Lipid-mediated phase separation of AGO proteins on the ER controls nascent-peptide ubiquitination

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Super-resolution proximity labeling reveals anti-viral protein network and its structural changes against SARS-CoV-2 viral proteins

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TAOK2 is an ER-localized kinase that catalyzes the dynamic tethering of ER to microtubules

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Opto-katanin,an optogenetic tool for localized,microtubule disassembly

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A short isoform of STIM1 confers frequency-dependent synaptic enhancement

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ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance

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TMEM173 Drives Lethal Coagulation in Sepsis

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Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2

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Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking

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Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth

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VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites

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PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis

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Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection

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Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes

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A novel plant actin-microtubule bridging complex regulates cytoskeletal and ER structure at ER-PM contact sites

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TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation

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The ribosome collision sensor Hel2 functions as preventive quality control in the secretory pathway

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A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization

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Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites

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Coronavirus subverts ER-phagy by hijacking FAM134B and ATL3 into p62 condensates to facilitate viral replication

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