Distribution and phasing of sequence motifs that facilitate CRISPR adaptation

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A replication fork determinant for the establishment of sister chromatid cohesion

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Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability

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Protein kinase ATR inhibits E3 ubiquitin ligase CRL4PRL1 to stabilize ribonucleotide reductase in response to replication stress

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Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps

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Structural characterization of dicyanopyridine containing DNMT1-selective,non-nucleoside inhibitors

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A FOXO-dependent replication checkpoint restricts proliferation of damaged cells

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HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway

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AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ

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SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation

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Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin

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Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations

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DNA Methylation and Histone H1 Jointly Repress Transposable Elements and Aberrant Intragenic Transcripts

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Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex

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MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends

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PARylation of BRCA1 limits DNA break resection through BRCA2 and EXO1

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The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer

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Mitochondrial NAD+ Controls Nuclear ARTD1-Induced ADP-Ribosylation

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MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells

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Structural insights into DarT toxin neutralization by cognate DarG antitoxin: ssDNA mimicry by DarG C-terminal domain keeps the DarT toxin inhibited

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