Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity

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Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5

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DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development

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EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity

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Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration

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Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs

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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

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Bone marrow hematopoiesis drives multiple sclerosis progression

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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin

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HIV-infected macrophages resist efficient NK cell-mediated killing while preserving inflammatory cytokine responses

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Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy

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Maturation of the neonatal oral mucosa involves unique epithelium-microbiota interactions

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STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth

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Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen

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DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells

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Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self

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Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function

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A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice

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TNFR2+ regulatory T cells protect against bacteremic pneumococcal pneumonia by suppressing IL-17A-producing γδ T cells in the lung

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Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation

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