Structural insights into DarT toxin neutralization by cognate DarG antitoxin: ssDNA mimicry by DarG C-terminal domain keeps the DarT toxin inhibited

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Strand-specific ChIP-seq at DNA breaks distinguishes ssDNA versus dsDNA binding and refutes single-stranded nucleosomes

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Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions

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Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M

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Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens

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A DddA ortholog-based and transactivator-assisted nuclear and mitochondrial cytosine base editors with expanded target compatibility

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Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase

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DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair

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RADX controls RAD51 filament dynamics to regulate replication fork stability

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A replication fork determinant for the establishment of sister chromatid cohesion

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Distribution and phasing of sequence motifs that facilitate CRISPR adaptation

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A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization

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Molecular basis for the reversible ADP-ribosylation of guanosine bases

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RADX prevents genome instability by confining replication fork reversal to stalled forks

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Ligation of newly replicated DNA controls the timing of DNA mismatch repair

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Crossover Position Drives Chromosome Remodeling for Accurate Meiotic Chromosome Segregation

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The vulnerable versatility of Salmonella antibiotic persisters during infection

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The FANCJ helicase unfolds DNA-protein crosslinks to promote their repair

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Proteomic profiling reveals distinct phases to the restoration of chromatin following DNA replication

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MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends

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