CARM1 regulates replication fork speed and stress response by stimulating PARP1

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DNA-PKcs promotes fork reversal and chemoresistance

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Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks

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Parental histone distribution and location of the replication obstacle at nascent strands control homologous recombination

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Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells

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PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells

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POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps

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CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis

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ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms

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Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency

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Single-strand DNA breaks cause replisome disassembly

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RADX controls RAD51 filament dynamics to regulate replication fork stability

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RAD51 protects human cells from transcription-replication conflicts

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Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops

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RNA:DNA hybrids from Okazaki fragments contribute to establish the Ku-mediated barrier to replication-fork degradation

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Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming

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Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis

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Tunability of DNA Polymerase Stability during Eukaryotic DNA Replication

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EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart

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Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse

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