共查询到20条相似文献,搜索用时 31 毫秒
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Andrea C. Rinaldi 《Biometals》2000,13(1):9-13
In this brief paper, the author reports on a meeting on copper research (2nd International Meeting on Copper Homeostasis and its Disorders: Molecular and Cellular Aspects) recently held in Ravello, Italy (17–21 September 1999). Aimed at elucidating the diverse roles played by copper ions in biology and medicine, as they are currently intensely investigated worldwide, the meeting has been organized around a number of major topics from prominent areas of copper research. These included the molecular and cellular basis of copper transport, molecular advances in Menkes and Wilson's diseases, the involvement of copper in neurodegenerative diseases, the structure and function of copper metalloproteins. 相似文献
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Müllerianosis is a term used to indicate lesions composed of an admixture of two or three types of müllerian-derivation glands in heterotopic sites. In this report we describe a case of spinal cord müllerianosis which occurred in a 42-year-old woman. The patient had suffered from catamenial lumbago and sciatica of three years duration before undergoing laminectomy of L2-L3 with excision of a polypoid mass that compressed nerve trunks. At histological examination, the lesion was composed of endocervical, endometrial and tubal glands within a smooth muscle nodule. These features were consistent with a diagnosis of müllerianosis. This is a very uncommon form of presentation of müllerianosis that must be correctly identified since patients can benefit from hormonal therapy. 相似文献
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Background
Vestibular schwannoma (acoustic neuroma) most commonly presents with ipsilateral disturbances of acoustic, vestibular, trigeminal and facial nerves. Presentation of vestibular schwannoma with contralateral facial pain is quite uncommon. 相似文献11.
The majority of people have back pain at some point in their lives and most are cured without any intervention. However, some patients develop chronic back pain and persistent disability. There is strong evidence that psychological factors significantly correlate with the development of chronic back pain. Back pain has also emerged as the strongest predictor of major depression. Assessing and treating patients in a manner that integrates psychosocial and biological aspects of care is the essence of excellent family medicine. This case illustrates the importance for primary care physicians of screening for depression and other psychosocial factors in assessing patients with persistent back pain. 相似文献
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Background
Sebaceous lymphadenoma is a rare benign salivary gland tumour of uncertain histogenesis. So is synchronous occurrence of two benign or malignant neoplasms. 相似文献13.
?ukasz Michalecki Dorota Gabry? Roland Kulik Jerzy Wydmański Krystyna Trela 《Reports of Practical Oncology and Radiotherapy》2011,16(5):198-201
Background
Avascular necrosis (AVN) refers to the death of osteocytes and osteoblasts. Sites such as the femoral head, the head of the humerus and the mandibula with restricted access to local blood supply are particularly vulnerable to osteonecrosis.A combination of several factors is responsible for ischaemia and is associated with AVN: corticosteroids, alcohol abuse, Cushing''s syndrome, SLE, systemic vasculitis, RA, scleroderma, haemoglobinopathies, radiotherapy. Management is based on proper diagnosis and treatment – conservative, pharmacological or surgical.Radiotherapy has become an integral part of the therapeutic programme of cancer patients. However, early and late after-effects of irradiation still constitute a significant issue in clinical practice.Aim
The aim of this report is to present two cases of acetabular protrusion and femoral head deformities after a therapeutic pelvic irradiation and draw physicians’ attention to that clinical problem which continues to be underestimated.Materials and methods
This report documents two cases of acetabular protrusion and femoral head deformities after a therapeutic pelvic radiation.Results
Avascular necrosis (AVN) constitutes a severe and challenging long-term complication in radiation oncology.Conclusion
It is necessary to take into account bone structures among organ at risk (OAR) involved in irradiation fields. The detailed analysis of the dose distribution and the use of collimators allow to decrease the total dose to OAR.An adequate management, early diagnosis and prompt, proper treatment may protect patients from long-term morbidities. 相似文献14.
A case of deep dermatophytosis in the gluteal region in a male patient successfully treated with terbinafine is described
with its clinical, mycological and histopathological features.
This revised version was published online in June 2006 with corrections to the Cover Date. 相似文献
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Arab A Karimipoor M Rajabi A Hamid M Arjmandi S Zeinali S 《Molecular biology reports》2011,38(7):4321-4326
Thalassemia intermedia is a clinical definition applied to patients whose clinical phenotype is milder than thalassemia major.
To characterize different common mechanisms involving in pathogenesis of moderate to severe β-thalassemia intermedia, we have
studied four factors in 38 Iranian patients with thalassemia intermedia: β-globin gene mutation, deletion in α-globin genes,
presence of XmnI polymprphism and RFLP haplotype at β-globin gene cluster. The results showed that 84.4% of patients were associated with
severe mutations in β-globin gene, mainly IVSII-1(G to A) (56.4%). The positive XmnI polymorphism was seen in 76.9% of the studied alleles which showed strong linkage to β° mutations and high level of fetal
hemoglobin. Co-existence of α-globin gene deletions, β+ mutation and the most frequent of RFLP haplotype (−/−, +/+, −/+, +/+, +/+, +/+, −/−) were seen in 7.7, 12.8 and 17.9%, respectively.
In this group of our study it seems the main ameliorating factor in the patients was co-inheritance of a positive XmnI polymorphism with β° mutation especially IVSII-1, which were associated with increased production of fetal hemoglobin. However,
the other probable genetic factors should be investigated to describe genotype-phenotype correlation in thalassemia intermedia
patients. 相似文献
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Glasnović M Bosnjak I Vcev A Soldo I Horvatić E Bedeković D Marjanović K Hecimović V Soldo A 《Collegium antropologicum》2008,32(1):315-318
We present a case of 77 years old male with suspected giant cell arteritis. With anamnesis, physical examination, immunological tests, Colour Doppler ultrasonography of superficial temporal artery and finally with patohistological analysis of temporal artery biopsy, we came to right diagnosis. 相似文献
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Mohamed Ali Essid Abderrazak Bouzouita Ahlem Blel Maroua Gharbi Marouen Chakroun Aycha Ben Miled Haroun Ayed Mohamed Cherif Mohamed Riadh Ben Slama Amine Derouiche Mohamed Chebil 《Journal of medical case reports》2018,12(1):376