Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome

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Pulsatile MAPK Signaling Modulates p53 Activity to Control Cell Fate Decisions at the G2 Checkpoint for DNA Damage

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Homeostatic Control of Meiotic Prophase Checkpoint Function by Pch2 and Hop1

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The Phosphatase PP1 Promotes Mitotic Slippage through Mad3 Dephosphorylation

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Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability

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TopBP1 assembles nuclear condensates to switch on ATR signaling

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Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse

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The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition

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Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress

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Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes

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Structural insights into DarT toxin neutralization by cognate DarG antitoxin: ssDNA mimicry by DarG C-terminal domain keeps the DarT toxin inhibited

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Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma

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m6A RNA methylation regulates promoter- proximal pausing of RNA polymerase II

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Strand-specific ChIP-seq at DNA breaks distinguishes ssDNA versus dsDNA binding and refutes single-stranded nucleosomes

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Bacterial developmental checkpoint that directly monitors cell surface morphogenesis

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Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M

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Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification on biology

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DENND2B activates Rab35 at the intercellular bridge,regulating cytokinetic abscission and tetraploidy

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Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer

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Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

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