Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer

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A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53

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Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis

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Creatine promotes cancer metastasis through activation of Smad2/3

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Spatial and clonality-resolved 3D cancer genome alterations reveal enhancer-hijacking as a potential prognostic marker for colorectal cancer

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DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype

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3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain

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ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis

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Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells

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SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt

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Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins

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Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape

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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination

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Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer

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Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization

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Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation

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CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones

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IFNγ-induced stem-like state of cancer cells as a driver of metastatic progression following immunotherapy

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A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling

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Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis,transitions between metabolic states,and their regulatory mechanisms

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