-MNA is replaced with l-alanine-4-methoxy-2-naphthylamide, which is a substrate of aminopeptidase M (APM) only very low reaction rates are measurable (about 1.4% of those with -l-Glu-MNA). 100 and 130 mM NaCl in the incubation medium increase APA activities by approximately 16%–17%. — To clarify the functional importance of APA in the kidney, their activities were measured under the influence of angiotensins. The glomerulus was selected as the measuring site, for besides APA it contains no APM or other peptidases that could degrade angiotensins (the glomerular dipeptidyl peptidase IV is not inhibited by angiotensin II). Using the Lineweaver-Burk plot, we determined a K _m of 0.16 mM for the APA in rat glomeruli and 0.14 mM in mouse glomeruli. The V _max in mouse glomeruli is 1.6 times higher than in rat glomeruli. Ang iotensin I, II and III competitively inhibit APA in the rat and mouse glomeruli. — With quantitative histochemical techniques it was possible to show that APA is equivalent to angiotensinase A (splitting off the N-terminal aspartic acid from angiotensin I and II).Supported by the Deutsche Forschungsgemeinschaft (SFB 105)     

关于一个“基细胞”的疑问

有或没有基细胞是毛鞘藻属(Bulbochaets)与枝鞘藻属(Oedocladium)的区别之一。这里叙述了Mrozinska在其专著(1985)中,将Oedocladium indicum Kama附图(即模式图)上的一个基细胞错误地移置到Oe.PrescottiiIslam上去的情况。     

关于一个"基细胞"的疑问

有或没有基细胞是毛鞘藻属与枝鞘藻属的区别之一。这里叙述了Ｍｒｏｚｉｎｓｋａ在其专著中,将Ｏｅｄｏｃｌａｄｉｕｍ ｉｎｄｉｃｕｍ Ｋａｍａｔ附图（即模式图）上的一个基细胞错误地移置到Ｏｅ．ｐｒｅｓｃｏｔｔｉｉ Ｉｓｌａｍ上去的情况。