Verruca plantaris

Various methods were used in the treatment of 451 patients with verruca plantaris who were observed for a period of nine months after treatment. Results obtained by the various methods were as follows:[FORMULA: see text]     

A 2-year study of Candida-associated denture stomatitis treatment in aged care subjects

Objective: To test the efficacy of two methods of treatment for denture stomatitis in aged care institutions. Background data: Candida‐associated denture stomatitis has been associated with a lack of denture hygiene. Materials and methods: Sixty subjects with denture stomatitis were randomly divided into three groups: sodium hypochlorite denture soak, microwaving and control. Both methods of treatment were carried out on a nightly basis for 1 week, excepting the control group. Standardised photographs of the palate and microbial samples of palate, upper and lower dentures were taken before and after treatment. Results: Both hypochlorite and microwave irradiation significantly reduced the numbers of Candida and aerobic bacteria on both dentures and both methods significantly reduced Candida on the palate. However, palatal aerobic bacteria were not significantly reduced by either method and the controls showed insignificant changes at all three sites for both Candida and aerobes. Conclusion: While both methods of denture disinfection were successful, except for the counts of palatal aerobic bacteria, three independent observers of the clinical photographs had difficulty in identifying the controls but were more successful with the treatments. The raters also showed that there was no difference between both methods of disinfection and this agreed with the microbiological analysis.     

Physiotherapy for patients with soft tissue shoulder disorders: a systematic review of randomised clinical trials.

OBJECTIVE: To assess the effectiveness of physiotherapy for patients with soft tissue shoulder disorders. DESIGN: A systematic computerised literature search of Medline and Embase, supplemented with citation tracking, for relevant trials with random allocation published before 1996. SUBJECTS: Patients treated with physiotherapy for disorders of soft tissue of the shoulder. MAIN OUTCOME MEASURES: Success rates, mobility, pain, functional status. RESULTS: Six of the 20 assessed trials satisfied at least five of eight validity criteria. Assessment of methods was often hampered by insufficient information on various validity criteria, and trials were often flawed by lack of blinding, high proportions of withdrawals from treatment, and high proportions of missing values. Trial sizes were small: only six trials included intervention groups of more than 25 patients. Ultrasound therapy, evaluated in six trials, was not shown to be effective. Four other trials favoured physiotherapy (laser therapy or manipulation), but the validity of their methods was unsatisfactory. CONCLUSIONS: There is evidence that ultrasound therapy is ineffective in the treatment of soft tissue shoulder disorders. Due to small trial sizes and unsatisfactory methods, evidence for the effectiveness of other methods of physiotherapy is inconclusive. For all methods of treatment, trials were too heterogeneous with respect to included patients, index and reference treatments, and follow up to merit valid statistical pooling. Future studies should show whether physiotherapy is superior to treatment with drugs, steroid injections, or a wait and see policy.     

病理分期在颌颈部淋巴结核治疗中的价值

目的:探讨病理分期在颌颈部淋巴结核治疗中的价值,以期寻找颌颈部淋巴结核的最佳治疗方案。方法:收集我科近5年的临床资料,对颌颈部淋巴结核患者的发病及治疗情况作一临床统计,并结合淋巴结核的病理分期对之加以分析,寻找治疗规律。结果:所有颌颈部淋巴结核患者按病理分期采取不同治疗方案,均达到较佳治疗效果,处于病理初期和中期的患者,临床治疗周期明显小于常规化疗。结论:遵从病理分期治疗颌颈部淋巴结核是一种较为科学合理的治疗思路和方法。     

益生菌治疗结肠癌患者术后化疗相关性腹泻的效果观察

目的:探讨益生菌对结肠癌术后患者化疗相关性腹泻(CID)的治疗效果,为临床提供依据。方法:选择我院2011年1月-2013年6月结肠癌术后化疗并有CID患者85例,根据治疗方法分为对照组和观察组,其中对照组41例,按照常规治疗,观察组44例,在对照组基础上应用益生菌治疗;观察指标主要为患者平均腹泻持续时间、腹泻治疗效果以及不良反应。结果:观察组总有效率为93.18%(41/44),高于对照组78.05%(32/41)(P0.05);观察组腹泻持续时间为2.91±0.17d,低于对照组4.86±0.24d(P0.05);两组治疗后不良反应比较差异无统计学意义(P0.05)。结论:采用益生菌可以缩短CID持续时间,提高疗效,改善患者生活质量。     

阿托品压抑疗法和遮盖疗法治疗学龄儿童单眼弱视的临床效果

目的:探讨阿托品不同治疗方法对于学龄儿童单眼弱势的治疗效果。方法:回顾抽取我院眼科住院治疗的90例单眼弱视学龄儿童患者,根据疗法分成压抑组(压抑疗法)和遮盖组(短时遮盖疗法)各45例,对比分析两组患儿在视力、依从性、临床疗效和不良反应方面的差异性。结果:治疗后,压抑组患儿的视力、依从率(93.33%)、总有效率(91.11%)均显著高于遮盖组,且不良反应总发生率(15.00%)显著低于遮盖组(26.67%),差异具有统计学意义(P0.05)。结论:阿托品压抑疗法治疗学龄儿童单眼弱视具有疗效显著、依从性好、视力矫正效果明显、安全性好等优点,值得临床推荐。     

捏脊与按摩促进腹部术后胃瘫病人康复效果观察

目的：探讨促进腹部术后胃瘫病人康复的有效方法。方法：将152例术后胃瘫病人按入院的先后顺序分为观察组和对照组各76例。对照组采用一般疗法即肠内营养,饮依调理、血糖和电解质监测。观察组在一般治疗的基础上采用捏脊与按摩疗法。两周为一疗程,均治疗两个疗程后对两组治疗效果进行统计学处理（x2检验）。结果：观察组于治疗四周内胃肠功能全部恢复,整体疗效优于对照组（P〈0.01）具有非常显著性差异。结论：捏脊与按摩是促进腹部术后胃瘫病人康复的有效方法。     

Comparison of Methods of Extracting Intracellular Proteases from Bacteria

Five commonly used methods of disintegrating bacterial cells were compared by use of Bacillus subtilis, Pseudomonas putrefaciens, and Streptococcus durans as the test organisms. These methods were: (i) sonic treatment, (ii) grinding, (iii) freezing and thawing, (iv) acetone-powder, and (v) toluene. Sonic treatment and grinding yielded more protein in the cell-free extracts than did the other methods. Likewise, the protease activities (micrograms of tyrosine liberated per milliliter of extract) of sonically disrupted and ground cell extracts on casein substrates were far greater than those in extracts from cells disintegrated by the other methods. When the specific activity was based on the amount of tyrosine liberated per milligram of protein in the extract, the acetone-powder method yielded the most active protease extract, whereas the extract obtained by sonic treatment was least active. Other methods yielded extracts with intermediate specific activity.     

肾小球毛细血管内皮病合并甲状腺功能减低1例病例报道并文献复习

目的:通过分析我院收治的1例肾小球毛细血管内皮病合并甲状腺功能减退患者的诊治过程,结合相关文献,探讨此病的临床特点和诊疗方法。方法:报告北京军区总医院收治的1例肾小球毛细血管内皮病合并甲状腺功能减退病例的其临床资料及诊疗过程,并复习相关文献,对肾小球毛细血管内皮病合并甲状腺功能减退的病因、临床表现、诊断、治疗及预后进行分析,并总结其诊疗经验。结果:1例肾小球毛细血管内皮病合并甲状腺功能减退患者经综合治疗后病情好转出院,出院后继续接受对症治疗,目前患者恢复良好。结论:肾小球毛细血管内皮病的发病率低,合并甲状腺功能减退更少见,其发病原因不明,部分与药物、毒物或者病毒感染有关,多数病例对症治疗后预后较好。     

不同根管冲洗方法在瘘管型根尖周炎治疗中的疗效分析

目的:比较普通冲洗和超声冲洗方法对瘘管型慢性根尖周炎一次性根管治疗疗效的影响,以期为超声冲洗方法在慢性根尖周炎临床治疗中的应用提供指导。方法:将2010年6月-2012年6月来我科就诊的166名瘘管型慢性根尖周炎患者随机分为2组,超声冲洗组和普通冲洗组,根据分组分别在一次性根管治疗术中的根管清理过程采用超声根管冲洗方法和普通注射器冲洗方法,术后1周和半年时复诊记录患者一次性根管治疗效果,通过以患者术后1周内的主观"疼痛程度"作为短期评价指标和术后半年治疗效果作为长期评价指标进行比较,采用X2检验进行统计分析。结果:与普通注射器冲洗方法相比,超声冲洗方法可以明显减低一次性根管治疗后短期不适症状的发生率(P0.05),特别是重度反应的发生(P0.05);而术后出现的轻度和中度疼痛反应无明显差异。同时,超声冲洗方法可以明显增加一次性根管治疗术的长期成功率(P0.05)。结论:一次性根管治疗术中使用超声冲洗方法替代常规注射器冲洗方法,能够明显减轻患者短期术后以"疼痛"为主要表现的不适症状,提高一次性根管治疗术在瘘管型根尖周治疗中的长期成功率,是一种较为理想的根管治疗冲洗方法。     

老年膝关节骨性关节炎保守治疗与置换术的疗效对比分析

目的：比较老年膝关节骨性关节炎予以保守治疗以及外科膝关节置换手术的治疗效果,以探讨其合理的干预方法。方法：选 取我院2009 年1 月-2013 年12 月间收治的50 例临床资料完整的老年膝关节骨性关节炎疾病患者,将其根据治疗方式的不同分 为保守治疗组17 例以及外科手术治疗组33 例,手术方法为膝关节置换术。比较术后的KSS 评分情况,HSS评分、膝关节优良率。 结果：治疗后手术治疗组患者的KSS 评分较治疗前明显改善,P<0.05。治疗后外科手术组患者的HSS 各项评分均明显优于保守治 疗组,治疗后手术组患者的膝关节功能优良率达到了100 %（33/33）,明显优于保守治疗组35.29 %（6/17）的优良率,组间比较有统 计学差异,P<0.05。结论：对于老年膝关节骨性关节炎进行保守治疗可能不会对疾病的进展起到干预作用,而明确诊断的患者行全 膝关节置换术可以有效改善膝关节功能,提高生活质量。     

阿托伐他汀早期干预对2型糖尿病合并高血压患者血脂及炎症因子水平的影响

目的:探讨早期阿托伐他汀钙片干预对2型糖尿病合并高血压患者血脂水平和炎症指标的影响。方法:选择2014年5月-2015年5月我院收治的2型糖尿病合并高血压患者130例,根据治疗方法不同,将患者分为研究组和对照组,每组各65例。对照组采取常规降压及降糖药物治疗,研究组在此基础上应用阿托伐他汀钙片。观察两组患者治疗前后血脂水平、高敏C-反应蛋白(hs-CRP)、白介素-6(IL-6)及白介素-18(IL-18)的变化情况。结果:治疗后,两组患者胆固醇(TC)及低密度脂蛋白胆固醇(LDL-C)水平均较治疗前降低,且研究组显著低于对照组,差异具有统计学意义(P0.05);两组患者治疗前后的甘油三脂(TG)及高密度脂蛋白胆固醇(HDL-C)水平比较,差异无统计学意义(P0.05);治疗后,两组患者hs-CRP、IL-6及IL-18水平均较治疗前降低,且研究组显著低于对照组,差异具有统计学意义(P0.05);两组不良反应的发生率比较,差异无统计学意义(P0.05)。结论:阿托伐他汀钙片可以有效改善2型糖尿病合并高血压患者的血脂水症,降低血清炎症因子的表达,值得临床推广应用。     

Molecular monitoring of inactivation efficiencies of bacteria during pulsed electric field treatment of clinical wastewater

Aims: The applicability of an alternative wastewater disinfection concept based on the pulsed electric field (PEF) treatment is tested with molecular biology techniques using clinical wastewaters. Methods and Results: Hospital wastewater was treated with the PEF technology. The inactivation efficiencies of bacteria were successfully monitored with real‐time polymerase chain reaction (PCR). As the differentiation between living and dead bacterial cells is important for the determination of the disinfection efficiency, propidium monoazide (PMA) was applied. PMA selectively penetrates cells with compromised membranes and intercalates into the DNA inhibiting a subsequent PCR amplification. The rates of reduction were examined for specific pathogens and wastewater populations using PCR‐denaturing gradient gel electrophoresis. The results showed that the main part of the bacterial population could be inactivated efficiently with the PEF treatment. Moreover, it was demonstrated that naturally occurring nuclease activities were not affected by the PEF treatment in contrast to a thermal treatment. Conclusions: The results indicated that the PEF treatment is an appropriate alternative disinfection concept for the treatment of clinical wastewaters and surpass the disadvantages of other disinfection methods. Significance and Impact of the Study: With the use of propidium monoazide for live–dead distinction, a new concept could be developed for the evaluation of disinfection methods.     

超声乳化手术治疗慢性闭角型青光眼合并白内障的临床疗效分析

目的:探讨超声乳化手术治疗慢性闭角型青光眼合并白内障的临床效果。方法:慢性闭角型青光眼合并白内障64例(64眼)根据治疗方法的不同分为治疗组与对照组各32例,对照组采用传统小梁切除手术,治疗组采用超声乳化手术。结果:(1)两组术前视力对比无明显差异,治疗后视力情况都明显改善,同时组间对比有明显差异(P0.05)。(2)两组术前眼压比较无显著性差异,术后两组组间与组内对比都有明显差异(P0.05)。(3)两组术前前房深度比较无显著性差异,治疗后都有明显上升(P0.05),同时组间对比差异明显(P0.05)。(4)两组患者术中与术后都无严重并发症发生。结论:对于慢性闭角型青光眼合并白内障患者行超声乳化手术具备加深前房、控制眼压、提高视力的作用,同时安全性好,可作为标准治疗选择。     

Electromagnetic fields in medicine – The state of art

ABSTRACT

Introduction: Intense development of methods belonging to physical medicine has been noted recently. There are treatment methods, which in many cases lead to reduction treatment time and positively influence on quality of life treatment patients. Research implications: The present physical medicine systematically extends their therapeutic possibilities. This above applies to illnesses and injuries of locomotor system, diseases affecting of soft tissues, as well as chronic wounds. The aim of the study: The evidence on this are the results of basic and clinical examinations relating the practical use of electromagnetic fields in medicine. Originality: In this work the authors introduced the procedure using the current knowledge relating to physical characteristic and biological effects of the magnetic fields. In the work the following methods were used: static magnetic fields, spatial magnetic fields, the variable magnetic fields both with laser therapy (magnetolaserotherapy) and variable magnetic fields both with light optical non-laser (magnetoledtherapy) talked.     

不同治疗方式对产后压力性尿失禁的疗效评估

目的:探究不同方法治疗产后压力性尿失禁(stress urinary incontinence,SUI)的临床疗效,并分析其相关的产科影响因素,为该病的预防和治疗提供相关的依据。方法:选取2015年1月至2016年1月在汉川市人民医院于产后42天返院行盆底功能筛查时诊断为产后SUI同时符合纳入标准的初产妇103例,并将其按患者的意愿分为3个治疗组,随访观察组(I组)有30例患者,盆底肌锻炼组(II组)有35例患者,生物反馈联合电刺激治疗组(III组)有38例患者。分别治疗8周后,通过国际尿失禁咨询委员会尿失禁问卷表(ICI-Q-SF)问卷调查、尿垫试验及盆底肌力测定进行疗效评价,并分析生物反馈联合电刺激疗效的影响因素。结果:治疗前,三组间盆底肌力无显著性差异(P0.05);治疗后,三组间两两比较均有显著性差异(P0.05)。治愈率而言,III组与II组和I组比较,差异有统计学意义(P0.05)。单因素分析显示:孕期体重增加量与产后SUI严重程度和抑郁评分对生物反馈联合电刺激治疗疗效显著相关(P0.05),而年龄、产前BMI、新生儿出生体重等对治疗疗效无显著相关性(P0.05)。多因素非条件Logistic回归分析显示:孕期体重增加量与产后SUI严重程度是影响生物反馈联合电刺激治疗疗效的独立因素。结论:电刺激联合生物反馈治疗对产后SUI的疗效与单纯盆底肌锻炼治疗和单纯随访观察相比具有明显的优势,可作为临床治疗产后SUI的首选方案。影响其疗效的主要因素为孕期体重增加量与产后SUI严重程度,故控制孕期体重可能会促进电刺激对产后SUI的疗效。     

Clinical and microbiological efficacy of three different treatment methods in the management of denture stomatitis

Gerodontology 2010; doi: 10.1111/j.1741‐2358.2009.00354.x
Clinical and microbiological efficacy of three different treatment methods in the management of denture stomatitis Objective: This study evaluated. the effect of mouthrinses and tissue conditioner on the clinical findings and microbial flora of 60 patients with Newton’s type II denture stomatitis (N2DS) Background: Denture stomatitis is a common problem in complete denture wearers. Materials and methods: Sixty patients with N2DS were included in this study and divided into three groups. Two groups of patients were instructed to rinse their mouth with the designated mouthrinses DioxiDent and Corsodyl twice daily for 1 min and to soak their dentures overnight in these solutions for 15 days. For the third group, tissue conditioner was placed in each of 20 patients’ existing maxillary dentures. Patients were evaluated both clinically and microbiologically at baseline and after 15 days. Palatal swabs and smears were taken from each patient before and after treatment and these samples were examined mycologically. The difference between Candida colonisation before and after treatment and the differences between pre‐treatment and post‐treatment clinical findings were assessed. Results: DioxiDent and Corsodyl showed an improvement in palatal inflammation and a decrease in Candida colonisation compared to Visco‐gel. Conclusions: The effectiveness of topical chlorine dioxide and chlorhexidine gluconate in the management of N2DS was demonstrated.     

两种不同术式对老年股骨颈骨折治疗对比

目的:探讨全髋关节置换术与股骨头置换术治疗对比。方法:回顾性的分析对2007年1月-2008年12月年我院接收的70例60岁以上的老年股骨颈骨折的进行股骨头置换和全髋关节置换两组不同手术方式的临床资料。结果:两组股骨颈骨折治疗的手术时间、住院时间及术后并发症及治疗效果无明显统计学差异,两组术后半年到一年半的Harris评分较术前评分有显著的统计学意义。结论:人工股骨头置换术和髋关节置换是治疗老年股骨颈骨折的有效方法,可根据患者的自身情况、疾病特点等选择不同术式。     

Modification of bacterial structures by a low‐temperature gas plasma and influence on packaging material

Aims: To investigate the effect of a cascaded dielectric barrier discharge (CDBD) treatment on the biological structure of a selected bacterium and on the properties of different polymer films. Methods and Results: Inactivation kinetics were measured using air as the process gas and using Bacillus atrophaeus spores and vegetative cells, which had been homogeneously distributed on a surface. The changes to the outer coats and the DNA of the endospores and cells after plasma treatment were determined using biomolecular and chemical methods. The experiments showed that damage to the DNA molecules and changes in the cell walls can be observed as a consequence of the CDBD treatment. Furthermore, the influence of the plasma treatment on the properties of various polymer films was investigated using a variety of test methods. Except the sealing strength where a slight decrease was observed (max. 20%), no negative changes of the material properties have occurred. Conclusions: CDBD treatment can affect the DNA of spores and cells, depending on the treatment time. At the same time, practically relevant inactivation rates on packaging materials were observed, without any significant changes to the material properties. Significance and Impact of the Study: Knowledge about CDBD mechanisms was acquired from a biological point of view, and the suitability of the method for treating polymer films was demonstrated.     

中华眼镜蛇咬伤致局部组织损伤三种疗法的临床疗效观察

目的对中华眼镜蛇咬伤致局部组织损伤的各种治疗方法进行疗效优劣比较,找出最佳治疗方法。方法总结我院569例中华眼镜蛇咬伤致局部组织损伤的各种治疗方法。结果治疗方法从优到劣依次是：抗蛇毒血清局部注射-糜蛋白酶局部注射-蛇伤药酒外敷-坏死组织早期切除-局部烧灼法-局部组织切开冲洗。结论中华眼镜蛇伤致局部组织损伤的治疗方法应首选抗蛇毒血清局部注射和糜蛋白酶局部注射,其次选用蛇伤药酒外敷。