Lymph Node Stromal Cells Generate Antigen-Specific Regulatory T Cells and Control Autoreactive T and B Cell Responses

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Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration

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Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5

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Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs

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DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development

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Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption

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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

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Synthetic regulatory genomics uncovers enhancer context dependence at the Sox2 locus

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Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease

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Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow

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Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop

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Genome-wide aggregated trans-effects on risk of type 1 diabetes: A test of the “omnigenic” sparse effector hypothesis of complex trait genetics

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High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae

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Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells

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Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding

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Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis

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Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs

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Heterogeneity of glial progenitor cells during the neurogenesis-to-gliogenesis switch in the developing human cerebral cortex

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Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes

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