Topography of mutational signatures in human cancer

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Modulation of cellular metabolism by protein crotonylation regulates pancreatic cancer progression

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Cell-to-cell variability in Myc dynamics drives transcriptional heterogeneity in cancer cells

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MYO10 regulates genome stability and cancer inflammation through mediating mitosis

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Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells

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Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation

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Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer

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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression

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Premature aging and reduced cancer incidence associated with near-complete body-wide Myc inactivation

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Breast cancer cell mesenchymal transition and metastasis directed by DAP5/eIF3d-mediated selective mRNA translation

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Bacteriophage antidefense genes that neutralize TIR and STING immune responses

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LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis

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ALDH1L2 regulation of formate,formyl-methionine,and ROS controls cancer cell migration and metastasis

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Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING

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Oxoeicosanoid signaling mediates early antimicrobial defense in zebrafish

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Formate promotes invasion and metastasis in reliance on lipid metabolism

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The human placenta exhibits a unique transcriptomic void

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NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer

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Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

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Adhesion analysis via a tumor vasculature-like microfluidic device identifies CD8+ T cells with enhanced tumor homing to improve cell therapy

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