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This article proposes a new reading of early-19th-century modernity by examining India's so-called “ethnographic” paintings, and arguing that rather than participate in a trajectory of speed and acceleration these works produce colonial polyrhythmic temporality. First, the article establishes that many of these images depict action, not ethnicity or occupational group. It then situates these images in economies of circulation, viewing, politics and commercial enterprise. By focusing on the action in the subject matter—do-ing rather than do-er, processes rather than occupations—a layered, polyrhythmic range of temporalities emerges, upturning dualistic, acceleration-driven, and rupture-based understandings of visual culture from this period.  相似文献   

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Background

There has been substantial research on psychosocial and health care determinants of health disparities in the United States (US) but less on the role of modifiable risk factors. We estimated the effects of smoking, high blood pressure, elevated blood glucose, and adiposity on national life expectancy and on disparities in life expectancy and disease-specific mortality among eight subgroups of the US population (the “Eight Americas”) defined on the basis of race and the location and socioeconomic characteristics of county of residence, in 2005.

Methods and Findings

We combined data from the National Health and Nutrition Examination Survey and the Behavioral Risk Factor Surveillance System to estimate unbiased risk factor levels for the Eight Americas. We used data from the National Center for Health Statistics to estimate age–sex–disease-specific number of deaths in 2005. We used systematic reviews and meta-analyses of epidemiologic studies to obtain risk factor effect sizes for disease-specific mortality. We used epidemiologic methods for multiple risk factors to estimate the effects of current exposure to these risk factors on death rates, and life table methods to estimate effects on life expectancy. Asians had the lowest mean body mass index, fasting plasma glucose, and smoking; whites had the lowest systolic blood pressure (SBP). SBP was highest in blacks, especially in the rural South—5–7 mmHg higher than whites. The other three risk factors were highest in Western Native Americans, Southern low-income rural blacks, and/or low-income whites in Appalachia and the Mississippi Valley. Nationally, these four risk factors reduced life expectancy at birth in 2005 by an estimated 4.9 y in men and 4.1 y in women. Life expectancy effects were smallest in Asians (M, 4.1 y; F, 3.6 y) and largest in Southern rural blacks (M, 6.7 y; F, 5.7 y). Standard deviation of life expectancies in the Eight Americas would decline by 0.50 y (18%) in men and 0.45 y (21%) in women if these risks had been reduced to optimal levels. Disparities in the probabilities of dying from cardiovascular diseases and diabetes at different ages would decline by 69%–80%; the corresponding reduction for probabilities of dying from cancers would be 29%–50%. Individually, smoking and high blood pressure had the largest effect on life expectancy disparities.

Conclusions

Disparities in smoking, blood pressure, blood glucose, and adiposity explain a significant proportion of disparities in mortality from cardiovascular diseases and cancers, and some of the life expectancy disparities in the US. Please see later in the article for the Editors'' Summary  相似文献   

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张亦弛  王珺哲 《生物信息学》2019,26(11):108-112
19世纪中叶,拿破仑三世启动了奥斯曼工程。这一闻名世界的改造计划不仅将巴黎打造为世界时尚之都,还促使其形成了独具一格的杂糅混合式城市公园风格,进而影响到整个欧洲的公园发展。但是,奥斯曼工程中公园建设的负责人和总设计师—阿尔方却较少受到关注。在英、法文原始资料的基础上,分析阿尔方在引入英国自然风景园、改良植物应用、创造杂糅混合式城市公园风格等方面所作的贡献,并将这些造园活动与法国第二帝国的社会文化背景相联系,指出阿尔方公园建设成功的关键在于其杂糅混合式城市公园所透露的公民权利及帝国荣耀完美契合了法兰西第二帝国所意图展现的意识形态。  相似文献   

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《PloS one》2013,8(12)

Background

Combination antiretroviral therapy (ART) has significantly increased survival among HIV-positive adults in the United States (U.S.) and Canada, but gains in life expectancy for this region have not been well characterized. We aim to estimate temporal changes in life expectancy among HIV-positive adults on ART from 2000–2007 in the U.S. and Canada.

Methods

Participants were from the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD), aged ≥20 years and on ART. Mortality rates were calculated using participants'' person-time from January 1, 2000 or ART initiation until death, loss to follow-up, or administrative censoring December 31, 2007. Life expectancy at age 20, defined as the average number of additional years that a person of a specific age will live, provided the current age-specific mortality rates remain constant, was estimated using abridged life tables.

Results

The crude mortality rate was 19.8/1,000 person-years, among 22,937 individuals contributing 82,022 person-years and 1,622 deaths. Life expectancy increased from 36.1 [standard error (SE) 0.5] to 51.4 [SE 0.5] years from 2000–2002 to 2006–2007. Men and women had comparable life expectancies in all periods except the last (2006–2007). Life expectancy was lower for individuals with a history of injection drug use, non-whites, and in patients with baseline CD4 counts <350 cells/mm3.

Conclusions

A 20-year-old HIV-positive adult on ART in the U.S. or Canada is expected to live into their early 70 s, a life expectancy approaching that of the general population. Differences by sex, race, HIV transmission risk group, and CD4 count remain.  相似文献   

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Life history theory predicts that greater extrinsic mortality will lead to earlier and higher fertility. To test this prediction, I examine the relationship between life expectancy at birth and several proxies for life history traits (ages at first sex and first marriage, total fertility rate, and ideal number of children), measured for both men and women. Data on sexual behaviors come from the Demographic and Health Surveys (DHS). Two separate samples are analyzed: a cross-sectional sample of 62 countries and a panel sample that includes multiple cross-sectional panels from 48 countries. Multivariate regression analysis is used to control for potential confounding variables. The results provide only partial support for the predictions, with greater support among women than men. However, the prediction is not supported in sub-Saharan African countries, most likely owing to the nonequilibrium conditions observed in sub-Saharan Africa with respect to life expectancy. The applicability of the model to understanding HIV/AIDS risk behaviors is discussed.  相似文献   

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This study examines secular trends in the magnitude of inbreeding in the Jewish community of Gibraltar over a 120 year period. Analysis of isonymous unions by socioeconomic status revealed distinctive differences between high versus mid/low status unions. Factors responsible for the elevated rate of inbreeding among the professional/mercantile class and its secular trend are discussed.  相似文献   

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Contemporary cognitive and neuropsychological approaches to dreaming show striking methodological and conceptual similarities with the scientific dream literature of the last century. The use of introspective dream reports and the emphasis on dream phenomenology are characteristic of both periods but were bannished during the first half of this century, the former by behaviorism, the latter by psychoanalysis. Three main common axioms of 19th century and contemporary dream research are described: (a) dream experience results from cognitive syntheses realized in the absence of external constraints; (b) dream narrative or dream coherency involves mental associative mechanisms; (c) dream bizarreness emerges from a cerebral state characterized by functional dissociation. According to these three axioms, the observation of dream phenomena reveals that distinct cognitive processes might function in a partly autonomous, automatic, and dissociated way, making dreaming a unique model of these cognitive processes.  相似文献   

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The paper deals with the transformation of plant breeding from an agricultural practice into an applied academic science in the late 19th and early 20th centuries Germany. The aim is to contribute to the ongoing debate about the relationship between science and technology. After a brief discussion of this debate the first part of the paper examines how pioneers of plant breeding developed their breeding methods and commercially successful varieties. The focus here is on the role of scientific concepts and theories in the agricultural innovation process. The second part turns towards the strategies by which agronomists tried to establish plant breeding as an academic discipline and themselves as the new experts for breeding research and varietal development. Again, the focus is on the interplay of scientific theory and agricultural practice. It is argued that in order to better understand the transformation of plant breeding into an applied academic science we have to take different levels into account, i.e. the levels of organizations, individuals and objects, at which science and technology interact.  相似文献   

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This article examines the relationship of obesity and arthritis to length of life and length of disabled life in older American men and women. Secondary data analysis is conducted on three waves of the Asset and Health Dynamics Among the Oldest Old (AHEAD) survey (n = 7,381). Using integrated Markov chains, total, active, and disabled life expectancy in Americans aged ≥70 is estimated, with and without obesity and arthritis. Results indicate that neither obesity nor arthritis is related to the length of life for older men and women, alone or in combination. However, both conditions are significantly individually associated with increased length of disabled life in older men (1.4 years attributable to obesity; 1.2 years to arthritis at age 70; P < 0.05) and women (1.7 years attributable to obesity; 2.1 years to arthritis at age 70; P < 0.05). In addition, the combination of the two is significantly related to decreased active life, with nearly 50 and 60% of remaining life for 70‐year‐old men and women lived with disability, respectively (P < 0.05). Coupled with the fact that both obesity and arthritis are growing in prevalence, these findings represent one of the few clearly negative health trends in older adults today. These results should provide incentives for health‐care professionals to make concerted efforts to address both conditions in clinical settings.  相似文献   

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A limited amount of research has been done on the body mass index values of 19th century Americans. This paper uses Texas prison records to demonstrate that, in contrast to today's distributions, most BMI values were in the normal range. Only 21.5% and 1.2% of the population was overweight or obese, while today comparable figures are 36% and 23%. There was also little change in BMI values between 1876 and 1919. Farmers were consistently heavier than non-farmers, while Southwestern men had lower BMI values than their counterparts from other regions of the US. BMI values indicate that 19th century African-Americans, and whites populations were well fed in spite of large expenditures on energy.  相似文献   

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Canavan disease: mutations among Jewish and non-jewish patients.   总被引:5,自引:4,他引:5  
Canavan disease is an autosomal recessive leukodystrophy caused by the deficiency of aspartoacylase (ASPA). Sixty-four probands were analyzed for mutations in the ASPA gene. Three point mutations--693C-->A, 854A-->C, and 914C-->A--were identified in the coding sequence. The 693C-->A and 914C-->A base changes, resulting in nonsense tyr231-->ter and missense ala305-->glu mutations, respectively, lead to complete loss of ASPA activity in in vitro expression studies. The 854A-->C transversion converted glu to ala in codon 285. The glu285-->ala mutant ASPA has 2.5% of the activity expressed by the wild-type enzyme. A fourth mutation, 433 --2(A-->G) transition, was identified at the splice-acceptor site in intron 2. The splice-site mutation would lead to skipping of exon 3, accompanied by a frameshift, and thus would produce aberrant ASPA. Of the 128 unrelated Canavan chromosomes analyzed, 88 were from probands of Ashkenazi Jewish descent. The glu285-->ala mutation was predominant (82.9%) in this population, followed by the tyr231-->ter (14.8%) and 433 --2(A-->G) (1.1%) mutations. The three mutations account for 98.8% of the Canavan chromosomes of Ashkenazi Jewish origin. The ala305-->glu mutation was found exclusively in non-Jewish probands of European descent and constituted 60% of the 40 mutant chromosomes. Predominant occurrence of certain mutations among Ashkenazi Jewish and non-Jewish patients with Canavan disease would suggest a founding-father effect in propagation of these mutant chromosomes.  相似文献   

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We report here trends in the usage of “mood” words, that is, words carrying emotional content, in 20th century English language books, using the data set provided by Google that includes word frequencies in roughly 4% of all books published up to the year 2008. We find evidence for distinct historical periods of positive and negative moods, underlain by a general decrease in the use of emotion-related words through time. Finally, we show that, in books, American English has become decidedly more “emotional” than British English in the last half-century, as a part of a more general increase of the stylistic divergence between the two variants of English language.  相似文献   

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Introduction

Since 2000, the world has been coalesced around efforts to reduce maternal mortality. However, few studies have estimated the significance of eliminating maternal deaths on female life expectancy. We estimated, based on census data, the potential gains in female life expectancy assuming complete elimination of pregnancy-related mortality in Zambia.

Methods

We used data on all-cause and pregnancy-related deaths of females aged 15–49 reported in the Zambia 2010 census, and evaluated, adjusted and smoothed them using existing and verified techniques. We used associated single decrement life tables, assuming complete elimination of pregnancy-related deaths to estimate the potential gains in female life expectancy at birth, at age 15, and over the ages 15–49. We compared these gains with the gains from eliminating deaths from accidents, injury, violence and suicide.

Results

Complete elimination of pregnancy-related deaths would extend life expectancy at birth among Zambian women by 1.35 years and life expectancy at age 15 by 1.65 years. In rural areas, this would be 1.69 years and 2.19 years, respectively, and in urban areas, 0.78 years and 0.85 years. An additional 0.72 years would be spent in the reproductive age group 15–49; 1.00 years in rural areas and 0.35 years in urban areas. Eliminating deaths from accidents, injury, suicide and violence among women aged 15–49 would cumulatively contribute 0.55 years to female life expectancy at birth.

Conclusion

Eliminating pregnancy-related mortality would extend female life expectancy in Zambia substantially, with more gains among adolescents and females in rural areas. The application of life table techniques to census data proved very valuable, although rigorous evaluation and adjustment of reported deaths and age was necessary to attain plausible estimates. The collection of detailed high quality cause-specific mortality data in future censuses is indispensable.  相似文献   

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