Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells

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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion

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Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses

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Large-scale multiplexed mosaic CRISPR perturbation in the whole organism

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Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope

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Enhanced safety and efficacy of protease-regulated CAR-T cell receptors

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CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence

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A unified atlas of CD8 T cell dysfunctional states in cancer and infection

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The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function

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An NK-like CAR T cell transition in CAR T cell dysfunction

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Oncogene-dependent sloppiness in mRNA translation

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A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

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Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

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Integrated analysis of multimodal single-cell data

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Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes

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In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions

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Human Fc Receptor-like 3 Inhibits Regulatory T Cell Function and Binds Secretory IgA

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The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function

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PD-1highCXCR5–CD4+ peripheral helper T cells promote CXCR3+ plasmablasts in human acute viral infection

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A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2

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