T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection

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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion

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METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

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IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii

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AKT activity orchestrates marginal zone B cell development in mice and humans

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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment

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PD-1highCXCR5–CD4+ peripheral helper T cells promote CXCR3+ plasmablasts in human acute viral infection

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High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic γδ T cell IL-17 production

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The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function

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Bacteriophage antidefense genes that neutralize TIR and STING immune responses

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LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis

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CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection

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Oxoeicosanoid signaling mediates early antimicrobial defense in zebrafish

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Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions

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DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development

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The human placenta exhibits a unique transcriptomic void

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Organized B cell sites in cartilaginous fishes reveal the evolutionary foundation of germinal centers

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Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+ dendritic cell population

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Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants

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Vaccine adjuvant-elicited CD8+ T cell immunity is co-dependent on T-bet and FOXO1

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